Saratov JOURNAL of Medical and Scientific Research


Features of neurological and neuropsychological changes in the initial stages of encephalopathy in patients with idiopathic epilepsy

Year: 2011, volume 7 Issue: №4 Pages: 870-874
Heading: Neurology Article type: Original article
Authors: Burdakov V.V. Gumalatova N.V.
Organization: Orenburg State Medical University, Municipal health clinic Municipal Clinical Hospital № 3, Orenburg

Aim. The study was undertaken to identify the features of neurological and cognitive changes in idiopathic epilepsy based on neurological and neuropsychological research. Methods. A total of 105 patients with idiopathic epilepsy at the age of 16 to 45 years. In orderto identify features neuropsychological disturbances, all patients were systematized by the nature and frequency of seizures. Results. As a result of the work identified major the nature neurological and neuropsychological symptoms and syndromes of primary stages of encephalopathy in patients with idiopathic epilepsy

201104_870-874.pdf328.82 KB

Mechanisms of the damage and morphological changes in nervous system in case of electrical trauma

Year: 2010, volume 6 Issue: №2 Pages: 374-377
Heading: Neurology Article type: Review
Authors: A.E. Khrulev, V.N. Grigorieva, S.E. Khrulev
Organization: N. Novgorod State Medical Academy, N. Novgorod Scientific Research Institute of Traumatology and Orthopedics

The literary data analysis, permitting to characterize the mechanisms of the damage and morphological changes in nervous system in case of electrical trauma, is presented. A role of electrical current injury in a development of neurological pathology is regarded in detail

201002_374_377.pdf331.27 KB

Clinicodiagnostic value of functional morphological changes of intestine in encephalopathy development in cirrhosis

Year: 2010, volume 6 Issue: №2 Pages: 365-369
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: V.V. Ovsyannikova, I.V. Kozlova
Organization: Saratov State Medical University

The aim of the article is to study frequency and expressiveness of clinico-morphological and dysbiotic intestinal changes in cirrhosis and to estimate its interrelation with manifestations of hepatic encephalopathy. 146 patients with cirrhosis ages 20 to 70 years have been examined. The cirrhosis has been verified by standard methods. Examina¬tion included colonoscopy and stool specimen. Diagnostics of hepatic encephalopathy was based on clinical and psychometric methods. It is established that symptoms of intestinal dyspepsia often occurred in patients with cirrhosis of classes В and С by Chaild-Pugh. According to the endoscopic examination lesions of mucous membrane of large intestine have been revealed in 82% of patients with liver cirrhosis. Morphological research revealed changes in 100% of patients with cirrhosis. Frequency and expressiveness of changes in mucous membrane of large intestine depended on the degree of cirrhosis decompensation. Changes of biocenosis of large intestine were revealed in 93% of patients with cirrhosis, hepatic encephalopathy was diagnosed in 88% of patients, more frequently hepatic encephalopathy of stage I. The cirrhosis is accompanied by structural and functional changes of intestine that make up additional risk factor of development of hepatic encephalopathy

201002_365_369.pdf391.85 KB


Year: 2008, volume 4 Issue: №1 Pages: 88-92
Heading: Neurology Article type: Original article
Authors: I.E. Poverennova, E.V. Sevastyanova
Organization: Samara State Medical University

The questions of diagnostics and classification of cognitive disturbances in 112 patients with hypertensive encephalopathy are considered. The diagnosis of cognitive frustration was based on results of expanded neuropsychological examination with a qualitative and quantitative estimation of the received results. 56 % of the examined patients had the moderate cognitive disturbance syndrome. Neurodinamical-disregulation and primary-dismnestical types have been revealed. Taking into account, that opportunities of treatment and rehabilitation of patients with dementia noware rather limited, the study of predementical forms of cognitive disturbances when therapeutic actions are considered to be the most effective and of great importance.

2008_01_088_092.pdf212.12 KB