Saratov JOURNAL of Medical and Scientific Research

index of disease course

New approach to surgery in obliterating atherosclerosis of lower limb arteries

Year: 2010, volume 6 Issue: №4 Pages: 850-856
Heading: Surgery Article type: Original article
Authors: Kazantsev A.M., Korymasov E.A.
Organization: Samara State Medical University
Summary:

Complex examination of 296 patients with obliterating atherosclerosis of lower extremities was carried out. Prog-nostically significant clinical, hemodynamic, hemostatic, immunological characteristics, markers of endothelial dysfunction and changes in lipid profile in patients were studied. Pathogenetic system of disease prognosis was worked out as a result of multifactor analysis where the index of course of disease was accounted. When the index was lower than + 13, obliterating atherosclerosis was not considered as progressive. Progressive atherosclerosis was determined with the index over the point +13

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