Saratov JOURNAL of Medical and Scientific Research

Kolokolov O.V.

Saratov State Medical University n.a. V.I. Razumovskyofthe Ministry of Health of Russia, Head of Department of Neurology n. a. K.N. Tretiakov, Faculty of Continuing Medical Education, Associate Professor, Doctor of Medical Science

Features of epi-demiological situation on HIV-infection in Saratov region

Year: 2017, volume 13 Issue: №3 Pages: 489-494
Heading: Infectious Diseases Article type: Original article
Authors: Sotskova V.A., Shuldyakov А.А., Kolokolov O.V., Abramyan T.L., Potemina L.P., Tsareva T.D., Perminova Т.А.
Organization: Saratov Regional Centre for Disease Prevention and Control of AIDS and Infectious Diseases, Saratov State Medical University
Summary:

Objective: to perform analysis of HIV-infection epidemic in the Saratov region in the period from 1996 to 2015. Material and Methods. Epidemiological and static methods have been used, retrospective epidemiological analysis of HIV-infection progression on the territory of the region has been performed. Results. Excess incidence and prevalence of HIV-infection in the region has been noticed. The main virus routes are injections of narcotic drugs and sexual transmission. From 2009 the persons over 30 years old have been involved in the epidemical process to a greater extent. The increase in the number of women of fertile age among incident cases of HIV-infection has been registered. Increasing incidence rate of HIV-infection among rural people occurred. Conclusion. In the Saratov region, as well as in the Russian Federation, high burden of HIV-infection continues to persist, that imposes more detailed study of the problem.

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Paraneoplastic neurological syndrome: focus on the involvement of the peripheral nervous system

Year: 2017, volume 13 Issue: №1 Pages: 174-180
Heading: Neurology Article type: Review
Authors: Sitkali I.V., Kolokolov O.V.
Organization: Saratov State Medical University
Summary:

The information about epidemiology, pathogenesis and clinical heterogeneity of paraneoplastic neurological syndrome is summarized and based on Russian and foreign literature. The main attention is devoted to the affection of peripheral nervous systems in patients with oncological diseases. We report the information about anti-neuronal antibodies associated with paraneoplastic syndrome. The diagnostic criteria of paraneoplastic neurological syndromes are presented.

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Konstantin Nikolaevitch Tretiakoff: some of the biography pages (the 125th anniversary of the birth)

Year: 2017, volume 13 Issue: №1 Pages: 123-127
Heading: Neurology Article type: Short message
Authors: Kolokolov O.V., Razdorskaya V.V., Yudina G.K.
Organization: Saratov State Medical University
Summary:

Konstantin Tretiakov is one of the founders of Neurological science schools in Sao Paulo (Brazil) and in Saratov. Carrying out the analysis of the materials of the State archive of Saratov, the Russian State Library, the Russian National Library, the library of Saratov Medical University, Internet resources. The information about the K.N. Tretiakov's life, career and scientific work Tretiakov is presented.

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Hereditary neuropathies: systematization and diagnostics (clinical case of hereditary motor and sensor neuropathy of the IA type)

Year: 2016, volume 12 Issue: №3 Pages: 370-375
Heading: Neurology Article type: Case report
Authors: Kolokolova A.M., Sitkali I.V., Kolokolov O.V.
Organization: Saratov State Medical University
Summary:

Aim: to study the value of routine methods (clinical symptoms, electrophysiological findings and results of DNA analysis) in diagnostics of hereditary motor sensory neuropathy type IA in outpatient clinics. Material and Methods. The review of foreign literature is represented. The phenotypic polymorphism, genetic heterogeneity and the difficulties of diagnostics are identified. A family with hereditary motor sensory neuropathy of lAtype is presented, which was diagnosed on the base of available methods in outpatient practice (clinical symptoms, genealogical method, electro-physiological findings and DNA analysis results). Results. Routine algorithm (consistent valuation of clinical symptoms, neurophysiologic findings and the results of DNA analysis) helped to verify the diagnosis of hereditary motor sensory neuropathy of lAtype in outpatient practice after more than 20 years of the onset of the disease. Conclusion. The neurologists of outpatient clinics and other specialists must be informed about the availability of diagnostics of hereditary diseases of nervous system.

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Nervous system diseases comorbid to psoriasis

Year: 2016, volume 12 Issue: №2 Pages: 300-303
Heading: Neurology Article type: Review
Authors: Fisun A.V., Kolokolov O.V., Bakulev A.L., Makarov N.S., Kravchenya S.S., Schabogina A.A., Popova O.V.
Organization: Saratov State Medical University
Summary:

The information about the cormorbid pathology in patients with skin and nervous systems diseases is summarized on the base of Russian and foreign scientific literature. The main attention is devoted to the combination of nervous system pathology with psoriasis and psoriatic arthritis. The high risk of cerebrovascular diseases development is pointed in psoriasis. Material concerning neuropathy caused by the cytostatics usage is represented in patients with psoriasis.

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Rare forms neurological disorders in an HIV-infected patient

Year: 2016, volume 12 Issue: №2 Pages: 296-299
Heading: Neurology Article type: Case report
Authors: Sotskova V.A., Kolokolov O.V., Shuldyakov А.А., Makarov N.S.
Organization: Saratov State Medical University
Summary:

The study aims paying the attention of specialists in rare cases of pathology of the nervous system in HIV-infected patients. The clinical case of brain abscess in a 32 year-old HIV-positive patient. Against the background of the surgical and antiretroviral treatment of brain abscess in HIV-positive patients it managed to achieve a virologic response and regression of neurological symptoms. Presented clinical case can be useful for specialists in determining the tactics of treatment of brain abscess in HIV-infected patients.

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Polyneuropathy: clinical polymorphism and the algorithms of diagnostics

Year: 2016, volume 12 Issue: №2 Pages: 292-296
Heading: Neurology Article type: Review
Authors: Sitkali I.V., Kolokolov O.V., Lukina E.V., Grigorieva E.A., Popova O.V.
Organization: Saratov State Medical University
Summary:

The information about epidemiology and clinical polymorphism of neuropathies is summarized on the base of Russian and foreign literature. The algorithm of clinical observation in patients with polyneuropathy is presented.

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Parkinsonism accompanying the left frontal lobe tumor

Year: 2016, volume 12 Issue: №2 Pages: 285-287
Heading: Neurology Article type: Case report
Authors: Razdorskaya V.V., Kolokolov O.V., Lomakin A.l., Yudina G.K.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University
Summary:

Objective: to draw the attention of experts on rare cause of secondary parkinsonism — a brain tumor. Material and methods. The clinical observation of the patient 52 years with Parkinson's syndrome. Brain MRI. Results. In parallel the patient had classical progressing clinic bilateral parkinsonism in combination with progressive cognitive decline. MRI research revealed the left frontal lobe tumor. Conclusions. Secondary parkinsonism as a result of intracerebral neoplasms are caused mostly by compression of basal ganglia or mesencephalon increasing tumors. Hemiparkinsonism in these cases usually precedes the other focal neurological symptoms.

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Migreine and periictal headache in patients with epilepsy

Year: 2016, volume 12 Issue: №2 Pages: 278-281
Heading: Neurology Article type: Review
Authors: Muzalevskaia D.S., Korotkov A.G., Kolokolov O.V.
Organization: Saratov State Medical University
Summary:

Migraine and epilepsy are diseases characterized by paroxysmal occurring clinical manifestations that have different mechanisms of pathogenesis. In the interictal period in 59% of patients with epilepsy there are different types of primary headache: 18%, migraine without aura, 33% from tension-type headache, and 8% not classified headache. We have analyzed clinical and electrophysiological pattern in patients with migraine and idiopathic generalized epilepsy. A preliminary analysis of the clinical picture of headaches in adult patients suffering from idiopathic generalized epilepsy suggests that migraine occurs more often in patients with idiopathic generalized epilepsy, whereas among patients with focal symptomatic epilepsy is more common patients with secondary headache

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The role of transient ischemic attacks in the occurrence of cognitive impairment

Year: 2016, volume 12 Issue: №2 Pages: 273-277
Heading: Neurology Article type: Review
Authors: Maleina A.U., Kolokolov O.V., Lukina E.V.
Organization: Saratov State Medical University
Summary:

The information about cognitive impairment of patient, suffered from transient ischemic attack (TIA) is summarized on the base of Russian and foreign literature. There were considered primary risk factors and pathogenesis of the occurrence of TIA and cognitive impairment. The algorithm of examination of patients with TIA was presented.

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