Saratov JOURNAL of Medical and Scientific Research

fluoroquinolones

Substantiation of the differentiated approach to the therapy by antibiotics at an aggravation of the extented chronic periodontitis

Year: 2011, volume 7 Issue: №1 Pages: 287-288
Heading: Stomatology Article type: Short message
Authors: Guseva O.U., Bulkina N.V., Osipova J.L., Kropotina A.Yu., Albitskaya J.N.
Organization: Saratov State Medical University
Summary:

Investigated biochemical changes in an oral liquid of patients with the extented chronic periodontitis chronic in aggravation stage, specific features of change of activity of enzymes of a mouth at presence fluoroquinolones , in the presence of the expressed inflammatory process in periodontium are revealed. The studied biochemical mechanisms of action of preparations can serve as criterion of a choice of the optimal preparation that will allow to improve essentially results of treatment of the given category of patients

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EXPERIENCE OF RESPIRATORY FLUOROHINOLONUM LAEVOFLOXACINE APPLICATION («FLORACID®») IN PATIENTS WITH NON-SEVERE COMMUNITY-ACQUIRED PNEUMONIA

Year: 2007, volume 3 Issue: №3 Pages: 65-67
Heading: Internal Diseases Article type: Original article
Authors: A.P. Rebrov, E.Yu. Ponomarеva, I.A. Amirova
Organization: Saratov State Medical University
Summary:

The dynamics of clinical and laboratory parameters in patients with community-acquired pneumonia were studied during the treatment with respiratory fluorohinolonum laevofloxacin «Floracid®». The high efficiency and safety of «Floracid®» were revealed during the research.

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CLINICAL USE OF MODERN FLUOROQUINOLONES IN DENTAL IMPLANTATION AND MAXILLARY SINUS LIFTING

Year: 2009, volume 5 Issue: №1 Pages: 92-95
Heading: Stomatology Article type: Original article
Authors: A.M. Panin, V.N. Tsarev, V.I. Chuvilkin, S.A. Novikov
Organization: Moscow State Stomatological University
Summary:

New fluoroquinolones like levofloxacine, with broad-spectrum of effect which is also active against anaerobic bacteria, is a prospective drug for the prevention of the inflammatory complications in implant dentistry and maxillary sinus augmentation. 34 patients have been selected for this study, including 16 women and 18 men aged 18-65. All the patients have been classified into the main and control groups. Patiens of the first group have been prescribed 500 mg of levofloxacine before and after the operation two times a day for 10 days. Patients of the control group have been treated with amocxicilline. In the control group, which has used amoxicilline, Streptococcus sanguis, Streptococcus salivarius and anaerobic bacteria have been identified. The amount of Prevotella intermedia is insignificant. The same picture has been found with Fusobacterium spp. The rate of Actinomyces spp. was insignificant over the whole period of study. Patients of the experimental group had a slightly different distribution of bacteria. On the 10th day after the operation in the main patient group no periodontal pathogenesis, which may cause inflammatory complications have been identified. During the early post-operative period no significant differences have been observed among the patients of both groups.

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