Saratov JOURNAL of Medical and Scientific Research

diagnostics

Revisiting of etiology, clinical picture and diagnosis of the Kleine-Levin syndrome.

Year: 2017, volume 13 Issue: №1 Pages: 181-187
Heading: Neurology Article type: Case report
Authors: Ulyanova О.V., Kutashov V.A.
Organization: Voronezh State Medical Academy
Summary:

Objective: to draw the attention to the Kleine - Levin syndrome (SKL), a rare, poorly understood disease, not only in Russia but throughout the world. We analyzed the case of the 23-year old patient M, with the Kleine — Levin syndrome. SKL belongs to the group of recurrent hypersomnia and is characterized by long bouts of sleep lasting an average of 10-14 days, beginning with the imperative and difficulty awakening. During bouts of sleep observed unusual behavior of patients: hyperphagia; hypersexuality in males; irritability, restlessness, impaired mental activity; aggression; feeling of unreality of it all; confusion, hallucinatory episodes and depression in females. During wakefulness, marked dyspho-ria, emotional stupefaction, loss of memory. The syndrome develops in 4 times more often in men than in women, aged 12-25 years. Etiological factors: brain tumor, head trauma, metabolic disorders, acute infectious diseases with fever. Often the development of the syndrome is preceded by hyperemia and hypothalamic-pituitary dysfunction. The article discussed the etiology, diagnosis, and possible combinations of clinical manifestations in SKL.

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The modern view of the examination and treatment of patients with intracranial cystic formations

Year: 2017, volume 13 Issue: №1 Pages: 147-149
Heading: Neurology Article type: Author's opinion
Authors: Kolesov V.N., Lukina Е.М., Chekhonatsky А.А.
Organization: Saratov State Medical University
Summary:

Objective: to determine the diagnostic and treatment policy (conservative and operative) in patients with intracranial cysts of various origins. We observed 116 patients with different brain cystic formations. Diagnostic tactics and principles of treatment were refined. The evaluation of treatment results was made.

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Innovation in diagnostics and treatment of epilepsy

Year: 2017, volume 13 Issue: №1 Pages: 143-147
Heading: Neurology Article type: Review
Authors: Kalinin V.A., Poverennova I.E., Yakunina A.V., Beketova E.M.
Organization: Samara State Medical University, Municipal Hospital No. 1 n.a. N. I. Pirogov, Samara
Summary:

The aim of the review is try to systematize the innovative achievements of modern epileptology and indicate the levels of diagnosis and treatment of epilepsy that are not sufficiently developed, from our point of view. Applied to epileptology, the innovation process is realized at all levels. In principle, you can divide the entire process into a diagnostic and treatment level. Promising in the diagnosis of epilepsy should be considered the analysis of age characteristics, new methods of EEG analysis and evoked potentials, innovative methods of functional neuroimaging, genetic testing. New anticonvulsants with the original mechanism of action allow to overcome pharmaco-resistance of epilepsy in a number of observations. In rare cases it is necessary to use minimally invasive surgical methods of treatment.

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Modern methods of a localized scleroderma diagnostics

Year: 2016, volume 12 Issue: №3 Pages: 481-484
Heading: Dermatovenerology Article type: Review
Authors: Moiseyev А.А., Utz S.R.
Organization: Saratov State Medical University
Summary:

Localized scleroderma (LS) is a disease that is characterized by the appearance of inflammatory, sclerotic and/or atrophic changes in the affected areas of the skin and underlying tissues. In ICD-10, the disease is considered under category L94 "Other localized connective tissue changes". This paper presents the classification of the disease developed for federal guideline 2015, for management of patients with localized scleroderma. Also, a brief description of the various methods of diagnosis of the disease, including laboratory tests, instrumental methods and disease severity scale are presented.
Keywords: scleroderma, diagnostics, dermatology.

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Diagnosis and combined treatment of patients with locally advanced prostate cancer

Year: 2015, volume 11 Issue: №3 Pages: 317-322
Heading: Urology Article type: Review
Authors: Popkov V.M., Kim T.D., Ponukalin A.N.
Organization: Saratov State Medical University
Summary:

Prostate cancer is one of the most urgent problems of modern oncology. The article provides an overview of the methods of treatment of locally advanced prostate cancer, comparative characteristics, the advantages of both independent and combined methods. The results of multicenter studies have been stated.

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Modern strategy of diagnostics and treatment of NSAID-induced enteropathy in elderly

Year: 2015, volume 11 Issue: №1 Pages: 052-056
Heading: Gerontology and geriatrics Article type: Original article
Authors: Lipatova Т.Е., Dudaeva N.G.
Organization: Saratov State Medical University
Summary:

The aim of the research is to improve the efficiency of diagnosis and treatment of NSAID-induced enteropathy at elderly patients with chronic pain (osteoarthritis, dorsopathy). Material and Methods. 300 elderly with osteoarthritis or dorsopathies regularly (8 weeks or more) receiving diclofenac at 75 mg per day were inspected. Clinical features, morphology, components of the diffuse endocrine system of the small intestine were studied. Results. It is defined, that at elderly patients with regular use of NSAIDs in 25% of cases postbulbar erosive duodenitis, in 75% of cases inflammatory and atrophic changes of the distal duodenum were diagnosed. Diagnosis of NSAID-induced enteropathy at elderly should include faecal calprotectin and morphology analysis of postbulbar area of the duodenum. Use meloxicam and sulfasalazine at older patients helps to eliminate or reduce intestinal dyspepsia, malabsorption, and intestinal inflammation on the results of faecal calprotectin and of histology of the small intestine. Conclusion. Elderly patients are at high-risk group for NSAID-induced enteropathy due to functional disturbances in the neuroendocrine system of the small intestine.

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Modern methods of early diagnostics of juvenile arthritis

Year: 2013, volume 9 Issue: №2 Pages: 308-313
Heading: Pediatrics Article type: Review
Authors: Chernenkov Y.V., Zakharova N.B., Kuzmina А.А., Spivakovsky Y.M.
Organization: Saratov State Medical University
Summary:

The problem of inflammatory diseases of joints is one of the most important issues in the pediatrics. Nowadays the significant attention in this sphere is paid to the search of new accurate criteria of diagnostics. It will help estimate the severity of disease, determine the prognosis, choose the method of treatment and monitoring and evaluate the efficacy of the therapy.

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Colon polyps: epidemiology, risk factors, diagnostic criteria and courses of treatment

Year: 2013, volume 9 Issue: №2 Pages: 252-259
Heading: Internal Diseases Article type: Review
Authors: Lapteva Е.А., Kozlova I.V., Myalina J.N., Pakhomova A.N.
Organization: Saratov State Medical University
Summary:

Article focuses on the intestinal polyps. Intestinal polyps are considered to be obligatory precancerous diseases of the colon. Risk factors, epidemiology, clinical manifestations and diagnostic methods of polyps have been analyzed. The courses of treatment of colon polyps have been revealed.

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Case of calcifc panniculitis

Year: 2012, volume 8 Issue: №2 Pages: 603-607
Heading: Skin Diseases Article type:
Authors: Galkina E.M., Utz S.R., Slesarenko N.A., Yepifanova A.U., Roshchepkin V.V.
Organization: Saratov State Medical University
Summary:

The study presents clinical observations of a patient with calcifying panniculitis as well as the analysis of factors that contribute to the development of this pathology. Comprehensive medical examination of the patient has been performed in order to identify the accompanying pathologies.

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THE POSSIBILITIES OF VERIFICATION OF SYPHILITIC AFFECTION OF THE NERVOUS SYSTEM

Year: 2012, volume 8 Issue: №2 Pages: 469-475
Heading: Neurology Article type: Review
Authors: Kolokolov O.V., Bakulev A.L., Kolokolova A.M., Abramova T.P.
Organization: Saratov State Medical University
Summary:

We present modern laboratory methods of syphilis and neurosyphilis diagnostics. The question of verifcation of neurosyphilis form by using methods of neuroimaging and neurophysiology is discussed.

Keywords: diagnostics
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