Saratov JOURNAL of Medical and Scientific Research

Moscow Central Hospital № 6, Head of Endoscopic Ward

Respiratory tests in diagnostics of Helicobacter pylori infection

Summary:

The Research Objective: Comparative assessment of informational content of various techniques, respiratory tests for Helicobacteriosis detection. Methods et methods: Research of existence of H.pylori in stomach has been conducted by respiratory tests in 106 patients with various diseases of stomach and duodenum. All researches have been conducted on an outpatient basis. Esophagogastroduodenoscopy with mucous biopsy and determination of H.pylori in biopsy materials have been followed by respiratory tests. Respiratory tests 13C UBT and 14C UBT have been carried out. The comparative analysis of respiratory tests for Helicobacteriosis detection has been performed. Results: The conducted researches have showed that, the respiratory tests are favourable for H.pylori diagnostics. They are methodically simple and short-term. Conclusion: Results of comparative researches showed that ammoniac respiratory tests for Helicobacteriosis detection in stomach possess lesser sensitivity than the 13C UBT — respiratory test and may be used for the primary diagnostics which results demand carrying out additional methods of diagnostics. Low specificity of these techniques and inauthentic results do not control the efficiency of eradication of H.pylori and do not present any value in medical examination of the population.

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Immunological and morphological aspects of diagnostics of Helicobacter pylori infection and Herpesviridae viruses

Year: 2010, volume 6 Issue: №2 Pages: 360-364
Heading: Infectious Diseases Article type: Original article
Authors: N.G. Dudaeva, V.B. Grechushnikov, I.O. Bugaeva, G.N. Tarasova, T.V. Golovacheva
Organization: Saratov State Medical University, Rostov State Medical University, Moscow Central Hospital № 6, Head of Endoscopic Ward
Summary:

100 patients with inflammatory diseases of gastrointestinal tract were examined. Microbial component of inflammation process was detected by means of polymerase chain reaction (PCR). By means of PCR etiological microbial factor of mononuclear cells in peripheral blood (MCPB) was investigated. Mixtinfication of mucosa membrane of gastrointestinal tract with H. pylori and Herpesviridae in pathology of gastroduodenal area and presence of fragments of microorganisms DNA in PBMC were revealed. This phenomenon may be important in pathogenesis of pathology of gastrointestinal tract and forms the basis for its further investigation

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