Saratov JOURNAL of Medical and Scientific Research

Bazhanov S.P.

Scientific Research Institute ofTraumatology Orthopedics and Neurosurgery, Saratov State Medical University n.a. V.I. Razumovsky Department of Innovations in Vertebrology and Neurosurgery, Senior Research Assistant, Candidate of Medical Science

The epidemiology of spine and spinal cord injuries

Year: 2018, volume 14 Issue: №3 Pages: 592-595
Heading: Traumatology and Orthopedics Article type: Review
Authors: Tolkachev V.S., Bazhanov S.P., Ulyanov V.Yu., Fedonnikov A.S., Ninel V.G., Salikhu Kh., Norkin I.A.
Organization: Saratov State Medical University
Summary:

The article contains domestic and foreign data reflecting epidemiological peculiarities of traumatic injuries of spine and spinal cord, their character and incidence among various population groups with respect to gender and age parameters. The study outlines spine and spinal cord injury structure with regard to modern classification schemes, introduces injury incidence data, specifies indexes of lethality in spine and spinal cord injuries.

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The peculiarities of morphological differential diagnostics of intradural tumor localized at the level of medullary cone and cauda equina roots

Year: 2018, volume 14 Issue: №3 Pages: 567-570
Heading: Traumatology and Orthopedics Article type: Case report
Authors: Matveeva O.V., Bazhanov S.P., Ponomareva Е.Е., Tolkachev V.S.
Organization: Penza Regional Oncology Centre
Summary:

Aim: to demonstrate the necessity of modern methods of morphological verification in the differential diagnostics of primary and secondary neoplastic lesion of spinal cord. It is shown that histogenesis of tumor cells should be regarded from the viewpoint of comparative assessment of traditional and complementary methods of morphological verification that outlines the necessity of complex differential morphological diagnostics with apparent priority of immunohisto-chemical methods for the verification of final diagnosis of metastatic lesion in a rarely seen localization.

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Long-term results of posterior anchorage of subaxial vertebra in acute unstable trauma

Year: 2018, volume 14 Issue: №3 Pages: 501-504
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Bazhanov S.P., Ulyanov V.Yu., Ostrovskiy V.V., Likhachev S.V.
Organization:
Summary:

Aim: to study long-term results of posterior anchorage of subaxial vertebra in acute trauma. Material and Methods. We conducted an analysis of long-term results of posterior anchorage of subaxial vertebra in 17 patients with acute unstable trauma which had undergone complex clinical neurological and instrumental investigation, surgical treatment performed from dorsal approach, and the estimation of long-term results in preoperative period. Results. The obtained data indicate the method of transarticular anchorage to be effective and safe and not to have any negative effect on biomechanical properties of cervical spine in the long-term postoperative period. Conclusion. The use of posterior anchorage in acute unstable trauma is most reasonable in subaxial injuries accompagnied by the deformities of medial and posterior spinal columns.

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The tactics of surgical treatment in metastatic lesions of upper cervical spine.

Year: 2018, volume 14 Issue: №3 Pages: 498-501
Heading: Traumatology and Orthopedics Article type: Case report
Authors: Bazhanov S.P., Gulyaev D.A., Ulyanov V.Yu., Ostrovskiy V.V., Tolkachev V.S.
Organization: The Almazov National Medical Research Centre, Head of Second Cerebral and Spinal Cord Tumors Department, Doctor of Medical Sciences
Summary:

We demonstrated a successful case of surgical treatment of the patient with metastatic lesion of upper cervical spine with respect to multidisciplinary approach. We performed simultaneous two-stage surgical intervention, the first stage being occipitospondylodesis by multi-segment construction; and second —tumor resection from expanded combined access. It has been stated that the proposed surgical tactics allows performing curative resection in one surgical session without neurological deficit buildup in the postoperative period.

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Professor I.Ya. Livshits and his contribution to the development of national neurosurgery

Summary:

The article traces the professional path of Professor Lev Yakovlevich Livshits, assesses his scientific contribution to the development of national neurosurgery. The concept of minimally invasive surgical treatment of trigeminal nerve neuralgia, developed by L. Ya. Livshits, allowed developing an original method of puncture surgical treatment of pain syndrome by directed hydrothermal destruction of the sensitive trigeminal root. The concept of "growing radicalism" created by Professor L. Ya. Livshits allowed his students elaborating algorithms for treating severe chronic pain syndromes of any localization and etiology.

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Comparative retro- and prospective analysis of treatment outcomes in patients with SCI and cervical spine injuries in acute and early periods of traumatic disease

Year: 2017, volume 13 Issue: №3 Pages: 710-715
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Bazhanov S.P., Ulyanov V.Yu., Chibrikova Yu.A., Biryukova A.V., Norkin I.A., Gulyaev D.A., Salihu H.
Organization: Almazov National Medical Research Centre, Saratov State Medical University
Summary:

The aim: to conduct comparative retro- and prospective study of treatment outcomes in patients with cervical spine and SC injuries on the basis of assessment scale analysis. Material and Methods. 217 patients with closed cervical spine and SC injuries commeasurable by age, degree of neurological deficit, acute physiological and chronic state disorders were enrolled into the study. 177 patients comprised the main group (prospective study) and 40 — comparison group (retrospective study). To compare treatment outcomes we used Karnofsky score (Karnofsky, 1949), a quantitative assessment score for general patient status scales, APACHE II, Acute Physiology and Chronic State Evaluations (Knaus — Draper, 1985) and SCIM II, Spinal Cord Independence Measure Scale. Results. Comparative analysis based on the quantitative values of assessment scales, indicates an improvement of short-term treatment outcomes in patients with SC and cervical spine injuries in the main group. Conclusion. Complex approach to differentiated surgical treatment management and unique neuroprotection methods significantly improves short-term treatment outcomes having positive effect on general patient status, severity of acute physiological and chronic state disorders and patients' independence in the post-surgical period.

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A comprehensive evaluation of cervical spine surgery outcomes

Year: 2017, volume 13 Issue: №2 Pages: 266-273
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Ostrovsky W, Schanitsyn IN, Bajanov SP, Fedonnikov AS.
Organization: Saratov State Medical University
Summary:

Aim: study of diagnostic value of different assessment scales to evaluate outcomes of surgeries in degenerative and post-injury deformities of cervical spine. Material and Methods. Between January and December 2015, 110 consecutive patients with degenerative and traumatic lesions of cervical spine were selected for surgery and results of treatment were followed. Preoperatively and 12 months postoperatively the patients filled in a questionnaire that included a VAS, Odom's scale, NDI, modified JOAand the Zung Depression Scale. To assess the results of the intervention, the concept of "effect size" was used. Distribution of different scores classified according to Odom's criteria as excellent/good and fair/poor. Results. All scores improved in all group of patients. For VAS, NDI and modified JOA scores the effect size was largest. NDI, JOAand ZDS seemed to correlate well with the classification of outcome by Odom. Conclusion. It is suggested many scales to assess the outcomes of the cervical spine surgery based on different criteria; nevertheless, there are no generally accepted and validated methods that can be used to analysis the outcome of cervical spine surgery. We conclude that investigated

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Correction of immune disorders in patients with malignant tumors at level of craniovertebral junction and upper cervical spine

Year: 2013, volume 9 Issue: №2 Pages: 295-301
Heading: Oncology Article type: Original article
Authors: Bazhanov S.P., Uljanov V.Yu., Norkin I.A., Gulyaev D.A.
Organization: Russian Scientific Research Institute of Neurosurgery n.a. Professor A. L. Polenov
Summary:

Objective: To study the cellular and humoral immunity in patients with malignant tumors of the upper cervical spine. Material and methods: The study included 22 patients with malignant tumors of the craniovertebral junction and upper cervical spine. To assess the function of the immune system the methods of population and subpopulation immuno-phenotyping of peripheral blood lymphocytes have been applied. Cytokine parameters and functional status (cytotoxic) activity of NK-cells have been studied using immunofermental methods. The indices have been presented in absolute and relative terms. All the patients have been subjected to the adjuvant therapy. Results: Correction of cellular immunity has led to significant increase in CD3 + (T-lymphocytes) and CD3 + CD8 + (T-killers). Cytokine levels in the groups studied in the dynamics have not been significantly altered. The changes of cytotoxic (functional) activity of NK-cells in the first group after the combined treatment have been considered to be higher than before the treatment. Cytotoxic index of (functional) activity of NK-cells in the second group under the study after the combined treatment has been determined to be lower than before the treatment. Conclusion: It has been found out that the application of complex treatment accompanied by immunotropic therapy may positively influence the immune status.

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Features of the reaction of hourly haemostasis against the background of hyperbaric oxygenation patients with complicated spinal cord injuries

Year: 2013, volume 9 Issue: №1 Pages: 82-87
Heading: Neurology Article type: Original article
Authors: Shchukovsky V.V., Ulianov V.Yu., Bazhanov S.P.
Organization:
Summary:

Purpose: to improve the treatment results of patients with complicated injuries of the cervical spine on the basis of an hourly study of the reaction of the hemostatic system after the application of hyperbaric oxygenation. Materials and Methods. The subject of the study were 12 patients with complicated closed cervical spine trauma. In the study group characteristics were studied hourly reaction of the hemostatic system during treatment with hyperbaric oxygenation. Results. Found that patients with traumatic spinal cord disease, changes in the hemostatic system in the form of a coherent structural and phase changes in the structural chronometric anticoagulation and chronometric hypercoagula-bility, activation and inhibition of fibrinolysis, and reduced the extent of time and the overall rate of platelet aggregation. Conclusion. Under the influence of hyperbaric oxygenation in patients with traumatic spinal cord disease arise adaptive changes in the regulation of blood aggregation.

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Коррекция трофологической недостаточности у больных с синдромом компрессионной миелопатии различной этиологии на уровне верхнешейного отдела позвоночника

Year: 2012, volume 8 Issue: №3 Pages: 825-830
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Bajanov S.P., Uljanov V.Yu., Ostrovsky V.V., Shchukovsky V.V., Makarkina E.V., Uljanova E.V.
Organization:
Summary:

Objective: To improve the treatment results of patients with traumatic injuries, and neoplastic lesions of the upper cervical spine on the basis of a differentiated algorithm of nutritional-metabolic therapy. Materials and methods: Based on clinical and instrumental methods of examination typical metabolic characteristics have been studied in 21 patients with compressive myelopathy at the level of the upper cervical spine. Results: Due to the received data differentiated algorithm of nutritional-metabolic therapy has been worked out. Conclusion: The use of nutritional-metabolic therapy in patients with compressive myelopathy at the level of the upper cervical spine may improve the treatment.

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