Saratov JOURNAL of Medical and Scientific Research

Siberian State Medical University

Evaluation of expenses for treatment of patients with different forms of psoriasis in the conditions of round-the-clock hospital

Year: 2017, volume 13 Issue: №3 Pages: 595-599
Heading: Dermatovenerology Article type: Original article
Authors: Nelyubova O.I., Sazanova G.Yu., Utz S/R.
Organization: Siberian State Medical University
Summary:

 Objective: to evaluate the structure and volume of expenditures on treatment of patients with different clinical forms of psoriasis using the method of analysis of "cost of illness". Material and Methods. The study was conducted on the basis of the Clinic for Skin and Venereal Diseases Medical University of the Saratov State Medical University n.a. V. I. Razumovsky. To determine the costs of treating patients with different clinical forms of psoriasis, 702 medical records of a stationary patient have been analyzed. To assess and analyze the costs of treating patients with psoriasis, one of the methods of clinical and economic analysis was used-the "cost of illness". In the analysis of costs, the costs of inpatient treatment were included, which included direct medical costs, including the payment of medical personnel, the costs of diagnostic, medical manipulation, medicines, the use of medical equipment, inventory, etc.; indirect costs, including the costs of ensuring the activities of the medical institution. The comparative characteristic of the evaluation of the cost of treatment of patients with different forms of psoriasis in accordance with the program of state guarantees and the actual costs of the clinic. Results. It was revealed that the actual cost of the treatment for the completed case of patients with severe forms of psoriasis is 3 times higher than the cost of the treatment under the state guarantees program. The study of the structure of expenditures showed that the main costs are for the purchase of medicines and supplies in severe forms of psoriasis. Conclusion. The difference between the cost of treatment for patients with different forms of psoriasis according to the territorial program of state guarantees of the Saratov region and the actual costs is explained, because the state guarantees program does not take into account comorbid pathology and concomitant diseases, patient's age, which requires additional diagnostic and treatment methods. Analysis of the structure of actual expenditures showed that the maximum share of costs is accounted for by medicines and supplies in severe forms of psoriasis.

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Morphological changes in urinary tract wall after direct electropulse effect: in vitro study

Year: 2011, volume 7 Issue: №4 Pages: 937-941
Heading: Urology Article type: Original article
Authors: Gudkov А.V., Boshchenko V.S., Nedosekov V.V.
Organization: Siberian State Medical University
Summary:

The research goal is to study morphological changes after direct electropulse effect (DEPE) on the wall of urinary tract. Materials and methods: Materials of renal pelvis (25 fragments, n), ureter (n=33) and urinary bladder (n=20) from open surgeries were used. During the surgical intervention a few small fragments were resected to study the organ, immersed on a Petri-dish with solution of 0.9% NaCI. Mucosa was subjected to 1-20 single nanosecond electric impulses of intensity 0.8-1.0 J using probe of electropulse lithotriptor «Urolith-105M». The fragments were fixed in formalin, and then tissue sections were made. Results: Wall of renal pelvis was the most resistant to DEPE. Epithelial desquama-tion, basal disorganization, capillary dilatation and edema were observed within submucosal layer on application up to 10 impulses of intensity 1.0 J in the same point of mucosa. Walls of ureter and urinary bladder were less resistant to the DEPE, where just 5 impulses of intensity 1.0 J caused similar disorders, and 10 impulses of intensity 1.0 J caused damage to the entire thickness of the muscular layer up to adventitia. Conclusion: DEPE of urinary tract mucosa with a number of electric impulses from 1 to 20 with intensity of 0.8 to 1.0 J is a safe method. It causes morphological disorders within the muscular layer but it does not lead to wall perforation

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