Neurology

Treatment alcoholic polyneuropathy is one of the most important challenges of health care not only in Russia, but throughout the world. Material and methods. A comparison study of efficacy and tolerability ofthefarmacopuncture in 58 patients with alcoholic polyneuropathy [36 (62,1%) male, 22 (37,9%) female, mean age 41,5±12,4 years]. Introduction of thiamin (vitamin B1) in BAP of the cohort studied was accompanied by a positive dynamics of both subjective and objective clinical symptoms. By means of standard ENMG methods the study was made of motor fibrae of median, tibia, fibular and sensory fibrae of median nerves. Results. Farmacopuncture is tolerable and safe. Conclusions. The results of the study confirm an assumption of introduction of thiamin in БАТ efficacy in alcoholic polyneuropathy and allow to recommend the drug for a wide clinical application.

The article presents a detailed review on epidemiology, pathogenesis and interrelation of serotonin neuromedia-tor metabolism in the central nervous system in state of chronic pain and depression. It has been demonstrated that neurophysiological conditions serve as psychological defense of an individual. That mechanism has been proved to «transform» serious emotions onto the inner level (body) and it assists in the development of psychosomatic disorders — chronic pain syndrome

This paper presents the results of a survey of 50 patients to study the application of terahertz therapy of NO in the complex treatment of postoperative lumbar radiculopathy localization. Materials and methods. Using a visual analogue scale assessed the degree of regression of pain, depending on the nature of the therapy. For the diagnosis of intra-articular inflammation in the postoperative motor segment and a local mikrovaskulita determined the level of antibodies in the serum of patients to collagen and myeloperoxidase. The results suggest shortening pain and reducing the content of antibodies to MPO and collagen in patients receiving short-wave therapy. Therefore, we conclude that the use of NO therapy TGCH improves the treatment of postoperative lumbar radiculopathy localization

The aim of the study: To examine the sensitivity of mini-mental state examination (MMSE) and clock drawing test (CDT) in screening of cognitive function in patients with syphilis. Materials and methods A total of 1387 patients with different forms of documented neurosyphilis were examined to study the deficiency of neurological function. The diagnosis of neurosyphilis was confirmed by CSF-study. In 75 cases cognitive function was studied by MMSE and clock drawing test. Results: MMSE and clock drawing test showed cognitive dysfunction in 76,4% of patients with syphilis. The sensitivity of both tests was rather equal. Such tests could be made in a short time and are simple in understanding. Thus these tests could help in the everyday practice of dermatologists and neurologists as screening methods of cognitive dysfunction in patients with syphilis. Conclusion: The results of screening tests in patients with significant cognitive dysfunction could be used in the early diagnostics and corresponding treatment of neurosyphilis

Postural abnormalities are clinical syndromes that lead to disability in patients with Parkinson's disease. The aim of the study is to investigate the characteristics of postural control in different clinical forms of Parkinson's disease using a computer stabilometer examination. Materials and Methods: Clinical and neurophysiological analysis has been performed in 148 patients with Parkinson's disease who have been divided into groups with akineticorigid, shaking-rigid and shaking forms of the disease. All patients have experienced static stabilometer examination with medical-diagnostic complex «MBN-Biomechanics» (Scientific-Medical Firm MBN, Moscow). Results of the research have proved a significant decrease of compensatory abilities of balance maintenance and the basic standing without dependence on the clinical form of disease. It has been noted that a number of indices have been increased. It has been revealed, that the tremor at rest has influenced significantly the values of such indices. Dissociation between the clinical severity of postural instability and stabilometer indicators reflecting the state of the vertical balance of the body has been revealed. The study has confirmed the importance of the differentiated approach to stabilometer analysis in patients with different forms of Parkinson's disease. Conclusion: Computer stabilometry makes possible the detection of disturbances in postural functions and estimation of their condition in dynamics

Aim. The study was undertaken to identify the features of neurological and cognitive changes in idiopathic epilepsy based on neurological and neuropsychological research. Methods. A total of 105 patients with idiopathic epilepsy at the age of 16 to 45 years. In orderto identify features neuropsychological disturbances, all patients were systematized by the nature and frequency of seizures. Results. As a result of the work identified major the nature neurological and neuropsychological symptoms and syndromes of primary stages of encephalopathy in patients with idiopathic epilepsy

Aim: to analyze the influence of antihypertensive therapy (AT) on clinical and psychological characteristics of patients with hypertensive encephalopathy (HE). Materials: 107 patients with HE l-lll were given inadequate AT and therefore were under the study. Diurnal blood pressure monitoring (DBPM), neurological status, asthenic disorder level, life quality (LQ) parameters, sleep quality and attitude-to-disease type were estimated. The patients were re-examined in 6-month period after prescribing an adequate AT. The control group included 30 healthy patients. Results: in the process of AT daily average indices of blood pressure (BP) were able to be matched with the control indices, the number of patients with normal degree of night BP decrease raised. Physical and psychological health constituents were increased. Sleep quality improved. The increase of patients with well-balanced attitude-to-disease type was fixed. Resume: the use of the modern antihypertensive drugs affects the clinical and psychological characteristics of HE patients positively

The research goal is to evaluate the epidemiology of syphilis and neurosyphilis in the Saratov region science 1994 till 2010. Materials and methods: The forms of statistical inquiry in the Saratov region have been studied. The results of syphilis blood tests were examined in neurological departments of Saratov hospitals. Results: The tendency to reduction of syphilis morbidity was revealed in the Saratov region while the incidence of neurosyphilis increased. Severe forms of symptomatic neurosyphilis were predominant. In spite of increasing number of positive syphilis serological tests in neurological hospitals of Saratov the detection of neurosyphilis among neurological patients remained low. Conclusion: Neurosyphilis has become a common disease in the Saratov region. The issues of diagnostics and treatment of neurosyphilis should be considered by close cooperation between dermatologists and neurologists

Aim: To evaluate the possibilities of the magnetic resonance tomography (MRT) in diagnostics and identification of neurosyphilis. Materials and methods: A total of 1387 patients with different forms of documented neurosyphilis were examined to study the deficiency of neurological function. The diagnosis of neurosyphilis was confirmed by CSF-study. MRT was performed in 57 cases. Results: Magnetic resonance tomography (MRT) in 6 patients showed no pathology, 16 patients had arachnoid cystic changes and in 16 cases hydrocephaly occurred. Cerebral cortical atrophy was presented in 13 patients, in 12 cases — multifocal changes were visualized, 12 patients had white matter structural changes. Two cases required diagnostics. A 59-year-old man was hospitalized with epileptic seizure, progressive dementia and multifocal neurologic symptoms. A 40-year-old man was examined with recurring episodes of acute cere-brospinal accident and progressing cognitive disorders. Conclusion: MRT could be used in differential diagnostics of neurosyphilis imitating space-occupying lesions of cerebrum and spinal cord, tumors of central nervous system and could help to define the form of neurosyphilis

This article deals with the factors influencing the process of medico-social rehabilitation of patients with borderline mental disorders in modern society. Approaches to rehabilitation of population mental health are also considered. The results of the research of medico-social aspects of patients with the borderline mental disorders rehabilitation, directed on correction of life quality indicators which size is defined by infringements of mental condition and socialization of patients are described. The research proves that priority directions of medico-social rehabilitation at the given category of patients are defined by pathological changes in psychological sphere, social relations and environment