Saratov JOURNAL of Medical and Scientific Research

Review

Main markers of vascular endothelium dysfunction in primary open-angle glaucoma

Year: 2018, volume 14 Issue: №4 Pages: 820-824
Heading: Ophtalmology Article type: Review
Authors: Nugmanova A.R., Zagidullina A.Sh.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

The review presents current literature data on the functions of the vascular endothelium, its role in the pathogen-esis of vascular pathologies, as well as the main markers of its dysfunction. Vascular endothelium plays a role in the development of thrombosis, angiogenesis, remodeling of the vascular wall. It is involved in the regulation of vascular tone, local hemostasis, proliferation. The results of clinical studies of the endothelium capacity, which disorders may accompany primary open-angle glaucoma and contribute to the progression of glaucomatous optic neuropathy, are presented here.

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Study of the change in the volume of accommodation in students with visual load using Tonoref III (Nidek, Japan)

Year: 2018, volume 14 Issue: №4 Pages: 808-811
Heading: Ophtalmology Article type: Review
Authors: Hanova J.I., Nabiullin A.R., Avhadeeva S.R., Azamatova G.A.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Purpose: to evaluate the volume of accommodation in students with the help of Tonoref III (Nidek, Japan) apparatus before and after the visual load, and also to identify the correlation of the volume of accommodation with the refraction indices and papilla size. Material and Methods. We investigated 204th year students of BSMU who passed the test of accommodation and refraction on the device Tonoref III (Nidek, Japan) 10 minutes before and immediately after a lecture. Results. We identified that the accumulative response after the exercise was weakened and clinical refraction was increased. The accommodation afterthe load was decreased. By reducing the amount of accommodation revealed an increase in the diameter of a pupil. Students with less severe refractive disorders showed a stronger increase in clinical refraction after exercise than students with moderate to high degrees of myopia. Conclusion. We concluded that the load reduces the absolute volum of accommodation, and this, in turn, leads to an increase in clinical refraction, dilated pupil and reduced visual acuity. Students with emmetropia and mild myopia are particularly susceptible to the above-mentioned changes.

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Differential approach to the diagnosis of dry eye syndrome in an outpatient setting

Year: 2018, volume 14 Issue: №4 Pages: 795-799
Heading: Ophtalmology Article type: Review
Authors: Azamatova G.A., Aznabaev М.Т., Gaysina G.Ya.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Due to the high prevalence of dry eye syndrome (DES) among patients ophthalmologists need in an outpatient setting in a real equipment quickly and accurately diagnose this disease to provide successful and effective treatment. The article summarizes the experience of clinical use. traditional research methods for dry eye syndrome (slit lamp inspection, biomicroscopy using vital dyes; Schirmer's test, Norn's test or test to determine the time of tearing of the tear film) in ambulatory conditions reception of the ophthalmologist. This review presents the most optimal algorithm for examination of patients with DES. The authors of the article pointed to the most informative diagnostic methods for detecting changes in each of the layers of the tear film.

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Transfollicular drug delivery: current status of the problem

Year: 2018, volume 14 Issue: №4 Pages: 735-737
Heading: Dermatovenerology Article type: Review
Authors: Talnikova Е.Е., Svenskaya Yu.l., Dobdina A.Yu., Morrison A.V., /UtzS.R./
Organization: Saratov State Medical University
Summary:

The review is dedicated to one of the promising areas in medicine —transfollicular drug delivery. The article presents
literature data on working principles of this route of administration, main practical aspects and future prospects for its
use.

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Medical and organizational issues of patients' preoperative fears management (analytical review)

Year: 2018, volume 14 Issue: №4 Pages: 686-690
Heading: Sociology of Medicine Article type: Review
Authors: Fedonnikov A.S., Katkova A.V., Andriyanova E.A.
Organization: Saratov State Medical University
Summary:

 The article deals with the problem of preoperative patient fears. Specific characteristics of preoperative fears and the mechanisms of their occurrence were described. According to the scientific literature analysis the typology of preoperative fears was performed. Within the framework of the author's approach the directions of the following theoretic understanding and practical solutions of indicated problem were presented. They included health managers focusing on interpersonal communication of patient and medical specialist; further analysis of factor influencing interpersonal communication of patient and medical specialist under disease condition requiring surgery; development of psychologically based medical care and postoperative rehabilitation quality indicators.

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The value of tumor markers in prognos-ing the outcomes of treatment of patients with bladder cancer

Year: 2018, volume 14 Issue: №4 Pages: 661-666
Heading: Urology Article type: Review
Authors: Ponukalin A.N., Zakharova N.B., Skriptsova S.A., Fomkin R.N., Chekhonatskaya M.L.
Organization: Saratov State Medical University n.a. V I. Razumovsky, Scientific Research Institute of Fundamental and Clinical Uronephrology, Saratov State Medical University
Summary:

The review analyzes the recent publications of the results of the use of molecular genetic markers of bladder cancer (RMP) in clinical practice. The prospects of application of a series of molecules determined in tumor tissue, serum, urine in the diagnosis of RMP are presented. One ofthe most promising areas of finding a marker forthe diagnosis and control of treatment of RMP in recent years are the study ofthe proteomic composition of urine.

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Etiopathogenetic aspects of development of a microbial eczema

Year: 2018, volume 14 Issue: №4 Pages: 651-656
Heading: Skin Diseases Article type: Review
Authors: Tlish M.M., Popandopulo Е.К.
Organization: Kuban State Medical University
Summary:

The relevance of studying of an etiology and pathogenesis of a microbial eczema is caused by the fact that it is one of the most widespread chronic dermatosises which exerts stress impact and leads to essential restrictions in all spheres of activity of the person. In the last decade earlier beginning of a dermatosis, the increasing weight, synchronization of a current with a frequent long recurrence, the considerable distribution of skin pathological process and also formation of resistance to the standard methods of therapy is noted. The data of the Russian and foreign authors concerning the main questions of an etiology and a pathogenesis of a microbial eczema are presented in the review. The epidemiology of this pathology in population is described. Connection of a microbial eczema with influence of microorganisms, violation of work of digestive tract, is analyzed by an angiopathy, pathology of endocrine and nervous systems; changes of the immune answer are noted.

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The methods of deep periprosthetic infection diagnostics in the area of knee joint

Year: 2018, volume 14 Issue: №3 Pages: 607-610
Heading: Traumatology and Orthopedics Article type: Review
Authors: Shpinyak S.P., Babushkina I.V., Maksyushina T.D., Galashina E.A., Chibrikova Yu.A., Bondarenko A.S., Norkin I.A.
Organization: Saratov State Medical University
Summary:

The data on the methods and promising areas of investigations potent to improve diagnostic tactics in patients with infectious complications after total knee replacement is presented.

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The epidemiology of spine and spinal cord injuries

Year: 2018, volume 14 Issue: №3 Pages: 592-595
Heading: Traumatology and Orthopedics Article type: Review
Authors: Tolkachev V.S., Bazhanov S.P., Ulyanov V.Yu., Fedonnikov A.S., Ninel V.G., Salikhu Kh., Norkin I.A.
Organization: Saratov State Medical University
Summary:

The article contains domestic and foreign data reflecting epidemiological peculiarities of traumatic injuries of spine and spinal cord, their character and incidence among various population groups with respect to gender and age parameters. The study outlines spine and spinal cord injury structure with regard to modern classification schemes, introduces injury incidence data, specifies indexes of lethality in spine and spinal cord injuries.

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Chronic non-specific back pain: patho-genetic substantiation of manual therapy

Year: 2018, volume 14 Issue: №3 Pages: 570-574
Heading: Traumatology and Orthopedics Article type: Review
Authors: Medentsov V.A., Komleva N.E., Goncharenko I.M., Danilov A.N., Chekhonatskiy A.A.
Organization: Saratov Scientific Research Institute of Agricultural Hygiene
Summary:

We presented the review of data from MEDLINE, EMBASE, CINAHL on the mechanisms of therapeutic activity of manual therapy, as well as on studied tissue and systemic responses, and the elaborations on the issue of manual treatment choice in chronic non-specific back pain.

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