Saratov JOURNAL of Medical and Scientific Research

Myasnikov I. L.

Russian State Medical University n.a. N. I. Pirogov, Department of Normal Physiology, Associate Professor, Candidate of Medical Science

Study of nerve fibers nature reinforcing duodenal contractions by electrical stimulation of sympathetic nerve

Year: 2011, volume 7 Issue: №3 Pages: 580-583
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Sveshnikov D.S., Kirichuk V.F., Smirnov V.M., Myasnikov I. L, Kuchuk A.M., Trofimova J.E., Trubetskaya M.A.
Organization: Saratov State Medical University, Russian State Medical University
Summary:

The subject of the article is to investigate the mechanism of increased reactions by electrical stimulation of the sympathetic nerve. Materials and methods: Experiments on dogs have shown that stimulant reactions during blockade of a-adrenergic by phentolamine and (3-adrenergic receptors with propranolol were completely eliminated by lizer-gol —the blocker of 5-HT12-receptors. Results: Infusion of lizergol did not influence on duodenal motor activity and the function of the vagus nerve. Conclusion: Effector neuron is found out to be serotonergic and its action is provided by 5-HT1 2 receptors

AttachmentSize
201103_580-583.pdf517.92 KB

Study of sympathetic trunk fibers nature for cause determination of increase of stomach contractions

Year: 2010, volume 6 Issue: №2 Pages: 392-395
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Smirnov V.М., Sveshnikov D.S., Kirich и к V.F., Myasnikov I. L, Kuchuk A.V.
Organization: Saratov State Medical University, Russian State Medical University
Summary:

The investigation has revealed that stimulation of sympathetic nerve in the thoracic cavity in dogs provides no inhibition but increase in stomach contractions in most cases. This effect is raised with the blockage of a-and (3-adrenergic receptors and it is removed by blockage of 5-HT12-receptors. It has been stated that there are serotonergic fibers that increase stomach contractility

AttachmentSize
201102_392-395.pdf357.21 KB