Saratov JOURNAL of Medical and Scientific Research

Case report

Surgical treatment of the patient with keratectasia after keratotomy followed by LASIK

Year: 2019, volume 15 Issue: №2 Pages: 544-546
Heading: Ophtalmology Article type: Case report
Authors: Syrykh I.Yu., Gavilovskaya V.A., Fabrikantov O.L.
Organization: S. Fedorov Eye Microsurgery Federal State Institution
Summary:

A clinical case of treating a patient with keratoectasia after keratotomy followed by LASIK is presented

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Mechanisms of optic nerve damage in patients with hemoblastosis

Year: 2019, volume 15 Issue: №2 Pages: 482-485
Heading: Ophtalmology Article type: Case report
Authors: Ioyleva E.E., Gadzhieva N.S., Zinovyeva A.V.
Organization: "Eye Microsurgery" n.a. academician S. N. Fedorov, Volgograd branch, Moscow State Medical Stomatological University n.a. A. I. Evdokimov
Summary:

The development of optic neuropathy in leukemia and lymphomas has a wide range of etiological factors, being a result of neoplastic, infectious, compression, ischemic and toxic damage. Patients in the older age group may have cardiovascular risk factors that increase the risk of developing lesions of the optic nerve. Timely diagnosis of optic neuropathy in hemoblastosis and the choice of the optimal treatment method allow to maintain high visual function and improve patients» quality of life. The paper presents a clinical case of unilateral ischemic neuropathy in patients with clinical and hematological remission of acute myeloblastic leukemia and the presence of cardiovascular risk factors, as well as heart failure.

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Results of a seven-year follow-up of an atypical form of multiple sclerosis, Marburg variant

Year: 2019, volume 15 Issue: №2 Pages: 414-418
Heading: Ophtalmology Article type: Case report
Authors: Andrusyakova Ye.P., Ioyleva Ye.E., Safonenko A.Yu., Krivosheeva M.S., Pis'menskaya V.A.
Organization: "Eye Microsurgery" n.a. academician S. N. Fedorov, Volgograd branch, Moscow State Medical Stomatological University n.a. A. I. Evdokimov
Summary:

Marburg disease afects young people and is characterized by an acute onset with a fulminant course. The disease leads to death within 1 year from the onset of symptoms. In Academician S. N. Fedorov «Eye Microsurgery» Center (Moscow) a patient with Marburg multiple sclerosis was followed up for seven years. Standard treatment in combination with physiotherapy treatment slowed the development of an irreversible decrease in visual function due to atrophy of the optic nerves.

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Twin-to-twin transfusion syndrome: A clinical case

Year: 2019, volume 15 Issue: №2 Pages: 236-240
Heading: Pediatrics Article type: Case report
Authors: Nechaev V.N., Chernenkov Yu.V.
Organization: Saratov State Medical University
Summary:

At the heart of the development of twin-to-twin transfusion syndrome (TTTS) is the presence of pathological anastomoses in the placental vascular network. The article presents a clinical case of TTTS development in monochorionic twins with placental vessel abnormality with a diagnostic search and a plan of further management.

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Balloon pulmonary angioplasty — an efective method of treatment for patients with pulmonary arterial hypertension

Year: 2019, volume 15 Issue: №2 Pages: 222-224
Heading: Cardiology Article type: Case report
Authors: Starodubtseva I.A.
Organization: Voronezh State Medical University n.a. N.N. Burdenko
Summary:

The article presents the clinical case of patient with chronic thromboembolic pulmonary hypertension. It is describes the classical course of the disease with use of full spectrum of diagnostic procedures. Pulmonary endarterectomy (PEA) is a gold standard of treatment. Nevertheless, performance of PEA is possible in only 60 % of patients with chronic thromboembolic pulmonary hypertension. Balloon pulmonary angioplasty and drug therapy with a stimulator of soluble guanylate cyclase are alternative treatment strategy.

Clinical case of the manifestation of Parkinson's disease in a patient with neuro-leptic-induced parkinsonism

Year: 2019, volume 15 Issue: №1 Pages: 199-202
Heading: Neurology Article type: Case report
Authors: Yudina V.V., Makarov N.S., Yudina G.K.
Organization: Saratov State Medical University
Summary:

The article presents data on the mechanisms of development of drug-induced parkinsonism in patients taking neu-roleptic drugs, as well as on specifics of the development of Parkinson's disease in these patients. A clinical case of Parkinson's disease development in a patient with drug-induced parkinsonism who has been taken antipsychotics for a long time is described.

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Idiopathic syringomyelia with involvement of all segments of spinal cord

Year: 2019, volume 15 Issue: №1 Pages: 180-182
Heading: Neurology Article type: Case report
Authors: Sergeeva А.А., Serebrennikov N.A.
Organization: First City Clinical Hospital n.a. E.E. Volosevich of Arkhangelsk, Northern State Medical University
Summary:

Syringomyelia is a chronic disease with multiple etiologies characterized by a progressive development of longitudinal cavities within spinal cord, which are filled with cerebrospinal fluid or a liquid of similar composition. Etiologically syringomyelia is most often associated with type 2 Chiari malformation. One of the least common variants is an idiopathic syringomyelia. The article describes a rare clinical case of idiopathic syringomyelia with involvement of all spinal cord segments and the outcomes of its surgical treatment using syringo-subarachnoid shunting techinque.

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Characteristics of clinical findings and diagnostics of acute cerebral venous circulation disorder in immediate period following neurosurgical intervention for peripheral lung cancer metastasis into brain

Year: 2019, volume 15 Issue: №1 Pages: 67-71
Heading: Traumatology and Orthopedics Article type: Case report
Authors: Bazhanov S.P., Ulyanov V.Yu., Matveeva O.V., Tolkachev V.S., Shuvalov S.D.
Organization: Saratov State Medical University
Summary:

A rare case of cerebral venous circulation disorder in a female patient with peripheral cancer metastasis of the right lung upper lobe to the area of precentral and postcentral gyri of the left cerebrum hemisphere in the immediate post- surgical period is present. It has been shown that the diagnostics of impaired circulation throuth the superficial cerebral veins is rather complicated due to the lack of clinical symptoms specificity and poor sensitivity of neurovisualization methods.

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Congenital megakaryoblastic leukemia: A clinical case

Year: 2019, volume 15 Issue: №1 Pages: 34-40
Heading: Pediatrics Article type: Case report
Authors: Nechaev V.N., Chernenkov Yu.V., Mishina O.A., Fedorova Yu.A., Averyanov A.P.
Organization: Clinical Perinatal Center of the Saratov Region, Saratov State Medical University
Summary:

Leukemia in children (leukemia) is a systemic hemoblastosis, accompanied by a violation of bone marrow hemato- poiesis and replacement of normal blood cells with immature blast cells of the leukocyte series. Acute megakaryoblastic leukemia-one of the rarest forms of acute leukemia (1-3% of all leukaemias), which is characterized by the presence in the blood and bone marrow, along with undifferentiated blasts also megakaryoblasts, ugly megakaryocytes and platelet clusters. The work presents a clinical case of congenital acute megakaryoblastic leukemia in the child S., combined with the mosaic form of Down syndrome and a congenital heart defect.

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Rod-cone dystrophy with mutation in GUCY2D gene (clinical case)

Year: 2018, volume 14 Issue: №4 Pages: 928-931
Heading: Ophtalmology Article type: Case report
Authors: Zolnikova I.V., Kadyshev V.V., Zinchenko R.A., Egorova I.V.
Organization: Moscow Helmholtz Research Institute of Eye Diseases, Research Centre for Medical Genetics
Summary:

The cinical case of rod-cone dystrophy (retinitis pigmentosa sine pigmento) in a patient with mutation in GUCY2D gene is described Mutations in GUCY2D gene are the common cause of Leber Congenital Amaurosis (LCA1, OMIM 204000), central areolarchoroidal dystrophy (CACD1 OMIM 215500), mutations in heterozygous, compound heterozygous and homozygous state are described in cone dystrophy CORD6 (OMIM 601777), but have not been described in rod-cone dystrophy. In patient who complained of nictalopia decrease of the best corrected visual acuity to 0.7 OD and 0.9 OS was revealed. Maximal electroretinogram was subnormal, which indicated decrease in the function of peripheral retina. 30 Hz flicker and macular ERG were within normal range. Not described previously as pathogenic variant of nucleotide sequence in exon 11 of GUCY2D gene (chrl 7:7916486G>A), causing missense mutation (p. Gly727Ser, NM_000180.3) in heterozygous state in patient was revealed. Thus we are first to describe genotype-phenotype associations of rod-cone degeneration with mentioned above pathological in GUCY2D gene.

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