Saratov JOURNAL of Medical and Scientific Research

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Anterior cerebral artery variants according to individually-typological and combined variabilities of its morphological and biomechanical features

Year: 2013, volume 9 Issue: №1 Pages: 28-33
Heading: Macro- and Micromorphology Article type: Original article
Authors: Fomkina О.A., Nikolenko V.N.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The purpose of the article is to define variants of anterior cerebral artery (АСА) of adults depending on typological and combined variability of its morphological and biomechanical features. Material and methods: The research has included 228 samples of anterior cerebral arteries, 115 corpses of people aged 21-84 years received on autopsy. The following points have been under the research: external and internal diameters, wall thickness, general strength, strength range, absolute and relative deformation of an artery. Results: According to the studied parameters 3 groups of variants of arteries have been allocated: with average size of a sign (M±s), with lesser size of a sign ( M + s). Combined variability of morphological and biomechanical features of АСА has been presented. Conclusion: АСА groups with higher variability, especially at men, have been observed in 2,2-2,6 times more often, than at women. As exception, thin-walled АСА which in 1,7 times more often taped at women have been considered. It has been revealed that subjects of alternative group III in 1,2-1,7 times older than those of alternative group I of arteries. Age of subjects who have been classified according to biomechanical parameters of АСА wall has been approximately identical (r=0,28-0,51). The experimentally received data about morphological, deforming and strengthening features may be of great value in studying of blood flow modeling and in optimization of intravascular interventions on cerebral arteries.

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Individual typological variability of macro-microscopical and biomechanical properties of intracranial part of vertebral artery

Year: 2012, volume 8 Issue: №4 Pages: 894-899
Heading: Macro- and Micromorphology Article type: Original article
Authors: Nikolenko V.N., Fomkina О.A.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The purpose of the study is to reveal the features of individual typological variability of macro-microscopical and biomechanical properties of the wall of intracranial part of vertebral arteries (IPVA) in adult people. Materials and methods: The research material of 228 samples of IPVA has been received by autopsy of 115 corpses of people aged 21-84 years. External diameter, thickness of the wall, diameter of lumen of artery have been measured. Biomechanical properties of IPVA have been studied by explosive carTira Test 28005 with a loading cell of 100 H. General strength (H), breaking point (H/mm2), Young»s modulus (H/mm2), absolute (mm) and relative deformation (%) of samples of arteries have been defined. Results: 3 groups of variants of arteries have been isolated: with average size of a sign (M±y), less than the average size (<M — y) and more than the average size (>M+ y). The conclusion: The obtained data about functional anatomy of vascular bed of brain may be useful in blood flow modeling and optimization of extra — and intravascular interventions.

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