Saratov JOURNAL of Medical and Scientific Research

Chekhonatsky V.A.

Russian Medical Academy of Post-graduate Education, Resident of Department of Neurosurgery

Possibility of frameless biopsy of deep and remote brain tumors and impact of its results on treatment strategy

Year: 2019, volume 15 Issue: №2 Pages: 312-317
Heading: neurosurgery Article type: Original article
Authors: Shabunin A.V., Gorozhanin A.V., Vakatov D.V., Shestakov A.A., Chekhonatsky V.A.
Organization: Clinical Hospital n. a. S. P. Botkin
Summary:

Purpose: to assess the possibilities of frameless biopsy of brain tumors with deep and hard-to-reach localization and its impact on the treatment strategy. Material and Methods. 56 patients with supratentorial brain tumors of deep and hard-to-reach localization who underwent biopsy using frameless neuronavigation according to accepted standards. Results. In 9 (16.1 %) cases there was a discrepancy between the data of the preliminary MRI examination and the histological conclusion of the punctate after the biopsy, which changed the tactics of treatment. Conclusion. Biopsy of brain tumors of deep and hard-to-reach localization allows you to accurately and least invasive to establish the correct diagnosis. Conducting a frameless biopsy with subsequent immunohistochemical verifcation of the biopsy allows planning adequate further treatment, increasing the duration and quality of life of patients with brain tumors of deep and hard-to-reach localization.

Keywords: treatment
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Ultrasonic Dopplerometry in diagnosis of cervical injury in birth process

Year: 2017, volume 13 Issue: №1 Pages: 047-050
Heading: Radiology Article type: Original article
Authors: Chekhonatskaya M.L., Bakhmach V.O., Zabozlaev F.G., Chekhonatsky V.A.
Organization: Russian Medical Academy of Post-graduate Education, Saratov State Medical University
Summary:

The goal was to carry out the comparative analysis of ultrasonic Doppler indices and data of morphometric methods of uterine cervix examination of women with prenatal moving of amniotic fluid depending on presence or absence of uterine cervix trauma in labor. Material and methods. 148 pregnant women with prenatal moving of amniotic fluid were examined. The main group included 64 pregnant women with uterine cervix ruptures; the comparison group consisted of 84 patients without any labor trauma. Ultrasonic and morphological examinations of uterine cervix were carried out. Results. Cavernous transformation of venous cervical bloodstream closely correlated (r = 0,67, p <0.001) with the index of vascularization degree and labortrauma degree. Conclusion. The revealed echomorphological relationship in uterine cervix of pregnant women with various labor outcomes allowed using these data to predict uterine cervix rupture in labor process.

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Chronobiological aspects of changes in straight electro stimulation of spinal cord for treatment of neurological complications of cervical vertebrae osteochondro-sis

Year: 2012, volume 8 Issue: №2 Pages: 547-552
Heading: Neurology Article type: Original article
Authors: Chekhonatsky A.A., Korshunova G.A., Ovsyannikov D.M., Chekhonatsky V.A.
Organization: Saratov State Medical University
Summary:

Research Goal was to study infuence of treatment seance time, disease duration, and age on effcacy of straight electrostimulation of spinal cord. Materials. Biorhythmological characteristics of optimal time choice for electrostimula-tion séance were studied based on the sample of 32 patients with cervical osteochondrosis, who were subjected to paracentetic electrodes placement on posterior part of spinal cord. Results. Group of patients used morning séance, demonstrated change of clinical manifestations severity in accordance to JOA scale from 8,4±0,2 to 12,8±0,3 points that formed 46,6 %. Séance during daylight hours helped to decrease clinical manifestations severity by 25,1 %; evening séance promoted reduction by 22,1 %. In patients under 40 the average percentage of decrease of posttreatment neurological symptomatology consisted 83,6±3,6 %, in patients aged 60 and upwards this index was 74,6±3,2 %. Decrease of myelopathy severity was marked in the following way: 1 – 4 years of disease duration — by 73,6±4,8 %, more than 10 years — 63,7±2,1 %; estimation was carried out using JOA scale. Conclusion. Maximum effect of straight elec-trostimulation of spinal cord was observed in the morning hours. Clinical effect of isolated use of straight electrostimula-tion of spinal cord in the complex of treating neurological symptoms of cervical vertebrae osteochondrosis decreases while disease duration extends. Effect of electrostimulation reduces in accordance with patients’ age; maximum positive results of this method can be achieved in 1 – 4 years of disease duration.

Keywords: -
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