Saratov JOURNAL of Medical and Scientific Research

fosinopril

THE DYNAMICS OF 0,1 HZ-COMPONENT OF HEART RATE VARIABILITY AT PATIENTS WITH ARTERIAL HYPERTENSION AT TREATMENT BY FOSINOPRIL AND ATENOLOL

Year: 2008, volume 4 Issue: №1 Pages: 84-87
Heading: Internal Diseases Article type: Original article
Authors: O.V. Shevchenko, A.R. Kiselev, V.I. Gridnev, O.M. Posnenkova, A.N. Strunina, A.A. Svistunov
Organization: Saratov Institute of Cardiology, Russia, Saratov State Medical University
Summary:

Aim: to study dynamics of the 0,1Hz-componentofthe heart rate variability(HRV) spectrum in patients with arterial hypertension taking fosinopril and atenolol. 49 patients with hypertension were enrolled (age - 46+/-7 years). Fosinopril and atenolol were administered consequently. The power of 0,1 Hz-component of the HRV spectrum was assessed during a passive orthostatic test. Results: In patients taking fosinopril and atenolol comparable decrease of blood pressure was observed. Atenolol caused reliable decrease of a heart rate during orthostatic test. The power dynamics of 0,1Hz-componentwas comparable in patients taking fosinopril and atenolol. Conclusion: fosinopril and atenolol influenced similar on 0,1-Hz mechanisms of vegetative heart control system.

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