Saratov JOURNAL of Medical and Scientific Research

Kudaeva L.A.

Railway Clinical Hospital ad st. Voronezh-1, Cardiologist

The role of infectious stimulus in the initiation and immune inflammation in psoriasis

Year: 2014, volume 10 Issue: №3 Pages: 530-537
Heading: Skin Diseases Article type: Review
Authors: Slesarenko N.A., Utz S.R., Kulaev K.A., Resnikova M.A., Panina L.V., Popova O.V.
Organization: Saratov State Medical University
Summary:

Psoriasis is a common skin disease in which the development of the decisive role played by genetic and environmental factors. Many of the candidate genes linked with psoriasis, are directly related to acquired or congenital defects of the immune system, epithelial barrier permeability of the intestinal wall, and the keratinocyte membrain. Formation of an immune response to Th-1 type high expression and activity of antimicrobial peptides like state at their potential infection. This review discusses the possible immune mechanisms are involved in the relationship between infection and disease process in psoriatic skin. We survey the literature and discuss the suitability of infection factors in treatment modality for psoriasis.

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Clinical case Netherton syndrome

Year: 2013, volume 9 Issue: №3 Pages: 605-607
Heading: Dermatovenerology Article type: Case report
Authors: Bakulev A.L, Karakaeva A.M., Kulyaev K.A., Epifanova A.U., Katkova I.O., Slesarenko N.A., Davtyan V.A., Kolpakova N.N.
Organization: Saratov State Medical University
Summary:

This article presents a clinical case of Netherton syndrome in a child is a severe pathology, the presence of which leads to disability. Treatment and management of patients with this dermatosis today is still relevant and not unsettled problem.

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2013-03_1-605-607.pdf1.16 MB

Clinico-diagnostic cases of infiltrative-suppurative microsporia and kerion in parallels

Year: 2013, volume 9 Issue: №3 Pages: 601-604
Heading: Dermatovenerology Article type: Case report
Authors: Kulyaev К.A., Epifanova A.U., Katkova I.О., Karakaeva AM., Slesarenko N.A., Eremina M.G., Davtyan V.A., Kolpakova N.N.
Organization: Saratov State Medical University, clinic skin and venereal diseases
Summary:

This article presents a case of kerion relating to the rarely seen infectious dermatoses. There are the differences in differential diagnostics of infiltrative-suppurative microsporia and kerion.

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2013-03_1-601-604.pdf2.34 MB

Application of infrared A spectrum transmitted through the water filtering (Photo Dyn750) in the treatment of acne

Year: 2013, volume 9 Issue: №3 Pages: 572-574
Heading: Dermatovenerology Article type: Review
Authors: Katkova I.О., Bakylev A.L., Epifanova A.Yu., Kulyaev K.A., Davtyan V.A., Kolpakova N.N.
Organization: clinic skin and venereal diseases, Saratov State Medical University
Summary:

There had been organized the analysis of the current ideas on the etiology, pathogenesis, therapeutic methods of acne treatment. The use of infrared radiation (Photo Dyn750) is a promising technique in the treatment of acne.

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2013-03_1-572-574.pdf222.51 KB

The case of annular type of pustular psoriasis in a child

Year: 2012, volume 8 Issue: №2 Pages: 654-657
Heading: Skin Diseases Article type:
Authors: Slesarenko N.A., Kulaev K.A., Karakaeva A.V., Russkina O.A.
Organization: Saratov State Medical University
Summary:

This study presents the clinical case of pustular psoriasis in a child. This type of disease is a rare variant of derma-toses in childhood. Due to abnormality of rash localization a differential diagnosis was applied with contact dermatitis, staphylococcus impetigo and rubromycosis.

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Characteristics study of cardiac neuropathy formation in patients with metabolic syndrome and carbohydrate metabolism disturbance (according to cardiac rhythm variability analysis data)

Year: 2011, volume 7 Issue: №1 Pages: 079-083
Heading: Internal Diseases Article type: Original article
Authors: Minakov E.V., Kudaeva L.A.
Organization: Voronezh State Medical University n.a. N.N. Burdenko, Railway Clinical Hospital ad st. Voronezh-1
Summary:

The research goal is to study the aspects of cardiac neuropathy (CN) of early formation in patients with metabolic syndrome (MS) and carbohydrate metabolism malfunction according to the data of cardiac rhythm variability analysis (CRV). Vegetative status assessment in patients with MS and glucose tolerance disturbance (GTD), MS and type 2 diabetes mellitus (DM-2) has been done relying on the investigation of CRV analysis conventional features, such as RMSSD, pNN50, new approach application based on the determination of rhythmogram short period variations (RSPV), and average rhythmogram variations (RWMV). RSPV monotony raise failure has been revealed by decrease of heart contraction rate in patients with MS and GTD, MS and DM-2. Considerable decrease of RWMV has been observed in patients with MS and DM-2. RWMV values determined within 24 hours have been diminished in the morning in patients with MS and DM-2 and normal at night. RMSSD and pNN50 features have appeared to be significantly diminished in patients with MS and DM-2, they ranging within the normal readings in patients with MS and GTD, though in the morning pNN50 values have been found at the lower tolerance. Primary and completely reversible manifestations of CN have been revealed in patients with MS and GTD; new RWMV feature has been noted to have advantages over the conventional characteristics when diagnosing the signs of CN in patients with MS and GTD

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The investigation of cardiac neuropathy formation characteristics in patients with metabolic syndrome and carbohydrate metabolism malfunction (according to the data of cardiac rhythm variability analysis)

Summary:

Aims: To study the aspects of cardiac neuropathy (CN) early formation in patients with metabolic syndrome (MS) and carbohydrate metabolism malfunction according to the data of cardiac rhythm variability analysis (CRV). Vegetative status assessment in patients with MS and glucose tolerance disturbance (GTD), MS and type 2 diabetes mellitus (DM-2) has been done relying on the investigation of CRV analysis conventional features, such as RMSSD, pNN50, new approach application based on the determination of rhythmogram short period variations (RSPV), and rhythmogram weighted-mean variations (RWMV). RSPV monotony rise failure has been revealed on decrease of the heart contraction rate in patients with MS and GTD, MS and DM-2. Considerable decrease of RWMV has been observed in patients with MS and DM-2. RWMV values determined within 24 hours have been diminished in the morning in patients with MS and DM-2 and normal at night. RMSSD and pNN50 features have appeared to be significantly diminished in patients with MS and DM-2, they ranging within the normal readings in patients with MS and GTD, though in the morning pNN50 values have been found at the lower tolerance. Primary and completely reversible manifestations of CN have been revealed in patients with MS and GTD; new RWMV feature has been noted to have advantages over the conventional characteristics when diagnosing the signs of CN in patients with MS and GTD

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201003_582_585.pdf248.75 KB