Rodionova T.I.

Probability of relapse development of diffuse toxic goiter during the nearest two years after treatment is determined by its results and stressogenic capacity level, which is defined by Holmes and Rage method. As long as satisfactory treatment results and level of stressogenic capacity are above 300 points, the risk of diffuse toxic goiter relapse run to 68,5%

The article examines the factors influencing availability of insulinotherapy, modern insulin types, methods of insulin administration, and insulin pump as one of its number. The authors explicate some challenges connected with availability of insulin therapy for patients with type 1 diabetes mellitus belonging to various social groups

Significance of biological feedback (BFB) therapy in complex treatment of patients with thyrotoxic myocardiodystrophy was analyzed. Evaluation of bioregulation procedures was conducted in 36 patients with diffusive toxic goiter (DTG) and signs of thyrotoxic myocardiodystrophy on the background of drug therapy. Control group consisted of 24 patients with DTG, which took only drug therapy. It was revealed, that combination of drug therapy of DTG with BFB procedures provided significant influence on state of vegetative nervous system, and it also led to quick decrease of clinical symptoms of thyrotoxic myocardiodystrophy, in contrast to isolated drug therapy

This review presents the modern data concerning influence ofsubclinicalhypothyroidism on morphology and functional state of myocardium and arterial vessels, traditional and "new" cardiovascular risk factors. The riskof clinically significant complications (cardiovascular diseases, disorders ofhemostasis and changes in lipidexchange) connected with subclinical hypothyroidism is under research. The data on the effects of subclinical hypothyroidism substitutional therapy are highlighted in the work

The authors present contemporary data of mechanisms of thyroid hormones action on myocardial metabolism. Special attention was paid to non-genomic effects of thyroid hormones; the authors also discuss alterations in metabolic pathways and structural changes of myocardium which are developing in hypothyroid condition.