Saratov JOURNAL of Medical and Scientific Research

Intense light deprivation as a factor in stress disorders of behavioral reactions and cognitive functions in the experiment

Year: 2019, volume 15 Issue: №2 Pages: 363-368
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Antipova O.N., Ivanov A.N., Zlobina O.V., Kirichuk V.F., Surovtseva K.A., Ankina V.D., Bondar G.D., Zenkina T.M., Polyukova M.V.
Organization: Saratov State Medical University

Objective: to study the efect of light desynchronosis on behavioral reactions and cognitive functions of white male rats. Material and Methods. The study was conducted on 36 intact non-pedigree white male rats, which were divided into 2 groups: experimental and control. Animals were exposed to artifcial illumination 24 hours a day provided by the fuorescent lamp of 60 kW capacity. The same animals of the experimental group on the 10th, 21st and 30th days were tested in the installations «Dark-light camera» and «Open feld». Results. On the 10th day of intensive light deprivation, the indicators refecting the research-orientation activity reached the maximum values, which indicated the development of stress damage to the animal organism. On the 21st day of the experiment, the

Keywords: pneumocysts

1 Kostenko EV, Manevich TM, Razumov NA. Desynchronosis as one of the most important factors of occurrence and development of cerebrovascular diseases. Medical case 2013; 2: 104–16
2 Zyrianov AI. On the application of standard time. Geographical Bulletin 2013; 1 (24): 13–7
3 Antipova ON, Zlobina OV, Kirichuk VF, et al. Stressful disorders of behavioral reactions of animals with intense light deprivation. Modern problems of science and education 2018; 4
4 Vinogradova IA. Comparative study of the infuence of diferent light modes on psychoemotional manifestations and motor activity in rats. Bulletin of NSU 2006; 4 (2): 69–77
5 Zlobina OV, Antipova ON, Rubizova AA et al. The infuence of light desynchronosis on behavioural responses in male rats. In: Scientifc forum: medicine, biology and chemistry: Collection of articles on the materials of VII International scientifc-practical conference. Moscow, 2017; p. 72–8
6 Osikov MV, Ogneva OI, Gizinger OA. It is a logical status and cognitive function in experimental desynchronosis under led lighting conditions. Fundamental research 2015; 1: 1392–6
7 Reznikova ZhI. Cognitive behavior of animals, its adaptive function and regularities of formation. Bulletin of NSU 2009; 3 (2): 53–67
8 Bakhtiiarova ShK, Kapysheva UN, Ablaikhanova NT, et al. Behavior in various tests. International journal of applied and fundamental research 2017; 8: 92–6
9 Sudakov SK, Nazarova GA, Alekseeva EV, et al. Determination of the level of anxiety in rats: the diferences between the results in the tests «Open feld», «Elevated cruciform labyrinth», and Vogel test. Bulletin of experimental biology and medicine 2013; 155 (3): 268–70
10 Periamkova AA, Eliseeva EV, Iuditskiy AD, et al. Behavioral reactions in experimental animals with diferent prognostic resistance to stress in the «Open feld» test. Biology. Earth Sciences 2013; 3: 83–91
11 Sarkisov GT, Sarkisian RSh, Karapetian LM, et al. Individual characteristics of mice behavior in the test «Dark- light camera». Biological journal of Armenia 2010; 1 (62): 22–9
12 Mayorov YuV. Evaluation of individual-typological features of behavior and stability of intact white male rats on the basis of factor model. Clinical Informatics and Telemedicine 2011; 7 (8): 21–32
13 Anisimov VN, et al. Light desynchronosis and the risk of malignant neoplasms in laboratory animals: the state of the problem. Oncology issues 2014; 60 (2): 15–27
14 Kravtsov OA, Antipova ON, Zlobina OV. Stress disorders of behavioral reactions of animals in the modeling of light desynchronosis. Scientifc publishing center «Actualnost. RF», 2018; p. 12–4.

2019_02_363-368.pdf339.96 KB

No votes yet