Saratov JOURNAL of Medical and Scientific Research

Narcology

Paracentetic Access to Sensory Root of Tri-geminus: Anatomic and Topographic Features

Year: 2012, volume 8 Issue: №3 Pages: 785-790
Heading: Narcology Article type: Review
Authors: Chekhonatsky A.A., Skulovitch S.Z., Ushakov D.A., Lotsmanov Yu.F.
Organization: Saratov State Medical University
Summary:

Anatomic and topographic features of middle cranial fossa which should be taken into account during paracentetic access to sensory root of trigeminus are examined in the article. It is substantiated that treatment of trigeminus neuralgia needs bounded influence on sensory root of trigeminus. The authors based the idea of paracentetic access to sensory root of trigeminus through for. ovale. Such possible complexities and specific features as: probable confluence of for. ovale with other holes, calcification of ligamentous apparatus, and presence of holes due to this process should be considered during surgery.

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General methods of identification of narcotic substances in cadaveric urine and biochemical indices in blood at positive identification of drug substances

Year: 2011, volume 7 Issue: №3 Pages: 642-646
Heading: Narcology Article type: Original article
Authors: Bychkov E.N., Serkova S.A., Arsentieva L.A., Frantsuzova T.S., Bluvshtein G.A., Borodulin V.B.
Organization: Saratov State Medical University, Saratov Bureau of Forensic Medical Examination
Summary:

The goal of the present paper was to find effective biochemical markers of chronic narcotization. Materials and methods. The results of biochemical research of biological liquids in human organism and chromatographic methods of drug substances identification in cadaveric urine were analyzed. Research of 197 samples of different biologic liquids of 10 persons was carried out. Control was fulfilled on the basis of 135 samples of biological liquids took of 12 persons. Methods of identification of drug substances are presented, chromatographic and spectral characteristics of drug substances are described. Interrelations of biochemical indices at positive study of drug substances identification were conducted. The increased urea metabolic concentration in cadaveric blood of drug addicts was revealed in comparison with control specimens. Results. (Numeral results are given in Table 3). Correct correlation of biochemical markers was not established. Conclusion. The present results suppose continued study of informative reliable biochemical markers of chronic drug intoxication

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Pathogenetic aspects of alcoholic encephalopathy treatment

Year: 2010, volume 6 Issue: №4 Pages: 796-799
Heading: Narcology Article type: Review
Authors: Shchetinin S.G., Barylnik Yu.B., Lim V.G.
Organization: Saratov State Medical University
Summary:

Alcohol is considered to be the most common exogenous toxins, causing encephalopathy. The defeat of almost all parts of the nervous system should be assigned to the special features of ethanol. Neurophysiological mechanisms of development of substance dependence are based in the stem and limbic structures of the brain that are involved in ensuring the regulation of emotional state, mood, motivation sphere, psychophysical tone of human behavior in general and its adaptation to the environment. Stress or disruption of the normal functioning of these structures can lead to the formation of abstinence syndrome, affective disorders in remission and craving for alcohol. Dopaminergic and opioid (endorphin) system play an important role in the genesis of various mental and motor disorders. In some way alcohol dependence can be regarded as an endorfinodefitsitnoe disease with a pathogenetic point of view. Activating of opioidereal system by trans-cranial electrical stimulation promotes the restoration of disturbed emotional, cognitive and autonomic functions, reduces craving for alcohol and in that way increases the effectiveness of rehabilitation treatment

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