Saratov JOURNAL of Medical and Scientific Research

Kondrateva N.N.

Saratov State Medical University n.a. V.I. Razumovsky Assistant of Department of Dermatovenerology and Cosmetology

The combined method of applying chitosan-con-taining hydrogel together with radiofrequency lifting

Year: 2018, volume 14 Issue: №4 Pages: 744-747
Heading: Dermatovenerology Article type: Original article
Authors: Galkina Е.М., /Utz S.R./ Kondrateva А.А., Karakaeva A.V., Artemenko S.A.
Organization: Saratov State Medical University
Summary:

Purpose: evaluation of Pelleve™ method ("Surgitron DF S5" device) effectiveness when combined with application of chitosan-based hydrogel. Material and Methods. A study of cosmetic chitosan-based hydrogel in combination with radiofrequency lifting in a group of patients consisting of 18 people aged 30 to 60 years. Results. With chitosan-containing hydrogel applied to the skin before the procedure of radiofrequency lifting, the skin is heated more quickly which effectively reduces working time of the electrode. Conclusion. The technical outcome of the study is an increased efficiency of radio wave lifting achieved through the use of chitosan-containing hydrogel.

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The effect of botulinum toxin type A injections on production of sebum in seborrhea

Year: 2018, volume 14 Issue: №4 Pages: 740-744
Heading: Dermatovenerology Article type: Original article
Authors: Kondrateva А.А., Galkina Е.М., Karakaeva A.V., Morrison A.V., Morrison V.V.
Organization: Saratov State Medical University
Summary:

 Aim: assessment of sebum production dynamics in patients who received treatment for mimic and static wrinkles in glabella and forehead regions with phase of a menstrual cycle taken into account. Material and Methods. We observed 15 female patients aged 24-38 years who received botulinum toxin therapy. Each BTX-Avial contained 100 units of lyophilized preparation. The solution of BTX-Awas prepared by mixing it with 2 ml of sterile saline. Five intramuscular injections with 2 U of BTX-A per point were made across the forehead, while 3 U injections were done in the glabellar area. The total amount of botulinum toxin used was 19 U per patient. Results. Maximum decrease in sebum production was observed 4 weeks after botulinum toxin injections, and return to baseline was observed at 16 weeks of follow-up. Conclusion. According to the obtained data, it may be stated that botulinum toxin injections affect sebum production with a maximum decrease observed at 4 weeks after botulinum toxin therapy.

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Urticarial vasculitis

Year: 2013, volume 9 Issue: №3 Pages: 585-589
Heading: Dermatovenerology Article type: Case report
Authors: Kondrateva N.N., Utz S.R., Galkina E.M., Roshchepkin V.V.
Organization: Saratov State Medical University
Summary:

The literature review and clinical case of urticarial vasculitis is presented in the article.

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Effciency and safety of the use of long-wave UVA-1 phototherapy in treatment of psoriasis

Year: 2012, volume 8 Issue: №2 Pages: 637-639
Heading: Skin Diseases Article type: Original article
Authors: Rasskazov Y.A., Kondratyeva N.N., Bakulev A.L.
Organization: Saratov State Medical University
Summary:

The effectiveness of the long wavelength ultraviolet therapy (UVA-1) in complex treatment of patients with psoriasis has been studied during the research. There 20 patients with moderately severe and severe psoriasis in the phase of progressive dermatosis have been observed. The therapy was organized using photobox Waldmann UV-7001K (Herbert Waldmann GmbH & Co, Germany) and F85 100W-TL10R lamps, creating radiation spectrum of UVA-1 (ƛ = 340 – 400 nm) and emission maximum was ƛ=370 nm. 20 patients of the comparison group receive standard therapy in combination with PUVA therapy. The group did not differ from the main group of patients in age, duration and form of the disease. The effectiveness of the treatment was measured according to the dynamic assessment of PASI index. The usage of a long wavelength ultraviolet therapy (UVA-1) has caused a reduction of the severity and the extent of skin lesions, gave positive outcomes in all patients of the study. No adverse effects caused by the therapy undertaken have been noted. The administration of long wavelength ultraviolet therapy (UVA-1) is safe and effective in patients with psoriasis.

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Clinical case PAPA-syndrome (pyogenic arthritis, pyoderma gangrenosum, acne conglobata

Year: 2012, volume 8 Issue: №2 Pages: 630-633
Heading: Skin Diseases Article type:
Authors: Kondratyeva N.N., Gnilosyr O.A., Slesarenko N.A., Reshetnikova E.M., Epifanova A.Y., Shvidun D.V.
Organization: Saratov State Medical University
Summary:

The study presents a relatively rare case of dermatosis. It is PAPA syndrome in a 23 years-old female patient which is inherited as an autosomal dominant mode. The data about the etiology, pathogenesis, clinical picture were summarized, differential diagnosis was led. Problems with the treatment of the disease have been showed.

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Effciency of narrowband medium wave (UVB) phototherapy in combination with cytostatic therapy in psoriasis

Year: 2012, volume 8 Issue: №2 Pages: 627-630
Heading: Skin Diseases Article type: Original article
Authors: КKondratyeva N.N., Rasskazov Y.A, Bakulev A.L.
Organization: Saratov State Medical University
Summary:

The study presents the results of combined usage of narrowband UVB phototherapy with low — dose methotrexate in treatment of psoriasis. 48 patients with moderately severe and severe psoriasis in the phase of progression accompanied by psoriatic arthritis have been observed. 30 patients were treated with UVB therapy with a 311 nm narrowband in combination with low doses of methotrexate (7.5 mg per week). Photobox Waldmann 7002 K (Germany) with TL-01 lamps which generate radiation in 310 – 315 nm wavelength range with maximum 311 nm wavelength emission. The procedures have been carried out 4 times a week. Methotrexate should be received as tours 7.5 mg once a week, according to Weinstein — Frost scheme under the supervision of laboratory parameters. The treatment course consists of three tours. Treatment has been carried out on a background of traditional therapy.The comparison group received conventional therapy in combination with narrowband UVB phototherapy and nonsteroidal anti-infammatory drugs. Evaluation of the effectiveness of the therapy was based upon dynamic assessment of PASI and DLQI indexes and proved by earlier reduction of clinical symptoms than in the comparison group, which resulted in reduction of absolute PASI and DLQI values. No adverse effects caused by the therapy undertaken have been noted. The results of the study appear to prove safety and effectiveness of such therapy in treatment of psoriasis.

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