Saratov JOURNAL of Medical and Scientific Research

quality of life

Effectiveness of neure-protective therapy in patients with glaucoma

Year: 2018, volume 14 Issue: №4 Pages: 828-831
Heading: Ophtalmology Article type: Case report
Authors: Aprelev А.Е., Barbos Yu.A., Mukhanko I.Zh., Cherednichenko N.L., Abdulgazizova Z.F., Kataganova A.A., Bernovskaya A.A.
Organization: Mineralovodsky district hospital, Orenburg Regional Clinical Hospital, Orenburg State Medical University, Regional Clinical Diagnostic Center in Stavropol City, Stavropol Regional Clinical Hospital, Stavropol State Medical University

The results of clinical evaluation of three patients who were included in the multicenter study of the
effectiveness of neuroprotective treatment and its impact on the quality of life of patients with POAG are
presented in the article. Dynamics of visual acuity, intraocular pressure, total visual fields, photostress
test, contrast sensitivity and quality of life (according to the NEIVFQ-25 questionnaire) in patients
treated with neuroprotective study drug with 10 intramuscular injections administered 5mg once a day
are presented. Data on the improvement of visual functions and quality of life in patients with Stage I, II
and III of POAG who had undergone treatment with the study drug are demonstrated.

Keywords: quality of life
2018_4-2_828-831.pdf261.13 KB

Modern domestic cosmetics in combined treatment of scalp conditions

Year: 2018, volume 14 Issue: №4 Pages: 769-773
Heading: Dermatovenerology Article type: Original article
Authors: Shnaider D.A., Guskova O.P., Gorbenko A.V., Ivanov S.D.
Organization: Saratov State Medical University

Objective: to evaluate effectiveness, safety and feasibility of using modern domestic ASD-containing liposomal cosmetics (all type shampoo and balm for dry scalp) in combined treatment of psoriasis patients with scalp involvement. Material and Methods. Sixty three patients (35 women and 28 men) with disseminated guttate-plaque psoriasis with scalp involvement were observed in Saratov Regional Clinical Dermatovenerologic Dispensary. The disease was in the stage of progression in all patients. All type shampoo and balm for dry scalp were included in the treatment regimen of all patients, while no other topical preparations were used on the scalp. Results. We observed good therapeutic and cosmetic effect in all patients, who encountered noside effects during the use of ASD-containing liposomal cosmetics. Conclusion. Combined scalp skin care with the use of modern domestic ASD-containing cosmetics will help doctor and patient to achieve the optimal result in treatment of psoriasis with scalp involvement, effectively eliminating main symptoms of the disease in a shorter time, improving patients' quality of life and giving them opportunity to lead normal life and feel comfortable in society.

2018_4-1_769-773.pdf1.49 MB

Comparative analysis of the quality of life before and after various methods of invasive treatment of esophageal cancer

Year: 2018, volume 14 Issue: №3 Pages: 408-411
Heading: Surgery Article type: Original article
Authors: Tolstokorov A.S., Ramazanov E.N., Dergunova S.A.
Organization: Saratov State Medical University

The aim of the work is to assess the quality of life before and after multistage and one-stage operations, palliative interventions performed with malignant neoplasms of the esophagus. Material and Methods. The quality of life was evaluated in 565 patients with esophageal cancer at various stages of surgical treatment by means of questionnaires for assessing the quality of life of GIQLI, GSRS, MOS SF-36 questionnaire. Results. When performing multi-stage operations before the end of treatment, the quality of life changes insignificantly, and is comparable with the quality of life after palliative operations. The study of the quality of life after the end of treatment with the use of endoscopic minimally invasive technologies in these questionnaires convincingly showed the advantage of this category of surgical interventions due to less trauma, better cosmetic effect, quick activation and rehabilitation in the postoperative period. Conclusion. Taking into account the results of the research, preference is given to one-stage operations with the use of minimally invasive endoscopic techniques, which in a short time can save the patient from cancer and significantly improve the quality of life.

2018_3_408-411.pdf302.47 KB

Use of the scale of clinical expression of the stroke for determining the rehabilitation prediction

Year: 2018, volume 14 Issue: №1 Pages: 161-164
Heading: Neurology Article type: Original article
Authors: Repina L.A., Romanova T.V., Poverennova I.E.
Organization: Samara State Medical University

The aim is to study the relationship between the parameters of neurological status and quality of life of patients who first underwent ischemic strokes in the carotid basin to predict the outcome of an acute cerebrovascular accident. Material and Methods. 73 patients with ischemic stroke in the carotid artery basin were examined. Analyzed indices of the scales, reflecting the severity of motor deficit (NIHSS, Rankin, Rivermead, Fugl-Meyer), the initial evaluation and parameters of quality of life using the questionnaire SF-3624-36 months after inpatient treatment. Patients were divided into groups of favorable and unfavorable outcome according to the questionnaire SF-36. Results. A direct correlation between the level of physical and psychological health and indicators Of the Fugl-Meyer scale and a negative correlation between the level of psychological health and the severity of stroke on the NIHSS scale in a group with an adverse outcome was revealed. Conclusion. Indicators scales Fugl-Meyer, and NIHSS obtained in the acute period of ischemic stroke can be used to build a predictive model of outcome of stroke.

2018_01-1_161-164.pdf254.22 KB

Sclerosurgical and surgical treatment of patients with lower extremity varicose vein disease: analysis of results in a long-term period of observation

Year: 2017, volume 13 Issue: №4 Pages: 839-845
Heading: Surgery Article type: Original article
Authors: Gafurova D.R., Kulikova A.N., Chabbarov R.G., Pyatnitsky A.G.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University, Saratov «Omega-clinic»

Aim: to analyze and evaluate the long-term results of sclerosurgical and surgical treatment of patients with lower extremity varicose vein disease (VVD). Material and Methods. Diagnostics and treatment findings of 228 patients are presented. The main group consists of 153 patients (189 extremities) after intraoperative trunk catheter sclerotherapy of the great saphenous vein (GSV) with a crossectomy. The comparison group consists of 75 patients (96 extremities) after the GSV phlebectomy by Babcock — Narat. Long-term results (5-9 years) of treatment were evaluated by comparing the quality of life (QL) parameters of patients, the ultrasonic characteristics of venous bed for operated extremities, and the progression of VVD. Results. There was not found any considerable differences in respondents' QL during the comparison. Duplex ultrasound scanning of the lower extremities in most cases revealed a wide spectrum of pathological ultrasound signs (6 of 13 signs, the differences in which are statistically significant, but not specific for stem sclerotherapy and phlebectomy). Investigation of VVD dynamics after correction of the varicose syndrome revealed three variants of the disease course: regression, lack of dynamics, progression. Conclusion. The effectiveness of sclerosurgical interference in the long-term observation period is comparable with the surgical one, which is confirmed by the total number of positive (good and satisfactory) treatment results after using both methods (93.7 and 81.3% respectively), ultrasound diagnosis results, absence of significant differences in QL of patients.

2017_04_839-845.pdf1.31 MB

Interdisciplinary aspects of rehabilitation of patients with oncological diseases in non-terminal situation of the disease

Year: 2017, volume 13 Issue: №4 Pages: 806-808
Heading: Health Service Organization Article type: Review
Authors: Shmerkevich А.В., Vodolagin A.V., Balakina D.D.
Organization: Saratov State Medical University

Medical social rehabilitation of patients with oncological diseases in the non-terminal stage of the disease is based on the principle of an interdisciplinary approach, which involves complex special treatment, providing patients and their families with various types of social and psychological support at all stages of specialized care. The authors of the review consider the solution of medical and social problems in the rehabilitation of patients with oncological diseases in the context of the synergistic effect. Weak social and psychological protection of patients with oncological pathology adversely affects the prognosis of the disease and worsens patients quality of life. The review provides evidence that patients who receive social support are best adapted to the cancer situation, while a lack of social support is a significant risk factor for increased mortality in cancer patients.

Keywords: quality of life
2017_04_806-808.pdf225.19 KB

Quality of life and health risk factors in officers departed from Armed Forces

Year: 2017, volume 13 Issue: №3 Pages: 791-795
Heading: Health Service Organization Article type: Original article
Authors: Konovalov О.Е., Breusov A.V., Popov A.V, Breusov R.A.
Organization: Peoples' Friendship University of Russia

Objective: assessment of quality of life, identify of health risk factors for officers discharged from the Armed Forces, and development of step-by-step system for medical and social assistance to reserve soldiers (retired). Material and Methods. Anonymous questioning of 358 officers in different time periods, including the last year of service before departure, with the subsequent processing of the data using the statistical program SPSS. Results. It was established that the highest indicators of quality of life were from the military in reserve (RET.) more than 3 years, and the lowest from the military a year before the departure from the Armed Forces and in the first year after the departure. Conclusion. The authors proposed a step system of health and social care for members of the military reserve (retired) and an algorithm for its implementation, including regulations of interdepartmental interaction and integration of all organizations providing medical care.

2017_04_791-795.pdf399.65 KB

The dynamics of patients' life quality indices under the conditions of two-stage knee joint replacement

Year: 2017, volume 13 Issue: №3 Pages: 768-772
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Shpinyak S.P., Fedonnikov A.S., Barabash А.Р., Barabash Ju.A.

 The aim: to analyze the changes in the life quality indices of the patients with deep periprosthetic joint infection of the knee under the two-stage surgical treatment. Material and Methods. 57 patients who underwent two-stage revision-ary treatment in Research Institute of Traumatology, Orthopedics and Neurosurgery were interviewed with life quality questionnaire Short Form Medical Outcomes Study (SF 36 v.1). Interview results were compared with standardized population indices of SF-36 scales for males and females. Results. In all groups regardless of sex there was a general tendency for an increase in physical and psychological health component up to mean population values after the first stage of surgery and further growth after the second stage. Rehabilitation potential of psychomotor health was higher in women than in men. The ability to handle stress was lower in direct ratio with the patients' age. Conclusion. Two-stage reendoprosthetic treatment with articulating antimicrobial spacer implantation having high grade of fixation is an effective treatment method for deep periprosthetic infection which increases physical health and improves social functioning of patients.

2017_03-2_768-772.pdf1.16 MB

Social self-esteem: theoretical and methodological approaches to research


The perspective of the analysis of the phenomenon of the social well-being of patients with chronic diseases from the standpoint of the sociology of medicine is proved. Modern approaches to the study of social well-being within the framework of sociological and psychological approaches are singled out. The importance of studying the levels of social well-being (institutional and individual) is presented to explain the individual's chosen strategies of behavior in the disease situation. The vectors of operationalization of the category of social well-being within the sociology of medicine are indicated.

2017_03_554-559.pdf282.76 KB

The value of assessment of quality of life in realisation of medico-social rehabilitation of children-orphans in conditions of illness

Year: 2017, volume 13 Issue: №2 Pages: 288-291
Heading: Sociology of Medicine Article type:
Authors: Dubrovina M.S., Krom I.L., Chizhova V.M.
Organization: Saratov State Medical University, Volgograd State Medical University

Purpose: interdisciplinary analysis of quality of life and objectifying strategies of medico-social rehabilitation of children-orphans in conditions of illness. Material and Methods. Included in the study on a random sample of 354 respondents aged 14-18 years of age (160 males and 194 female). The study of quality of life was conducted using the international questionnaire of WHOQOL-100. Statistical significance of differences of average indices of life quality of groups of respondents was determined by non-parametric Mann —Whitney test. Results. Analysis of the averages of quality of life in the group of clinically healthy respondents were allowed to define the indices on average significantly (p<0.01 — p<0.05) different in the group of children-orphans and children living in families. During the research it was found that the average quality of life of orphans in a situation of a disease in most points of questionnaire were significantly lower than in the control group. Statistically significant differences of average values of indicators of quality of life in the analysis of the quality of life of the respondents (orphans and children living in families) in the case of illness related to the effects of disease and child abandonment, somatically and socially determined. Conclusion. Established in the course of the study the statistical relationship between indicators of quality of life from disease and the effectiveness of re-socialization proves the possibility of the objectification of recovery strategies and the formation of personally identifiable medical and social assistance to children-orphans in conditions of illness.

2017_02_288-291.pdf234.17 KB