Saratov JOURNAL of Medical and Scientific Research

Kirillova T.V.

Saratov State Medical University n.a V. I. Razumovsky, Department of Dental and Maxillofacial Surgery, Post-graduate

Posmetnaya TV. Peculiarities of clinical and X-ray findings at women during postmenopause with chronic generalized periodontitis determined by mineral bone density

Year: 2016, volume 12 Issue: №4 Pages: 586-588
Heading: Stomatology Article type: Original article
Authors: Eremina N.V., Ismailova О.А., Strukov V.I., Kirillova T.V.,
Organization: Penza Institute for Advanced Training of Physicians
Summary:

The aim: to study clinical and X-ray specifics of chronic generalized periodontitis of women during a postmenopaus-al period determined by mineral bone density. Material and Methods. 80 women having chronic generalized periodontitis during a postmenopausal period were examined using clinical and X-ray research. Material of bone density was taken into consideration. Results. Decrease of hygienic indices of women at postmenopausal period has been found. It depends on the degree of severity of chronic generalized periodontitis. There was a reverse connection of periodon-tal index and mineral density of bone tissues in the 1-st group: — 0.9 (p<0.05), in the 2-nd group: — 0.5 (p<0.05), in the 3-rd group: — 0.79 (p<0.05). Cone-beam computer tomography made possible to find out the initial signs of edge osteoporosis of interdental partitions at the light degree of chronic generalized periodontitis and signs of spot and homogenous osteoporosis of gum bones, osteoporosis of interdental partitions with osteolysis at mild and severe degrees of severity. Conclusion. The clinical researches with cone-beam computer tomography and densitometry have revealed the exact data on the condition of bone tissues. The results have given an opportunity to plan osteotropic therapy and to control the dynamics of the process correctly.

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Biomechanical modelling of cerebral arteries at different variants of configuration of intracranial arteries of vertebrobasilar system

Year: 2016, volume 12 Issue: №2 Pages: 118-127
Heading: Macro- and Micromorphology Article type: Original article
Authors: Fomkina О.А., Ivanov D.V., Kirillova I.V., Nikolenko V.N.
Organization: Saratov State Medical University, Saratov state university
Summary:

The purpose is to consider the biomechanical modelling of cerebral arteries at different structural variants of intracranial arteries of vertebrobasilar system. Material and methods. By means of the system of the final and element analysis ANSYS on the basis of data on geometry, morphometricand biomechanical properties of cerebral arteries their biomechanical models have been constructed. On the received models for 9 structural variants of intracranial arteries of vertebrobasilar system, haemodynamic parameters and parameters of the intense deformed condition of walls of arteries have been analyzed. Results. The most frequent variant of a configuration of intracranial department of vertebrobasilar system is the combination of average in size of angles of connection of vertebrata and bifurcation of basilar arteries. Such option occurs in 49% of cases. More rare variant (1,5% of cases) with the narrow angles of connection of vertebrata and bifurcations of basilar arteries has been observed. The design of intracranial arteries of vertebrabasi-lar system exerts an impact on distribution of bloodflow and effective tension in a vascular wall of back brain arteries. Conclusion. According to the study it has been determined that the constructed individual biomechanical models may provide information on some parameters of haemodynamics and the intense deformed condition of a vascular wall which causes the development of atherosclerosis and intracranial aneurisms.

Peculiarities of clinical and immunological oral status in patients with lymphomas

Year: 2013, volume 9 Issue: №3 Pages: 428-431
Heading: Stomatology Article type:
Authors: Lepilin А.V., Kirillova Т.V., Erokina N.L.
Organization: Saratov State Medical University
Summary:

The aim of the work is to study clinical and immunological features of oral cavity state and cytokine status of oral fluid in patients with lymphomas before treatment against the background of receiving cytostatic drugs. Material and methods. 50 patients with initial diagnosis of lymphoma were examined. We measured clinical indicators of oral cavity state. The quantitative measures of immunoglobulins, lysozyme activity, cytokine status were investigated in patients with lymphoma. Results. The pathological changes in the mucous membrane, the current active inflammatory process in parodentium, high intensity decay, as well as abnormalities in the local reactivity system and cytokine disbalance were revealed. Conclusion. The performed dental studies proved the fact, that before treatment has been applied the patients have already had complicated dental status and marked imbalance in the local immune system of oral cavity. When polychemotherapy has been applied certain intensification of mucosal immunity abnormalities has appeared. It was determined by intensification of clinical symptoms in oral cavity.

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