Saratov JOURNAL of Medical and Scientific Research

Platonova A.N.

Saratov State Medical University n.a. V. I. Razumovsky, Department of Skin and Venereal Diseases, Candidate of Medical Science, Assistant

Endothelial dysfunction in psoriasis and type 2 diabetes in terms of comorbidity

Year: 2013, volume 9 Issue: №3 Pages: 590-595
Heading: Dermatovenerology Article type: Review
Authors: Slesarenko N.A., Utz S.R., Shtoda U.M., Platonova A.N.
Organization: Saratov State Medical University
Summary:

In the article the analysis of medical literature of changing in a vascular endothelium in psoriasis and type 2 diabetes in a combination is given.

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The characteristics of personality profile of patients with HIV-associated psoriasis

Year: 2013, volume 9 Issue: №3 Pages: 552-556
Heading: Dermatovenerology Article type: Original article
Authors: Morrison А.V., Utz S.R., Davydova А.V., Grishina V.B., Platonova A.N., Shtoda U.M.
Organization: Saratov State Medical University
Summary:

The goal: to give a characteristic of the personality profile, a comparative evaluation of psychosomatic changes in patients with psoriasis and HIV-associated psoriasis. Materials and methods. The study involved 27 patients aged
18-65 years with psoriasis and HIV-associated psoriasis, and isolated comorbid mental disorders and patients without skin disease, formed the control group. The survey in all patients was conducted with clinical-dermatological method, supplemented by psychometric methods (Hospital Anxiety and Depression Scale (HADS), the Hamilton Scale for Depression (HDRS)). Results. Analysis of the psychological status of patients with psoriasis demonstrated a high frequency of mental disorders in these patients.

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Side effects of systemic retinoid therapy in patients with severe psoriasis

Year: 2013, volume 9 Issue: №3 Pages: 549-552
Heading: Dermatovenerology Article type: Original article
Authors: Slesarenko N.A., Bakulev A.L., Shabogina A.A., Platonova A.N., Utz S.R., Markina M.V., Shtoda U.M.
Organization: Saratov State Medical University
Summary:

The aim: To determine the nature and frequency of side effects observed on acitretin therapy of patients with severe forms of psoriasis. Materials and methods. The study included 20 patients with generalized pustular psoriasis. Due to the inefficiency of the ongoing standard therapy, in addition to the plan of treatment, all patients were included systemic retinoid — acitretin (neotigazon) at a dose of 0,3-0,5 mg/kg per day. I control group consisted of patients with psoriasis receiving standard therapy without the use of systemic retinoids. II control group consisted of patients taking acitretin about keratosis. Results. In 18 patients of the main group noted the development of side effects, such as xerosis and nail fragility. In 14 patients of the main group and 3 patients of the II control group the results of urinalysis tests and Nechiporenko sample were detected by elevated levels of red blood cells and the development of hematuria. Conclusion. The study found that 17 patients had development of hematuria, which can be considered regarded as a side effect of acitretin therapy.

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Cases Sweet’s syndrome in dermatologist practice

Year: 2012, volume 8 Issue: №2 Pages: 633-637
Heading: Skin Diseases Article type:
Authors: Panina L.V., Shvidun D.V., Slesarenko N.A., Platonova A.N., Grashkina I.G., Gnilosyr O. A.
Organization: Saratov State Medical University
Summary:

The article presents cases of two patients which have Sweet’s syndrome, a rare form of dermatosis. The author summarizes data of etiology, pathogenesis and clinical presentation, and then provides differential diagnosis. Clinical observations of patients with Sweet’s syndrome and describes possible problems of diagnosis process are displayed.

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