Saratov JOURNAL of Medical and Scientific Research

Obninsk Institute of Atomic Energy, Department of Medicine

Integrated assessment of inflammatory process accompanying community-acquired pneumonia by means of radiometry

Year: 2011, volume 7 Issue: №4 Pages: 817-822
Heading: Internal Diseases Article type: Original article
Authors: Arzhnikov V.V., Lifshits V.В., Parfenyuk V.K., Terekhov I.V., Solodukhin K.A., Kondratjev A.S.
Organization: Saratov State Medical University, Saratov State Cardiosurgical Centre, Saratov Hospital MIA, Obninsk Institute of Atomic Energy, Department of Medicine

The purpose of the article is to analyze possibility of active SHF radiometry use for inflammation monitoring in lower departments of lungs. Materials and methods: Analysis of humoral immunity (cytokine, complement and immunoglobu-lin status), angiogenesis, and modifications of extracellular matrix has been made by immune-enzyme method. Serum concentration of IL-1(3, IL-1Ra, TGF-(31, C3 and C5a components of complement system and lg M, lg G, VEGF-A, ММП-13 and TIMMP-2 has been estimated in the research. Intensity of radiation of lungs has been studied. Results: Synchronism of radiation dynamics with molecular markers has been determined. The period of changes of specified mediators is about 2 days. Critical time points of pathological process (3, 6, 8, 11 and 16 days) have been found out. Conclusions: It has been proved that SHF radiation of lungs may be applied in treatment of pneumonia for pathology monitoring

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