Saratov JOURNAL of Medical and Scientific Research

Galkina E.M.

Saratov State Medical University n.a. V. I. Razumovsky, Department of Skin and Venereal Diseases, Assistant

The combined method of applying chitosan-con-taining hydrogel together with radiofrequency lifting

Year: 2018, volume 14 Issue: №4 Pages: 744-747
Heading: Dermatovenerology Article type: Original article
Authors: Galkina Е.М., /Utz S.R./ Kondrateva А.А., Karakaeva A.V., Artemenko S.A.
Organization: Saratov State Medical University
Summary:

Purpose: evaluation of Pelleve™ method ("Surgitron DF S5" device) effectiveness when combined with application of chitosan-based hydrogel. Material and Methods. A study of cosmetic chitosan-based hydrogel in combination with radiofrequency lifting in a group of patients consisting of 18 people aged 30 to 60 years. Results. With chitosan-containing hydrogel applied to the skin before the procedure of radiofrequency lifting, the skin is heated more quickly which effectively reduces working time of the electrode. Conclusion. The technical outcome of the study is an increased efficiency of radio wave lifting achieved through the use of chitosan-containing hydrogel.

AttachmentSize
2018_4-1_744-747.pdf393.53 KB

The effect of botulinum toxin type A injections on production of sebum in seborrhea

Year: 2018, volume 14 Issue: №4 Pages: 740-744
Heading: Dermatovenerology Article type: Original article
Authors: Kondrateva А.А., Galkina Е.М., Karakaeva A.V., Morrison A.V., Morrison V.V.
Organization: Saratov State Medical University
Summary:

 Aim: assessment of sebum production dynamics in patients who received treatment for mimic and static wrinkles in glabella and forehead regions with phase of a menstrual cycle taken into account. Material and Methods. We observed 15 female patients aged 24-38 years who received botulinum toxin therapy. Each BTX-Avial contained 100 units of lyophilized preparation. The solution of BTX-Awas prepared by mixing it with 2 ml of sterile saline. Five intramuscular injections with 2 U of BTX-A per point were made across the forehead, while 3 U injections were done in the glabellar area. The total amount of botulinum toxin used was 19 U per patient. Results. Maximum decrease in sebum production was observed 4 weeks after botulinum toxin injections, and return to baseline was observed at 16 weeks of follow-up. Conclusion. According to the obtained data, it may be stated that botulinum toxin injections affect sebum production with a maximum decrease observed at 4 weeks after botulinum toxin therapy.

AttachmentSize
2018_4-1_740-744.pdf353.29 KB

Dynamics of some biophysical parameters of skin under the influence of chitosan-containing hydrogel.

Year: 2017, volume 13 Issue: №3 Pages: 616-620
Heading: Dermatovenerology Article type: Original article
Authors: Galkina Е.М., Shipovskaya А.В., Gegel' N.O., Artemenko S.A., Utz S.R.
Organization: Akripol LLC, Saratov State Medical University, Saratov state university
Summary:

Objective: to conduct a clinical study of the effectiveness of the gel based on chitosan in skin care healthy people with different manifestations of signs of aging and patients with pigmented lesions of the skin of those aged 34 to 63 years. Material and Methods. The study was performed in the group of patients consisting of 10 people ranging in age from 34 to 63 years. They have been estimated by the following biophysical parameters: the moisture level and elasticity of the skin, the melanin content, the level of erythema, as well as the width and depth of wrinkles. Results. The application of hydrogel with chitosan marked hydration of the skin (in particular immediate increase in skin moisture immediately afterthe first application), reducing the depth and width of wrinkles, restoring elasticity and improving muscle tone. Conclusion. Course application of the hydrogel during the month allows you to obtain a lasting effect, OMO application.

AttachmentSize
2017_03-1_616-621.pdf1.15 MB

Pityriasis rubra pilaris (Devergie's disease): clinical case

Year: 2016, volume 12 Issue: №3 Pages: 504-509
Heading: Dermatovenerology Article type: Case report
Authors: Galkina ЕМ, Utz SR, BakulevAL, Minyonok ТА.
Organization: Saratov State Medical University
Summary:

Pityriasis rubra pilaris (Devergie's disease) is a rare chronic papulosquamous skin disease, it is of unknown etiology, leading to palmoplantar keratoderma, erythroderma and ectropion. Due to its rarity and difficulty in differentiating it with psoriasis, we are presenting our own observations and diagnostcis. We present a patient with a classical type 1 iasis rubra pilaris of a type I, whose condition improved significantly after treatment with systemic aromatic retinoids.

AttachmentSize
2016_03-1_504-509.pdf1.63 MB

Гравюры Уильяма Хогарта из коллекции Саратовского государственного художественного музея имени А. Н. Радищева, иллюстрирующие проявления сифилиса

Year: 2015, volume 11 Issue: №3 Pages: 486-491
Heading: Dermatovenerology Article type: Author's opinion
Authors: Утц С.Р., Шерстнева В.Н., Галкина Е.М., Персати М.А, Пашкова Л.В.
Organization: Saratov State Medical University, Saratov State Art Museum n.a. A.N. Radishchev
Summary:

Статья является продолжением предыдущей работы, в которой были изложены данные о связи дерматовенерологии с изобразительным искусством на примерах нескольких художественных полотен европейской и русской живописи из фонда Саратовского государственного художественного музея имени А. Н. Радищева. В настоящей работе рассматривается серия гравюр «Карьера проститутки» Уильяма Хогарта из коллекции этого музея, отражающая различные проявления сифилитической инфекции как результат пороков социально больного аристократического общества.

AttachmentSize
2015_03-01_486-491.pdf5.58 MB

Benefits of optical coherence tomography for imaging of skin diseases

Year: 2015, volume 11 Issue: №3 Pages: 392-396
Heading: Dermatovenerology Article type: Short message
Authors: Utz S.R., Zimnyakov D.A., Galkina E.M., Yuvchenko S.A., Alonova I.V., Artemina E.M., Ushakova O.V.
Organization: Saratov State Medical University, Saratov State Technical University n.a. Yu.A. Gagarin
Summary:

Aim: working out the methods of visualization of information obtained during optical coherent tomography in normal skin and in series of inflammatory disorders. Materials and Methods. OCS1300SS (made in Thorlabs, USA) was used in which the source of emission of radiation was a super-luminiscent diode with mean wavelength of 1325 nm. 12 patients with different skin conditions and 5 virtually healthy volunteers were examined with ОСТ procedure in OPD and IPD settings. High resolution USG numerical system DUB (TPM GmbH, Germany) was used for comparative USG assessment. Results. ОСТ demonstrated considerably more detailed picture of the objects scanned compared to USG investigation. Image obtained with the help of ОСТ contains vital information about sizes of macro-morphological elements, status of vascular elements and their density in different depths of the skin. Conclusion. Additional results obtained from ОСТ of the skin lesions in plane section improves attraction for ОСТ in practical dermatology.

AttachmentSize
2015_03-01_392-396.pdf1.45 MB

Low coherence re-flectometry of skin: benefits for skin imaging

Year: 2015, volume 11 Issue: №3 Pages: 376-380
Heading: Dermatovenerology Article type: Short message
Authors: Zimnyakov D.A., Utz S.R., Galkina E.M., Yuvchenko S.A., Alonova I.V., Artemina E.M., Ushakova O.V.
Organization: Saratov State Medical University, Saratov State Technical University n.a. Yu.A. Gagarin
Summary:

Goal: to examine the effectiveness of use low coherent reflectometry method for diagnostic purposes in clinical dermatology. Materials and methods. For measurements optical coherence tomography OCS1300SS (Thorlab, USA) with swiped frequency was used. 12 patients with different skin diseases were studied (psoriasis, acne, scleroderma, etc.). Results. Distinct border was detected between layers with different optical characteristics (and structure) at a depth of 1000 m to 2000 microns for majority of the samples studied. It is important to note that a good regerneration of distribution of the interference signal during transmission from one section to another and close to an exponential decay of signal with an increase in depth of probing. Conclusion. As a criterion of pathological changes,may be proposed the degree of spatial uniformity in distribution decay constant of interference signal in depth obtained with help of low coherent reflectometry (in vivo).

AttachmentSize
2015_03-01_376-380.pdf781.13 KB

Skin and venereal diseases in some artworks of Saratov State Art Museum named after A. N. Radishev

Year: 2014, volume 10 Issue: №3 Pages: 568-574
Heading: Skin Diseases Article type: Author's opinion
Authors: Utz S.R., Sherstneva V.N., Pashkova L.V., Galkina E.M., Persashvili M.A.
Organization: Saratov State Medical University, Saratov State Art Museum n.a. A.N. Radishchev
Summary:

In this article we discuss the relation between dermato-venereology and art on examples of some European and Russian paintings from Saratov State Art Museum named after A.N. Radishev. Features of artistic way of depiction cutaneous disorders in different historical periods are presented. Acquaintance with similar works of «artistic diagnostics» may be used in studying process and has cognitive, educational and social value.

AttachmentSize
2014_03-01_568-574.pdf6.55 MB

Noninvasive evaluation of the barrier properties of the skin

Year: 2014, volume 10 Issue: №3 Pages: 512-517
Heading: Skin Diseases Article type: Review
Authors: Utz S.R., Karakaeva A.V., Galkina E.M.
Organization: Saratov State Medical University
Summary:

Skin as an organ of protection covers the body and accomplishes multiple defensive functions. The intact skin represents a barrier to the uncontrolled loss of water, proteins, and plasma components from the organism. Due to its complex structure, the epidermal barrier with its major component, stratum corneum, is the rate-limiting unit for the penetration of exogenous substances through the skin. The epidermal barrier is not a static structure. The permeability barrier status can be modified by different external and internal factors such as climate, physical stressors, and a number of skin and systemic diseases. Today, different non-invasive approaches are used to monitor the skin barrier physical properties in vivo. The quantification of parameters such as transepidermal water loss, stratum corneum hydration, and skin surface acidity is essential for the integral evaluation of the epidermal barrier status. This paper will allow the readership to get acquainted with the non-invasive, in vivo methods for the investigation of the skin barrier.

AttachmentSize
2014_03-01_512-517.pdf364.59 KB

Urticarial vasculitis

Year: 2013, volume 9 Issue: №3 Pages: 585-589
Heading: Dermatovenerology Article type: Case report
Authors: Kondrateva N.N., Utz S.R., Galkina E.M., Roshchepkin V.V.
Organization: Saratov State Medical University
Summary:

The literature review and clinical case of urticarial vasculitis is presented in the article.

AttachmentSize
2013-03_1-585-589.pdf1006.71 KB