Saratov JOURNAL of Medical and Scientific Research

A rare case of Loeffler endocarditis associated with eosinophilic granuloma-tosis with polyangiitis

Year: 2017, volume 13 Issue: №4 Pages: 823-828
Heading: Internal Diseases Article type: Case report
Authors: Skryabina E.N., Safonova V.N., Agareva Т.А.
Organization: Saratov State Medical University

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare disease that affects small and medium-sized blood vessels of different organs, characterized by asthma, prominent peripheral blood eosinophilia. Cardiac involvement was reported in 20-50% and it is the major cause of mortality. A case of EGPA in a 43-year-old female, who had endocarditis, associated with thrombus formation in left ventricle, thromboembolic syndrome and recurrent stroke has been reported. The described case has showed that it is of crucial importance to perform the full cardiac imaging even in asymptomatic patients with suspected EGPA. The early identification of cardiac involvement may lead to better prognosis.

1. Systemic vasculitis. In: Russian clinical recommendations: Rheumatology. Moscow: GEOTAR-Media, 2017; p 180-204
2. Francis W, Kuwari MAAEA, Ghareep A-N, et al. A Rare right ventricular involvement of eosinophilic granulomatosis demonstrated by cardiac MRI. Pol J Radiol2016; 81: 598-601
3. Disease Churg — Strauss. In: Clinical rheumatology. 2nd ed. St. Petersburg: 000 "Izdatel Foliant", 2005; p. 325-327
4. Syndrome Churg — Strauss. In: Vasculitis and vasculopathy. Yaroslavl: Verkhnyaya Volga, 1999; p. 348-356
5. Syndrome Charge — Strauss. In: National guidelines for rheumatology. Moscow: GEOTAR-Media, 2008; p. 554-557 6. Beck KS, Jeong SY, Lee KY, et al. Native T1 mapping demonstrating apical thrombi in eosinophilic myocarditis associated with ChurgStrauss. Korean Circulation Journal 2016; 46 (6): 882-885
7. Semenkova EN. Systemic vasculitis. Moscow: Medicina, 1988; 112 p.
8. Jennette JC, Falk RJ, Bacon PA, et al. Revised International Chapel Hill Consensus Conference. Nomenclature of Vasculitides. Arthritis Rheum 2013; 65 (1): 1 -11
9. Qiao L, Gao D. A case report and literature review of Churg — Strauss syndrome presenting with myocarditis. Medicine (Baltimore) 2016; 95 (51): e5080.

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