Saratov JOURNAL of Medical and Scientific Research

Obninsk Institute of Atomic Energy, Department of Medicine

Integrated assessment of inflammatory process accompanying community-acquired pneumonia by means of radiometry

Year: 2011, volume 7 Issue: №4 Pages: 817-822
Heading: Internal Diseases Article type: Original article
Authors: Arzhnikov V.V., Lifshits V.В., Parfenyuk V.K., Terekhov I.V., Solodukhin K.A., Kondratjev A.S.
Organization: Saratov State Medical University, Saratov State Cardiosurgical Centre, Saratov Hospital MIA, Obninsk Institute of Atomic Energy, Department of Medicine
Summary:

The purpose of the article is to analyze possibility of active SHF radiometry use for inflammation monitoring in lower departments of lungs. Materials and methods: Analysis of humoral immunity (cytokine, complement and immunoglobu-lin status), angiogenesis, and modifications of extracellular matrix has been made by immune-enzyme method. Serum concentration of IL-1(3, IL-1Ra, TGF-(31, C3 and C5a components of complement system and lg M, lg G, VEGF-A, ММП-13 and TIMMP-2 has been estimated in the research. Intensity of radiation of lungs has been studied. Results: Synchronism of radiation dynamics with molecular markers has been determined. The period of changes of specified mediators is about 2 days. Critical time points of pathological process (3, 6, 8, 11 and 16 days) have been found out. Conclusions: It has been proved that SHF radiation of lungs may be applied in treatment of pneumonia for pathology monitoring

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