Saratov JOURNAL of Medical and Scientific Research

Kolokolov O.V.

Saratov State Medical University n.a. V.I. Razumovskyofthe Ministry of Health of Russia, Head of Department of Neurology n. a. K.N. Tretiakov, Faculty of Continuing Medical Education, Associate Professor, Doctor of Medical Science

Public knowledge of risk factors, signs and treatment of stroke: Analysis of the survey results in 2014 and 2017

Year: 2018, volume 14 Issue: №1 Pages: 177-185
Heading: Neurology Article type: Original article
Authors: Shchanitsyn I.N., Razdorskaya V.V., Kolokolov O.V., Lukina E.V., Loi'ko V.S,
Organization: Center of Medical Inspection, Moscow, Saratov State Medical University
Summary:

Aim. This study was conducted to establish levels of knowledge in the general population, and also to determine the impact of educational sessions on stroke knowledge. Material and Methods. Two groups (2014 and 2017 years) completed a stroke knowledge questionnaire (435 respondents). Results. Overall, most of respondents could list 2 or more risk factors, but only 50% in 2014 could list 3 warning signs. More than 80% would call emergency number in response to stroke, but only 25% had heard of thrombolytic therapy. Overall stroke knowledge scores decreased in 2017 despite the public awareness in the media. Conclusion. Currently the knowledge of stroke risk factors, warning signs, and treatment is poor in Saratov. Our study demonstrates that more educational campaigns should be conducted for improve knowledge of stroke symptoms, and therapy.

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Neuroinfection in patient with HIV: case report

Year: 2018, volume 14 Issue: №1 Pages: 168-173
Heading: Neurology Article type: Case report
Authors: Sotskova V.A., Bachilo Е.М., Shuldyakov А.А., Kolokolov O.V., Barylnik Yu.B., Potemina L.P., Krajnova O.N.
Organization: Saratov Regional Centre for Disease Prevention and Control of AIDS
Summary:

Toxoplasmosis is one of the most common opportunistic infections in HIV-positive patients. The onset of HIV-infection with cerebral toxoplasmosis makes this disease a multidisciplinary problem and requires the participation of doctors of various specialties (infectious disease specialists, neurologists, neurosurgeons, general practitioners, etc.). Early diagnosis and treatment of this disease will reduce the risk of deaths and severe consequences. We carry out an analysis of the clinical case of toxoplasma encephalitis in a HIV-infected patient. We have identified errors in the establishing diagnosis. We have given a detailed account a patient management plan. We also comment on some of the problem early disease detection HIV-infection.

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"Benign" multiple sclerosis: a variant of favorable disease course and the result of effective treatment

Year: 2018, volume 14 Issue: №1 Pages: 153-156
Heading: Neurology Article type: Review
Authors: Makarov N.S., Kolokolov O.V.
Organization: Saratov State Medical University
Summary:

The article provides an overview of data on isolated demyelination syndromes that may precede multiple sclerosis, and on the peculiarities of the so-called "benign" form of multiple sclerosis. Clinical and anamnestic criteria for establishing the fact of a "benign" form of multiple sclerosis are presented, as well as trends in the number of these patients in the general population of patients with multiple sclerosis, including in connection with the improvement of treatment methods for this disease.

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Features of epi-demiological situation on HIV-infection in Saratov region

Year: 2017, volume 13 Issue: №3 Pages: 489-494
Heading: Infectious Diseases Article type: Original article
Authors: Sotskova V.A., Shuldyakov А.А., Kolokolov O.V., Abramyan T.L., Potemina L.P., Tsareva T.D., Perminova Т.А.
Organization: Saratov Regional Centre for Disease Prevention and Control of AIDS, Saratov State Medical University
Summary:

Objective: to perform analysis of HIV-infection epidemic in the Saratov region in the period from 1996 to 2015. Material and Methods. Epidemiological and static methods have been used, retrospective epidemiological analysis of HIV-infection progression on the territory of the region has been performed. Results. Excess incidence and prevalence of HIV-infection in the region has been noticed. The main virus routes are injections of narcotic drugs and sexual transmission. From 2009 the persons over 30 years old have been involved in the epidemical process to a greater extent. The increase in the number of women of fertile age among incident cases of HIV-infection has been registered. Increasing incidence rate of HIV-infection among rural people occurred. Conclusion. In the Saratov region, as well as in the Russian Federation, high burden of HIV-infection continues to persist, that imposes more detailed study of the problem.

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Paraneoplastic neurological syndrome: focus on the involvement of the peripheral nervous system

Year: 2017, volume 13 Issue: №1 Pages: 174-180
Heading: Neurology Article type: Review
Authors: Sitkali I.V., Kolokolov O.V.
Organization: Saratov State Medical University
Summary:

The information about epidemiology, pathogenesis and clinical heterogeneity of paraneoplastic neurological syndrome is summarized and based on Russian and foreign literature. The main attention is devoted to the affection of peripheral nervous systems in patients with oncological diseases. We report the information about anti-neuronal antibodies associated with paraneoplastic syndrome. The diagnostic criteria of paraneoplastic neurological syndromes are presented.

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Konstantin Nikolaevitch Tretiakoff: some of the biography pages (the 125th anniversary of the birth)

Year: 2017, volume 13 Issue: №1 Pages: 123-127
Heading: Neurology Article type: Short message
Authors: Kolokolov O.V., Razdorskaya V.V., Yudina G.K.
Organization: Saratov State Medical University
Summary:

Konstantin Tretiakov is one of the founders of Neurological science schools in Sao Paulo (Brazil) and in Saratov. Carrying out the analysis of the materials of the State archive of Saratov, the Russian State Library, the Russian National Library, the library of Saratov Medical University, Internet resources. The information about the K.N. Tretiakov's life, career and scientific work Tretiakov is presented.

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Hereditary neuropathies: systematization and diagnostics (clinical case of hereditary motor and sensor neuropathy of the IA type)

Year: 2016, volume 12 Issue: №3 Pages: 370-375
Heading: Neurology Article type: Case report
Authors: Kolokolova A.M., Sitkali I.V., Kolokolov O.V.
Organization: Saratov State Medical University
Summary:

Aim: to study the value of routine methods (clinical symptoms, electrophysiological findings and results of DNA analysis) in diagnostics of hereditary motor sensory neuropathy type IA in outpatient clinics. Material and Methods. The review of foreign literature is represented. The phenotypic polymorphism, genetic heterogeneity and the difficulties of diagnostics are identified. A family with hereditary motor sensory neuropathy of lAtype is presented, which was diagnosed on the base of available methods in outpatient practice (clinical symptoms, genealogical method, electro-physiological findings and DNA analysis results). Results. Routine algorithm (consistent valuation of clinical symptoms, neurophysiologic findings and the results of DNA analysis) helped to verify the diagnosis of hereditary motor sensory neuropathy of lAtype in outpatient practice after more than 20 years of the onset of the disease. Conclusion. The neurologists of outpatient clinics and other specialists must be informed about the availability of diagnostics of hereditary diseases of nervous system.

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Nervous system diseases comorbid to psoriasis

Year: 2016, volume 12 Issue: №2 Pages: 300-303
Heading: Neurology Article type: Review
Authors: Fisun A.V., Kolokolov O.V., Bakulev A.L., Makarov N.S., Kravchenya S.S., Schabogina A.A., Popova O.V.
Organization: Saratov State Medical University
Summary:

The information about the cormorbid pathology in patients with skin and nervous systems diseases is summarized on the base of Russian and foreign scientific literature. The main attention is devoted to the combination of nervous system pathology with psoriasis and psoriatic arthritis. The high risk of cerebrovascular diseases development is pointed in psoriasis. Material concerning neuropathy caused by the cytostatics usage is represented in patients with psoriasis.

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Rare forms neurological disorders in an HIV-infected patient

Year: 2016, volume 12 Issue: №2 Pages: 296-299
Heading: Neurology Article type: Case report
Authors: Sotskova V.A., Kolokolov O.V., Shuldyakov А.А., Makarov N.S.
Organization: Saratov State Medical University
Summary:

The study aims paying the attention of specialists in rare cases of pathology of the nervous system in HIV-infected patients. The clinical case of brain abscess in a 32 year-old HIV-positive patient. Against the background of the surgical and antiretroviral treatment of brain abscess in HIV-positive patients it managed to achieve a virologic response and regression of neurological symptoms. Presented clinical case can be useful for specialists in determining the tactics of treatment of brain abscess in HIV-infected patients.

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Polyneuropathy: clinical polymorphism and the algorithms of diagnostics

Year: 2016, volume 12 Issue: №2 Pages: 292-296
Heading: Neurology Article type: Review
Authors: Sitkali I.V., Kolokolov O.V., Lukina E.V., Grigorieva E.A., Popova O.V.
Organization: Saratov State Medical University
Summary:

The information about epidemiology and clinical polymorphism of neuropathies is summarized on the base of Russian and foreign literature. The algorithm of clinical observation in patients with polyneuropathy is presented.

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