Saratov JOURNAL of Medical and Scientific Research

Tsipyaschuk A.F.

Saratov State Medical University n.a. V.I. Razumovsky the Clinic of Eye Diseases, Chief Physician, Candidate of Medical Science

The features of general anesthesia by sevofluran in pediatric vitreoretinal surgery with different diseases and ophthalmosurgeral pathologies

Year: 2017, volume 13 Issue: №2 Pages: 426-428
Heading: Ophtalmology Article type: Original article
Authors: Pronin S.N., Yeliseyev N.Yu., Tsypyaschuk A.F.
Organization: Saratov State Medical University
Summary:

Objective: clinical studies of inhalation anesthesia with sevoflurane as the main anesthetic for various diseases in children with vitreoretinal operations. Material and Methods. There was considered the age groups of children from 3 to 16 years old. Among 76 children: 18 with non-prosperrous psycho-emotional statuses, 2 with ICP, 2 with bronchial asthma, 3 with atopic dermatitis, 5 with small anomalies of heart development, 46 were somatically healthy. All of children had different ophthalmosuregery pathology. Results. The performing of general anesthesia by sevoflurane at vitreoretinal surgeries of children with the different diseases and ophthalmological pathologies displayed appropriateness and safety during the surgeries. Conclusion. The appliance of sevoflurane is the reasonable and optimal scheme in modern ophtalmosurgery and anesthesiology.

AttachmentSize
2017_02-1_426-428.pdf235.12 KB

Experience of antiangiogenic and corticosteroid therapy of a diabetic macular edema

Year: 2017, volume 13 Issue: №2 Pages: 383-388
Heading: Ophtalmology Article type: Original article
Authors: Kamenskikh T.G., Batishcheva Yu.S., Kolbenev I.O., Tsipyashchyk A.F., Andreychenko O.A., Gileva E.M., Vasil'yeva T.V., Zakharova N.B.
Organization: Saratov State Medical University
Summary:

Diabetic macular edema (DME) is a leading cause of blindness in patients with diabetes. The purpose of the research is to evaluate the effectiveness of treatment of patients with DMOs resistant to the administration of ranibi-zumab, using the intrauritreal implant "Ozurdex". Material and Methods. 66 patients (98 eyes) are examined. All of the patients were divided, into three groups, depending on a stage of a diabetic retinopathy. The patients underwent a complex of examinations: along with traditional methods, optical coherence tomography, fluorescence angiography of the fundus, multifocal electroretinography, determination of the content of VEGF-Aand cytokines in serum were used. Results. According to ОСТ of a retina and a visometry there are differences in efficiency of treatment depending on a condition balance of cytokine. Conclusion. The use of the intrauretic implant "Ozurdex" was more effective in patients with DMO in the stage of p re-pro I iterative diabetic retinopathy and in patients resistant to anti-VEGF therapy.

AttachmentSize
2017_02-1_383-388.pdf2.1 MB

Primary surgical rehabilitation of children with posttraumatic endophthalmitis

Year: 2017, volume 13 Issue: №2 Pages: 369-372
Heading: Ophtalmology Article type: Original article
Authors: Yeremenko K.Yu., Alexandrova А.А., Tsypyashchuk A.F.
Organization: Saratov State Medical University
Summary:

Purpose: to analyze the results of microinvasive surgical treatment of children with post-traumatic endophthalmitis. Patients and Methods. Under our observation there were 5 children aged 9-13 years with penetrating wounds of the cornea. All children referred to the clinic with clinical manifestations of endophthalmitis. Visual acuity was reduced from 0,01 up to light perception with the correct projection. Results. Lensvitrectomy allowed to visually detect foreign bodies in vitreous and to remove them through the corneal access. Finished the operation by the intraocular introduction of antibiotics and corticosteroids. Criteria of efficiency of treatment: relief ofthe infectious process, the transparency of optical media, lack of subatrophy ofthe eyeball during the observation period of 3-5 months. Conclusion. Timely primary surgical rehabilitation of children with post-traumatic endophthalmitis appropriate, despite the severity of the injury.

AttachmentSize
2017_02-1_369-372.pdf344.03 KB

Cutting edge eye care at the Clinic of Eye Diseases of the Saratov State Medical University

Year: 2017, volume 13 Issue: №2 Pages: 329-334
Heading: Ophtalmology Article type: Original article
Authors: Tsipyashchuk A.F., Kamenskikh T.G., Reshnikova L.B., Polozova N.A.
Organization: Saratov State Medical University
Summary:

The purpose of study is to analyze the results of providing patients with the high-tech medical care at the Clinic of Eye Diseases of the SSMU. Material and methods. Analysis of laws and regulations of the Ministry of Health of the Russian Federation, statistical data, accounting documents of the Clinic of Eye Diseases of the SSMU and a number of other medical institutions that provide patients with the high-tech medical care. A retrospective analysis of original medical records, outpatient medical records, medical charts was carried out. The methods of research that are used in this work include socio-hygienic, retrospective, system analysis, statistical. Results. The implementation of the National Project "Health" by the Clinic of eye diseases of the SSMU is made available through the providing residents of the Saratov region and other 29 regions of the Russian Federation with the high-tech ophthalmic care for. According to the statistical data 3,284 patients were provided with the high-tech medical care in 2014, 2015, 2016. Refractive, vitreoretinal, reconstructive-plastic and optico-reconstructive surgeries, optical through keratoplasty, cross-linking, glaucoma surgery are carried out at the Clinic. The largest number of patients provided with high-tech medical care in 2014-2016 had vitreoretinal surgeries. Conclusion. There is a significant increase in the functional results of patients' treatment, increasing accessibility and quality of high technologies in ophthalmology. Successful providing patients with the high-tech medical care was facilitated by the creation of a special commission of identifying the patients required the high-tech medical care, concerted efforts of the physicians and nurses, state-of-the-art diagnostic and therapeutic equipment.

AttachmentSize
2017_02-1_329-334.pdf764.48 KB

Significance Of Immunohistochemical Markers In Diagnostics Of Urinary Bladder Cancer

Year: 2009, volume 5 Issue: №4 Pages: 608-611
Heading: Urology Article type: Original article
Authors: G.N. Maslyakova, A.N. Ponukalin, E.N. Tsmokalyuk, A.B. Bucharskaya, A.V. Medvedeva
Organization: Saratov State Medical University
Summary:

On the basis of surgical and biopsy material 106 patients with diseases of urinary bladder have been under study. They received treatment at Scientific Research Institute of Fundamental and Clinical Uronephrology of Saratov State Medical University. 13 immunohistochemical markers have been evaluated: markers of proliferative activity - Ki-67, PCNA, p63, suppressor of tumor growth - p53, markers of apoptosis - Bcl-2, Bax, receptor of epidermal growth factors - EGFR, cytokeratin profile - (CK7, CK8, CK10/13, CK 17, CK18, CK19), as well as their diagnostic significance for identifying the urinary bladder cancer

AttachmentSize
200904_608_611.pdf350.04 KB

Clinical And Morphological Androgenic Status Characteristics At Children Suffering From Hypospadias And Its Influence On Results Of Surgical Correction

Year: 2009, volume 5 Issue: №3 Pages: 433-437
Heading: Urology Article type: Original article
Authors: D.A. Zharkov, N.Ju. Raigorodskaya, F.K. Napolnikov, E.N. Tsmokalyuk
Organization: Saratov Clinical Hospital №3, Saratov State Medical University
Summary:

The goal of this article is to estimate the androgenic status and analyze its influence on the surgical treatment of hypospadias. From 2000 till 2008 there were 209 children under treatment, whose age varied from 8 months till 15 years old (average age — 4,5+ 1,5). 49 patients were subjected to clinical, humoral and morphological study. Preoperational preparation was carried out by testosterone medications. The comparison group consisted of 10 boys with cicatricial phimosis.
The patients with the medium and back forms of hypospadias suffered from the androgenic deficit characterized by proximal level of meatus ectopia, diminution of penis length and prostate volume, decrease of blood vessels in deep layers of penis skin. The testosterone pre-operational medication of patients makes possible to improve the results of surgical correction due to blood supply of plastic material. On the basis of recieved data logistically regressive model has been worked out and the prognosis of results has been estimated

AttachmentSize
200903_433_437.pdf1.4 MB

INDIVIDUAL AND TYPOLOGICAL ORBIT VARIABILITY OF ADULTS WITH DIFFERENT SHAPE OF FACIAL CRANIUM

Year: 2008, volume 4 Issue: №1 Pages: 43-47
Heading: Macro- and Micromorphology Article type: Original article
Authors: A.F. Tsipyaschuk, V.N. Nikolenko, T.M. Zagorovskaya, O.A. Fomicheva
Organization: Saratov State Medical University
Summary:

Individual and anatomical peculiarities of dimensions and shape of the orbitofadult peoples (n=102) were studied with different shape of the facial cranium. More expressed dimensions of the superior and lateral walls of the orbit in leptoprozopic and eurioprozopic shape of the cranium. Depth of the orbitdependon of shape of the facial cranium.

Keywords: -
AttachmentSize
2008_01_043_047.pdf206.57 KB