Saratov JOURNAL of Medical and Scientific Research

prognosis

Perioperative complications in patients with high anaesthetic and operating risk (review, part II)

Year: 2012, volume 8 Issue: №1 Pages: 051-057
Heading: Anaesthesiology and Reanimatology Article type: Review
Authors: Sadchikov D.V., Prigorodov M.V., Vartanjan T.S.
Organization: Saratov State Medical University
Summary:

The article presents the literature review on perioperative complications that have been systematized. The prognosis of perioperative complications has been proved

AttachmentSize
201201_051-057_.pdf343.86 KB

Prognosis and diagnostics for placental insufficiency according to markers of endothe-lial dysfunction, deciduation, apoptosis and cellular proliferation

Year: 2011, volume 7 Issue: №1 Pages: 052-059
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Lipatov I.S., Tezikov Yu.V.
Organization: Samara State Medical University
Summary:

Objective. The research goal is to estimate prognostic and diagnostic possibilities of markers of endothelial dysfunction, deciduation, apoptosis and cellular proliferation concerning realization of placental insufficiency. Material. 154 women of high risk group of severe placental insufficiency development have been examined in dynamics of the second and third trimesters of pregnancy. 30 healthy pregnant women have made the control group. Research methods are clinical, immunological, instrumental. Results. It is established that prognosis and early diagnostics for severe placental insufficiency can be carried out with application of monitoring of the maintenance of endothelial dysfunction markers, placental fibers of a mother placenta membrane, apoptosis and cellular proliferation in blood. In the second trimester of pregnancy prognostically significant criteria have included an increase of an index of cytotoxicity of antien-dothelial antibodies, the general IgE, lymphocytes, expressing Fas/APO-1/CD 95-receptor, TNFb and decrease of FGP. Conclusion. Therefore the forms of realization and severity level of placental insufficiency have been caused by the beginning and degree of damages in adaptation of endothelial systems, activation of the immunopathological reactions in the placenta manifested by trophoblastoma programmed cellular destruction of lymphocytes

AttachmentSize
201101_052-059.pdf281.47 KB

New approach to surgery in obliterating atherosclerosis of lower limb arteries

Year: 2010, volume 6 Issue: №4 Pages: 850-856
Heading: Surgery Article type: Original article
Authors: Kazantsev A.M., Korymasov E.A.
Organization: Samara State Medical University
Summary:

Complex examination of 296 patients with obliterating atherosclerosis of lower extremities was carried out. Prog-nostically significant clinical, hemodynamic, hemostatic, immunological characteristics, markers of endothelial dysfunction and changes in lipid profile in patients were studied. Pathogenetic system of disease prognosis was worked out as a result of multifactor analysis where the index of course of disease was accounted. When the index was lower than + 13, obliterating atherosclerosis was not considered as progressive. Progressive atherosclerosis was determined with the index over the point +13

AttachmentSize
201004_850_856.pdf290.18 KB

Important issues of alcoholic liver disease prognosis

Year: 2010, volume 6 Issue: №1 Pages: 094-100
Heading: Internal Diseases Article type: Review
Authors: S.P. Sernov, V.B. Lifshitz, Yu.I. Skvortsov, V.G. Subbotina, A.G. Martynova, L.S. Sulkovskaya, V.I. Shulgin, L.A. Suchilina
Organization: Saratov State Medical University, Saratov Psychiatric Hospital
Summary:

Alcoholic liver disease prognosis has not been thoroughly developed yet. The possibility of morphologic prognosis has been limited due to disadvantages of liver biopsy. Insignificant amount of studies is devoted to laboratory methods. prognosis value of serum markers of liver fibrosis at the last cirrhotic stages is widely considered in the medical literature. at the same time the results of treatment are determined by making a diagnosis

AttachmentSize
201001_094_100.pdf363.97 KB