Saratov JOURNAL of Medical and Scientific Research

Efficiency analysis of laser magnetic stimulation of an eye drainage system in the treatment of patients with different stages of primary open angle glaucoma based on developments of functional indicators and biochemistry factors

Year: 2017, volume 13 Issue: №2 Pages: 406-411
Heading: Ophtalmology Article type: Original article
Authors: Filatova V.S., Kamenskikh T.G., Zaharova N.B.
Organization: Saratov State Medical University

The purpose of study is to develop efficiency analysis of laser magnetic stimulation of an eye drainage system in the treatment of patients with primary open angle glaucoma (POAG). Material and Methods. The study included 197 patients with established diagnosis of POAG. The first group included 104 patients treated with drug treatment and laser magnetic stimulation of the drainage system of the eye using the «AMO-ATOS-ICL». The second group included 93 patients who received only drug therapy. Patient underwent visometry, oftalmobiomicroscopy, threshold perimetry electrophysiological study, the study of intraocular blood flow, level of VEGF and MCP-1. Results. A comparative analysis showed that the use of laser magnetic stimulation eye's drainage system in the treatment of patients with different stages of POAG to an activation of intraocular blood flow, but it was more significant in patients of the main group who were diagnosed with I and II stages of POAG. The decrease in intraocular blood flow resulted in ischemia while the level of VEGF increased. Conclusion. Analysis of clinical, electrophysiological and hemodynamic parameters in treatment of patients with POAG before and after laser magnetic stimulation improved of the state of the visual system in comparison with those in control group.

Keywords: MCP-1, VEGF

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