Saratov JOURNAL of Medical and Scientific Research

Baityakov V. V.

Saransk, Mordovia N.P. Ogarev State University, associate professor, course of the skin and venereal diseases, candidate of medical sciences

The clinical efficacy of extracorporeal and intravascular hemocorrection methods in psoriasis

Year: 2012, volume 8 Issue: №1 Pages: 081-084
Heading: Skin Diseases Article type: Original article
Authors: Baityakov V.V., Kurkina V.A.
Organization: Mordovian State University
Summary:

Purpose. The study of the influence of extracorporeal and intravascular hemocorrection methods (plasmapheresis, ultraviolet blood radiation, ozonetherapy and its combination) on skin process and life quality in patients with extensive psoriasis. Methods. 253 patients with extensive psoriasis from the age of 18 to 72 have been investigated. PASI (Psoriasis Area and Severity Index) and dermatological index of life quality (DILQ) have been used for treatment assessment. Results. The inclusion of efferent quantum and ozone therapy methods in the complex treatment of psoriasis has promoted to the more rapid and complete positive dynamics of skin process and the improvement of life quality. The use of plasmapheresis and its variations with photomodification or the ozone treatment of returning erythrocyte suspension has been the most effective. Plasmapheresis and its modifications are appropriateto be used in the complex treatment of the patients with severe forms of psoriasis. Conclusion: Further study of efferent quantum and ozone therapy methods and their wider use in psoriasis therapy and other chronic dermatosis seem to be promising.

AttachmentSize
201201_081-084_.pdf275.62 KB

The peculiarities of the metabolism processes in patients with the exacerbation of extensive psoriasis

Year: 2011, volume 7 Issue: №3 Pages: 633-636
Heading: Skin Diseases Article type: Original article
Authors: Baityakov V. V.
Organization: Mordovian State University
Summary:

Purpose. The study of some indices of the metabolism in patients with the exacerbation of extensive psoriasis, the investigation of the revealed disorder dependence on the clinical peculiarities of the disease and anamnesis data. Methods. 253 patients with extensive psoriasis from the age of 18 to 72 have been investigated.Some indices of lipid and protein metabolism, medium molecular peptide content, lipid peroxidation and antioxidant protection processes in blood plasma have been studied. Results. Dysproteinemia, the increase of С — reactive protein level, seromucoid, medium molecular peptides, common lipids, triglycerides, the reduction of the level of lipid proteins of high density, the intensification of lipid peroxidation processes and the reduction of antioxidant activity have been marked in blood plasma in patients with the exacerbation of extensive psoriasis. The dependence of some indices of metabolism on the clinical picture and the severity of skin process, age, family history has been revealed. Conclusion. Metabolism disorders in patients with psoriasis are of systemic character. It seems appropriate to carry out a deep study of metabolism indices in patients with psoriasis with the following correction of the revealed disorders

AttachmentSize
201103_633-636.pdf323.22 KB