Saratov JOURNAL of Medical and Scientific Research

Case report

Rituximab treatment efficacy in a patient with systemic lupus erythematosus with severe thrombocytopenia

Year: 2018, volume 14 Issue: №3 Pages: 417-419
Heading: rheumatology Article type: Case report
Authors: Alexandrova O.L., Nikitina N.M., Magdeeva N.A., Shmelkova M.Yu., Grigoryeva S.N.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University
Summary:

The article presents a clinical case of systemic lupus erythematosus with severe thrombocytopenia in a 55 year old patient. The standard therapy of usage of high doses of glucocorticoids, cyclophosphamide and intravenous im-munoglobulin was not effective. Application of Rituximab improved the course of disease, decreased the severity of thrombocytopenia, led to disappearance of leucopenia and anemia.

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Techniques of augmentation and full-endoscopic decompression in the treatment of patients with vertebral fractures of osteoporotic origin

Year: 2018, volume 14 Issue: №3 Pages: 412-416
Heading: neurosurgery Article type: Case report
Authors: Kravtsov M.N., Mirzametov S.D., Svistov D.V.
Organization: Military Medical Academy n.a. S. M. Kirov
Summary:

The article highlights debatable questions concerning the effectiveness of surgical treatment of osteoporotic vertebral fractures. The reasons of unsuccessful outcomes of vertebroplasty are analyzed. A combined method of surgical treatment is proposed, including vertebroplasty and full-endoscopic foraminotomy with a combination of local and ra-dicular pain syndrome caused by stenosis of the intervertebral foramen. A clinical example is given.

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A clinical case of fungal dacryocanaliculitis

Year: 2018, volume 14 Issue: №2 Pages: 217-219
Heading: Ophtalmology Article type: Case report
Authors: Krasyuk E.Yu., Strelnikova N.V.
Organization: Tambov Ophthalmological Clinical Hospital
Summary:

Objective: to study the clinical case of a patient with fungal dacryocanaliculitis. The patient with dacryocanaliculitis received a standard ophthalmological examination and tests with the disappearance of the dye. The contents of the lacrimal duct were examined. Only a comprehensive examination of the patient using various diagnostic methods may allow specialists to make a diagnosis and to administer the necessary treatment.

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Clinical case of favourable outcome at a patient with eosinophilic granulomatosis with polyangiitis complicated by severe heart disease

Year: 2018, volume 14 Issue: №2 Pages: 207-209
Heading: Internal Diseases Article type: Case report
Authors: Alexandrova O.L., Skryabina E.N., Nikitina N.M., Romanova I.A., Alexandrova N.L.
Organization: Saratov State Medical University
Summary:

The aim of the article is to present a clinical case of rapid generalization of eosinophilic granulomatosis with polyangiitis. The course of disease with multiple organ lesions and the heart being affected the most is described. Remission is achieved by combined therapy with corticosteroids and cyclophosphamide.

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On the clinical picture and diagnosis of rare neurological diseases

Year: 2018, volume 14 Issue: №1 Pages: 174-177
Heading: Neurology Article type: Case report
Authors: Ulyanova O.V., Kutashov V.A., Brezhneva N.V.
Organization: Regional Children's Clinical Hospital No. 1 (Voronezh), Voronezh State Medical Academy
Summary:

 The article presents clinical observation of patient H, 2007 year of birth., with X-linked adrenoleukodystrophy (X-ALD). This is a rare hereditary metabolic disease, not only in Russia but also worldwide. It belongs to the group of peroxisomal diseases, is associated with the accumulation of fatty acids with a very long chain and is characterized by a combined lesion of the nervous system and adrenal glands. X-ALD in neurology and Pediatrics require a targeted individual approach to each patient, genetic tests in relatives and prenatal diagnosis among patients at risk.

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Neuroinfection in patient with HIV: case report

Year: 2018, volume 14 Issue: №1 Pages: 168-173
Heading: Neurology Article type: Case report
Authors: Sotskova V.A., Bachilo Е.М., Shuldyakov А.А., Kolokolov O.V., Barylnik Yu.B., Potemina L.P., Krajnova O.N.
Organization: Saratov Regional Centre for Disease Prevention and Control of AIDS
Summary:

Toxoplasmosis is one of the most common opportunistic infections in HIV-positive patients. The onset of HIV-infection with cerebral toxoplasmosis makes this disease a multidisciplinary problem and requires the participation of doctors of various specialties (infectious disease specialists, neurologists, neurosurgeons, general practitioners, etc.). Early diagnosis and treatment of this disease will reduce the risk of deaths and severe consequences. We carry out an analysis of the clinical case of toxoplasma encephalitis in a HIV-infected patient. We have identified errors in the establishing diagnosis. We have given a detailed account a patient management plan. We also comment on some of the problem early disease detection HIV-infection.

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Ohtahara II sydrome as a rare epileptic encephalopathy

Year: 2018, volume 14 Issue: №1 Pages: 123-126
Heading: Neurology Article type: Case report
Authors: Akhmadeeva L.R., Vashkevich A.G., Vorontsova L.M.
Organization: Bashkir State Medical University of the Russian Health Care, Ufa "Lege Artis" Clinic
Summary:

We present information about Ohtahara II syndrome which is a rare epileptic encephalopathy, and our own clinical
case: a 4-year old child with this disorder.

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A case report of appendicular abscess resulted in hernial sac phlegmon

Year: 2018, volume 14 Issue: №1 Pages: 94-96
Heading: Surgery Article type: Case report
Authors: Shapkin Yu.G., Katalnikov A.E., Starchikhina D.V.
Organization: Saratov City Hospital No6 n.a. V. N. Koshelev, Saratov State Medical University
Summary:

An abnormal clinical case of break of appendicular abscess in incisional ventral hernia complicated phlegmon of
anterior abdominal wall is reported. The observation is of significant importance due to rare frequency of occurrence
in clinical practice, formation of a dangerous complication (phlegmon of anterior abdominal wall), difficult differential
diagnostics (Richter’s strangulatoin bowel or epiploon in hernia with necrosis complicated hernial sac phlegmon or
break of appendicular abscess in incisional ventral hernia). The surgical management was performed followed by a
patient’s recovery.

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A rare cause of small bowel obstruction (case report)

Year: 2017, volume 13 Issue: №4 Pages: 846-848
Heading: Surgery Article type: Case report
Authors: Khmara M.B., Kozlov V.V., Samarina D.V.
Organization: Saratov State Medical University
Summary:

The article presents a rare case of obstructive ileus caused by a silicone cylinder that is installed within a stomach to treat obesity. Purpose: to show the possibility of developing intestinal obstruction by foreign body (silicone balloon) and to draw the attention of professionals involved in intragastric ballooning to the possibility of the development of this complication.

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Pulmonary lymphangioleiomyomatosis (case report)

Year: 2017, volume 13 Issue: №4 Pages: 828-833
Heading: Internal Diseases Article type: Case report
Authors: Shashina M.M., Shapovalova T.G., Kazimirova N.E., Ryabova A.Y., Arkhangelskaya Е.Е., Lifanova D.V., Chernyshkova M.A.
Organization: Saratov State Medical University, Saratov Clinical Hospital № 8
Summary:

This article presents a clinical observation of a patient with a proven diffuse-nodular form of lymphangioleiomyomatosis of the lungs. Features of the course of the process against the background of pathogenetic therapy which included sirolimus and progesterone have been considered. It is necessary to raise awareness of doctors about the disease that facilitates timely diagnosis and treatment.

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