№1, 2008, volume 4

The article gives brief biographic information about professor P.S. Grigoriev, that highlights several aspects of his becoming a scientist and founder ofSaratovscientific schoolofdermatovenereology in the first halfofthe 20th century. The scientific inputofP.S. Grigoriev in the development of native and world-wide dermatovenereological science is also shown.

In article is given the review of a modern condition of a problem of the Reino phenomenon, its diagnostic and differential diagnostics meaning. 40 afflicted persons by a systemic scleroderma and systemic lupus erythematosus with clinically apparent Reino symptoms and - 40 practically healthy internship doctors as a control group were investigated. The given research has allowed to specify features of statement of со Id test and interpret its results, to reveal pathogenetic mechanisms of infringement of a hemodynamics, including early stages of development, and to develop the most rational approaches for treatment.

We studied the use ofnon-steroid anti-inflammatorydrugs (NSAID) at the in-patient department ofcentral district hospitalwith the application ofDDD-techniques before and after the formular system adoption. After introduction of drug formular and treatment standards the use of NSAID was reduced; the physicians began to use modern drugs. Non-indicated and contraindicated NSAID were prescribed more seldom. Itwas determined that reduction of antihypertensive drugs efficiency in hypertensive patients was the main side effect of NSAID use. NSAID gastropathy occurred more seldom, and mainly in the patients receiving several NSAIDs simultaneously.

Low-intensify electro-magnetic waves (EMW) influence were studied at experiment. Certain EMI frequency regimes (they are transparent for the water and water-binding substances, and they are known as trans-resonance) can intensify the metabolic rate. In turn, certain EMW frequency regimes (they are not transparent for the water and the water-containing tissues, and they are called as non-resonance) can disturb the native electro-magnetic status of the cells and can lead to morphological changes in organs. Morphological changes in adrenal glands and cortizol level of 60 White Vistar rats (males) in serum under transparent EMW frequency regimes and non-transparent ones were examined. Transparent and non-transparent frequency regimes impact the various changes in adrenals. Cortizol level corresponds to morphologic conclusion. Stress modified EMW-effects in both variants - under resonance and non-resonance EMW frequency regimes in adrenal morphology and cortizol level.

The article is devoted to some aspects of influence of digestive apparatus diseases (chronic gastritis, a stomach ulcer, chronic cholecystitis) on clinical course ofischemic heart disease. It is revealed, thatthe patients with clinical symptomatology are typically to have extra cardiac hue of painful heart attacks. The patients with influence ofischemic heartdisease and digestive apparatus disorders have sympathetic overbalance of the vegetative one against the background of the parasympathotonia.

The team of the first medico sanitary aid for population has examined the patients with ‘cardiac pain' (heavy heart) in the district of general practitioner. The physical diagnosis, parameters of psychological and social status were determined. The authors developed clinical recommendations to organization of diagnostics and interference.

The immobilization of broken fragments by two-jaw anchor splints in patients with the mandibular fractures in a combination with inflammatory diseases ofperiodontium usually causes the exacerbation and progression of the diseases and growing progressively worsening ofperiodontium status. The intensity of these conditions depends on an initial status ofperiodontal tissue. The posttraumatic suppurative inflammatory complications of the mandibular fractures frequency depending on the initial stage of periodontal disease are marked.

Smolensk State Medical Academy1 Saratov State Medical Univercity2
As the result of carried out investigation itwas revealed by the authors thatthe method oftreatment ofexacerbations of destructive form of chronic periodontitis based on active medicinal therapy with the use of combination of "Mepacyl” (Pierre Rolland) and “Nise"(nimesulide) allows to control inflammatory signs quickly and to reduce the number of visits to the dentist.

The authors of this article discuss advantages of conservative treatment’s complex of patients with serious malleolar fractures. Improvement oftreatment quality and reduction of labor disability period by means ofworked out new complex approach are revealed. All this is confirmed by tests of evident medicine using mathematical analysis and modelling.

The scientific research deals with the analysis of direct results of urgent operations of 81 patients with combined complications of ulcerous disease of stomach and duodenum. On the base of this research work it is possible to define the criteria which letto choose the optimal way of the operation in case of acute combined complications.