Saratov JOURNAL of Medical and Scientific Research

2010, volume 6

Diagnostics of evolution of risk collapse complications at student group with anomalous cardiovascular reaction

Year: 2010, volume 6 Issue: №3 Pages: 615-619
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Usanov D.A., Protopopov А.А., Skripal A.M, Averyanov A.P., Repin V.F., Rytik A.P., Vagarin A.Yu., Kuznetsov M.A., Petrova M.G.
Organization: Saratov National Research University n.a. N. G. Chernyshevsky, Saratov State Medical University
Summary:

The description of investigation of predisposition to potential danger of collapse complications at 429 first-year students during physical training is presented using the analysis of pulse wave form. With the help of developed device the group of students with predisposition to risk of collapse complications during physical activity has been revealed. The results of clinical examination have confirmed the predisposition of the given group to risk of collapse complications

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X-rays referral in an emergency department

Year: 2010, volume 6 Issue: №3 Pages: 612-614
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Gazzaz Zohair Jamil, Dhafar Khalid Obeid, Sindy Abdul Fatah, Farooq Mian Usman, Mian Shakeel Ahmad
Organization: Al-Noor Specialist Hospital, Makkah, Saudi Arabia
Summary:

This study highlighted referral rate for X-rays with positive findings in an Emergency department of a tertiary care hospital in Makkah, Saudi Arabia. This was a retrospective review of Emergency department(ED) cards/files of patients visited (ED) of Alnoor Specialist Hospital, Makkah, Saudi Arabia, during the month of April, 2006G. The total of 660 (22%) out of 2980 ED patients were included in the study and 1472 X-rays of different regions were done for them. Majority 288 (43.3%) were below 24yrs of age while males 372 (56.3%) and Saudis 400 (60%) were predominant. The discharged patients were 572 (86.6%), and 4(0.6%) were died. Six hundred and twenty (93.9%) patients got exposures rang of 1-4 while only four (0.6%) got more than eight exposures to X-rays. It was found that lower limb was exposed 384 times (26%), followed by chest 320 (21.7%). Overall 240 (16.3%) X-rays had positive findings with majority of upper limb 60 (50%) followed by chest 72 (22.5%). Pelvis & perineum had no positive X-ray. Patients from injury & poisoning were predominant 224 (33.9%) followed by respiratory disorders 104 (15.7%). Eighty four percent X-rays had no positive findings. Majority of X-rays were done for lower limb. Neck, pelvis & perineum X-rays had no positive findings

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On the optimization of clinicosonographic and biochemical diagnostics of gall-bladder disease

Year: 2010, volume 6 Issue: №3 Pages: 607-611
Heading: Internal Diseases Article type: Original article
Authors: N.V. Yekimova, Yu.l. Skvortsov, V.B. Lifshits, V.G. Subbotina, N.Yu. Papshitskaya, M.L. Tiunova, L.M. Chibrikova, I.D. Pavlischeva, D.S. Timofeev
Organization: Saratov State Medical University, Saratov City Hospital №9, Engels City Hospital of Emergency
Summary:

Determination of serum lipidic spectrum (increase of total cholesterol, atherogenic rate) for dynamic control of possible transformation in cholelithiasis is necessary to be included in examination of patients with cholecystitis. Changes in serum lipidic level (increase of total cholesterol, rate of total cholesterol to cholesterol of lipoproteins of high density and decrease of lipoproteins of high density) in healthy people promote forming risk group of gall-bladder cholestherosis

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Pharmacoeconomic efficacy of complex medical and climatic treatment of atopic asthma in Teberda resort

Year: 2010, volume 6 Issue: №3 Pages: 605-607
Heading: Internal Diseases Article type: Original article
Authors: Erkenova Z.T.
Organization: Karachai-Circassian State Technological Academy, Medical Institute
Summary:

120 patients with atopic asthma have been divided into two groups: the control group (60 patients) - has been treated with budesonide and formoterol combination (Cymbicort Turbuhaler) in individual doses; the main group (60 patients) additionally has being taken a course of climatic therapy in Teberda resort for 21 days. Common pharmacoeconomic analysis has been carried out with study of «expenses-efficiency» balance. Statistic results have been processed with Statistica 6,0 program. Complex of medical and climatic treatment of atopic asthma in Teberda resort promoted twice reduction of Cymbicort Turbuhaler dosage in 63,33% of patients while holding asthma control. Main group patients significantly rarely asked for stationary, out-patient or emergency aid; so it helped to reduce yearly expenses for 1 patient treatment to 51, 69%. Complex medical and climatic treatment of atopic asthma in Teberda resort allows to reduce pharmacoeconomic expenses significantly and to improve disease course

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Heart rate variability, structural and functional characteristics of the left ventricle in essential arterial hypertension

Year: 2010, volume 6 Issue: №3 Pages: 600-605
Heading: Internal Diseases Article type: Original article
Authors: Khromtsova О.М.
Organization: Uralsk State Medical Academy
Summary:

For the purpose of diagnostic and treatment improvement it is necessary to investigate relationship between different pathogenetic mechanisms in essential hypertension. The aim of our study was the comparative analysis of the parameters of cardiac remodeling and neurohumoral mechanisms of heart rate variability (HRV) in patients with essential arterial hypertension. 100 patients with essential arterial hypertension were included in the study. All patients went through heart rate variability parameters and left ventricle characteristics evaluation. Time and frequency domains were decreased in patients with arterial hypertension. Excess sympathetic activation takes place, parasympathetic system is depressed and it shows pathogenetic basis of disadaptation. Left ventricle hypertrophy is associated with progressive decrease of HRV and its circadian fluctuations. Concentric left ventricle hypertrophy is characterized by the most significant decrease in time and frequency domains of HRV. 1/3 of hypertensive patients with normal left ventricle geometry have diastolic dysfunction and also some decrease in time and frequency domains. In conclusion, we found that cardiac remodeling in patients with essential hypertension seems to be related to the severity of impairment of cardiac autonomic control

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Anemic syndrome in hospitalized patients with ischemic heart disease: inflammation marker or factor of pathogenesis?

Year: 2010, volume 6 Issue: №3 Pages: 596-600
Heading: Internal Diseases Article type: Original article
Authors: Suvorova S.A., Parkhonyuk Е.М., Shvarts Yu.G.
Organization: Ulyanovsk Central City Clinical Hospital, Saratov State Medical University
Summary:

The article presents the research results on the correlation between anemic syndrome and main risk factors in hospitalized patients with different forms of cardiovascular pathologies. This category of patients is characterized by more severe arterial hypertension and low level of total cholesterol in blood. It has been revealed that anemia in patients with CVD (cardiovascular diseases) is not only associated with unfavorable prognosis, but also becomes a marker of peculiarities in mechanism of disease development indicating the severity of inflammatory component

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Peculiarities of dyslipidemia in patients with psoriatic arthritis: connection with atherosclerosis, cardiovascular risk factors and inflammation activity

Year: 2010, volume 6 Issue: №3 Pages: 592-596
Heading: Internal Diseases Article type: Original article
Authors: Rebrov A.P., Gaydukova I.Z.
Organization: Saratov State Medical University, Saratov Regional Clinical Hospital
Summary:

Objective: to found the dyslipidemia in patients with psoriatic arthritis and to study the connection between dyslipidemia and cardiovascular risk factors, atherosclerosis and inflammation activity. 40 persons with PsA without cardiovascular diseases were involved in the study, 25 healthy people were examined like controls. Activity of PsA was learned by DAS, Likert index, Ritchie Arthicular Index, Number of swelling joints (NSJ), ESR, C-reactive protein (CRP) and fibrinogen. Total cholesterol, triglycerides, low and high density lipoprotein cholesterol, hypertension, body mass index, individual cardiac history were performed like cardiovascular risk markers. The ultrasound measuring the thickness of intima-media layer (IML) in carotid arteries was performed to subclinical atherosclerosis study. Increase of total cholesterol, triglycerides and low density lipoprotein cholesterol level was found in patients with PsA comparative with controls. There was prevalence of high and moderate increase of total cholesterol in patients with PsA, and in controls only low increase was measured. Correlation between total cholesterol and NSJ, fibrinogen, hypertension and IML was found. Low density lipoproteins were tingly interrelated with ESR, hypertension and IML. Very low density lipoproteins were connected with age of disease beginning, hypertension and IML, and triglycerides-with hypertension, enthesitis and dactilitis. Dyslipidemia in patients with PsA characterizes by total cholesterol, triglycerides, low density lipoprotein cholesterol increase, but not high density lipoprotein decrease. There is the connection between dyslipidemia in PsA and inflammation activity, arterial hypertension and IML

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CAT-test significance in life quality assessment in patients with chronic obstructive pulmonary disease

Year: 2010, volume 6 Issue: №3 Pages: 588-592
Heading: Internal Diseases Article type: Original article
Authors: Protasov A.D., Zhestkov A.M, Shanina I.Yu.
Organization: Samara State Medical University
Summary:

Comprehensive analysis of the impact of complex vaccination against pneumococcus, Haemophilus influenzae type b and influenza on performance CAT-test 6 months after vaccination in patients with chronic obstructive pulmonary disease compared with unvaccinated patients. 1 group - 48 patients with chronic obstructive pulmonary disease, vaccinated simultaneously «Pneumo-23», «Hiberix», «Grippol plus» (mean age - 61,46±1,17 years). Group 2-80 non-vaccinated patients with chronic obstructive pulmonary disease (mean age - 54,65±0,6 years). Patients from both groups held CAT-test at baseline and 6 months after. There was a significant decline in CAT-test after 6 months in the vaccinated patients compared with unvaccinated patients with chronic obstructive pulmonary disease.
CAT-test can be used as a sensitive tool to monitor indicators of quality of life in patients with chronic obstructive pulmonary disease in the process of therapy. Complete vaccination against pneumococcus, Haemophilus influenzae type b infection and influenza contributes to improving the quality of life in patients with chronic obstructive pulmonary disease in 6 months after medical intervention

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Objective evaluation of life quality of patients with ischemic heart disease

Year: 2010, volume 6 Issue: №3 Pages: 585-588
Heading: Internal Diseases Article type: Original article
Authors: D.A. Osipov, T.V. Rozhdestvenskaya, I.L. Krom, А.Р. Rebrov
Organization: Saratov State Medical University, Saratov Military Medical Institute, Saratov Institute of Social Education, Head of Centre of Medical and Social Research
Summary:

The article presents the results of studies of life quality of patients with ischemic heart disease and old myocardial infarction. The life quality is considered as an independent and objective multifactor indicator reflecting the status of this category of patients

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The investigation of cardiac neuropathy formation characteristics in patients with metabolic syndrome and carbohydrate metabolism malfunction (according to the data of cardiac rhythm variability analysis)

Summary:

Aims: To study the aspects of cardiac neuropathy (CN) early formation in patients with metabolic syndrome (MS) and carbohydrate metabolism malfunction according to the data of cardiac rhythm variability analysis (CRV). Vegetative status assessment in patients with MS and glucose tolerance disturbance (GTD), MS and type 2 diabetes mellitus (DM-2) has been done relying on the investigation of CRV analysis conventional features, such as RMSSD, pNN50, new approach application based on the determination of rhythmogram short period variations (RSPV), and rhythmogram weighted-mean variations (RWMV). RSPV monotony rise failure has been revealed on decrease of the heart contraction rate in patients with MS and GTD, MS and DM-2. Considerable decrease of RWMV has been observed in patients with MS and DM-2. RWMV values determined within 24 hours have been diminished in the morning in patients with MS and DM-2 and normal at night. RMSSD and pNN50 features have appeared to be significantly diminished in patients with MS and DM-2, they ranging within the normal readings in patients with MS and GTD, though in the morning pNN50 values have been found at the lower tolerance. Primary and completely reversible manifestations of CN have been revealed in patients with MS and GTD; new RWMV feature has been noted to have advantages over the conventional characteristics when diagnosing the signs of CN in patients with MS and GTD

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