Saratov JOURNAL of Medical and Scientific Research

Kemerovo State Medical University

Comparative analysis of efficiency of two techniques of endoscopic organ sparing surgery at ectopic tubal pregnancy

Year: 2019, volume 15 Issue: №1 Pages: 14-18
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Fetisheva L.E., Mozes V.G., Mozes K.B.
Organization: Kemerovo State Medical University
Summary:

Aim: to compare the effectiveness of salpingostomy with the subsequent evacuation of the ovum and the resection of a part of the ampulla of the fallopian tube with the ovum and the subsequent neostomatoplasty in the treatment of tubal pregnancy. Material and Methods. A retrospective randomized study of the effectiveness of two techniques of endoscopic organ-sparing surgical treatment of ectopic tubal pregnancy was conducted. Results. The time for performing salpingostomy and resection was 11.8±1.5 minutes and 21±2 minutes, respectively (U[12458]=0, p=0.001). Compared with salpingostomy, the thread did not lead to the appearance of a trophoblast, which was accompanied by a decrease in the degree of adhesions in the pelvis in the third month of observation (PAI showed 2 (2; 2) and 0 (0; 1) points, respectively U =759, p=0.001; R-AFS corresponded to the minimum degree of severity: 2(0; 2) and 0 (0; 0) points, respectively (U4 =1076, p=0.001); according to the modified classification of the degree of adhesions in the pelvis after cesarean section corresponded to the minimum degree of severity: 4 (0;4) and 0 (0;4) points, respectively (U[12458]=2617, p=0.006)and more frequent the operated fallopian tube (30.6% and 58,6%, respectively, p=0.001)was accompanied by a more frequent onset of spontaneous uterine pregnancy by the 12th month of observation (12.9% and 29,3%, respectively, p=0.007) and delivery to 18 months of observation (3.2% and 15.5%, respectively, p=0.001). Conclusion. Despite the higher technical complexity, resection of a part of the ampulla of the fallopian tube with a fetal egg and subsequent neostomatoplasty is an effective alternative to salpingostomy andmay be used in women with an ectopic pregnancy wishing to preserve reproductive function.

AttachmentSize
2019_1_014-018.pdf386.96 KB

Comparative analysis of efficiency of two techniques of endoscopic organ sparing surgery at ectopic tubal pregnancy

Year: 2019, volume 15 Issue: №1 Pages: 14-18
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Fetisheva L.E., Mozes V.G., Mozes K.B.
Organization: Kemerovo State Medical University
Summary:

Aim: to compare the effectiveness of salpingostomy with the subsequent evacuation of the ovum and the resection of a part of the ampulla of the fallopian tube with the ovum and the subsequent neostomatoplasty in the treatment of tubal pregnancy. Material and Methods. A retrospective randomized study of the effectiveness of two techniques of endoscopic organ-sparing surgical treatment of ectopic tubal pregnancy was conducted. Results. The time for performing salpingostomy and resection was 11.8±1.5 minutes and 21±2 minutes, respectively (U[12458]=0, p=0.001). Compared with salpingostomy, the thread did not lead to the appearance of a trophoblast, which was accompanied by a decrease in the degree of adhesions in the pelvis in the third month of observation (PAI showed 2 (2; 2) and 0 (0; 1) points, respectively U =759, p=0.001; R-AFS corresponded to the minimum degree of severity: 2(0; 2) and 0 (0; 0) points, respectively (U4 =1076, p=0.001); according to the modified classification of the degree of adhesions in the pelvis after cesarean section corresponded to the minimum degree of severity: 4 (0;4) and 0 (0;4) points, respectively (U[12458]=2617, p=0.006)and more frequent the operated fallopian tube (30.6% and 58,6%, respectively, p=0.001)was accompanied by a more frequent onset of spontaneous uterine pregnancy by the 12th month of observation (12.9% and 29,3%, respectively, p=0.007) and delivery to 18 months of observation (3.2% and 15.5%, respectively, p=0.001). Conclusion. Despite the higher technical complexity, resection of a part of the ampulla of the fallopian tube with a fetal egg and subsequent neostomatoplasty is an effective alternative to salpingostomy andmay be used in women with an ectopic pregnancy wishing to preserve reproductive function.

AttachmentSize
2019_1_014-018.pdf386.96 KB

Complications after different surgical methods of setting polypropylene suburethral meshes in women with stress urinary incontinence

Year: 2018, volume 14 Issue: №2 Pages: 277-280
Heading: Urology Article type: Original article
Authors: Eisenakh I.A., Korotkevich O.S., Mozes V.G., Vlasova V.V.
Organization: Kemerovo State Medical University, Novokuznetsk State Clinical Hospital № 1
Summary:

The aim: to determine the complication's rate, based on a seven-year experience, after the stress urinary incontinence correction in women with different methods of setting suburethral polypropylene meshes. Material and Methods. The analysis of seven years of experience of surgical correction with different methods of setting suburethral meshes in 1260 women with stress urinary incontinence; obturator fixation the mesh inside-outside and outside-inside: supra-pubic fixation the mesh; non-trocar fixation the mesh type mini-sling was carried out. Results. The greatest frequency of complications were identified in the first two years of implementation the setting of suburethral meshes, after that the complication's rate decreased progressively and it was in the range 7-8% the last three years. The frequency of early operative complications at a different setting of suburethral meshes had no statistically significant differences, but there were more the statistically significant intraoperative and mesh-associated complications at suprapubic fixation. Conclusion. The study confirms that the installation of suburethral meshes by the method of suprapubic fixation of mesh is associated with a higher incidence of complications and should be performed only in the target group of patients who are not suitable for surgical correction in safer ways.

AttachmentSize
2018_2_277-280.pdf223.89 KB

Indicators of allogenic interactions of lymphocytes in spouses as additional diagnostic and prognostic criteria of immune forms of reproductive failures

Year: 2013, volume 9 Issue: №4 Pages: 649-652
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Belenkova O.V., Mozes V.G., Shabaldin A.M., Lisachenko G.V.
Organization: Kemerovo Children Hospital № 5, Kemerovo State Medical University
Summary:

Research objective: to search new laboratory approaches to the diagnostics of immune forms of reproductive failures. Materials and methods. Retrospective research a case — control of 54 married couples with idiopathic reproductive failures (in the anamnesis — 3 and more spontaneously interrupted pregnancy in the 4-8th weeks) and 47 married couples having two and more children has been conducted. Results. It has been revealed that at the immune form of reproductive failures increase of cells of level A- mononuclear cells, expression of HLDR takes place that promotes tolerance cancellation to allogenic germs and to immune interruption of pregnancy. At reproductive failures female au-toserum positively influences activation of T-lymphocyte (CD3 +/HLADR +) that may lead to the death of half- allogenic germ. Conclusion. Level of expression of CD3 and HLADR on CD45 + of mixed allogenic mononuclear cells of spouses may serve as a diagnostic significant criterion for revealing immune reasons of reproductive failures.

AttachmentSize
2013-04_649-652.pdf793.74 KB

Spectral analysis of slowly wave activity in able to work patients with cognitive-mnestic deficiency

Year: 2012, volume 8 Issue: №3 Pages: 775-777
Heading: Neurology Article type: Author's opinion
Authors: Ganovich Е.А., Zhestikova M.G., Simenikhin В.A., Sholomov I.I., Makluchenko U.A., Rikhtor T.N.
Organization: Saratov State Medical University, Novokuznetsk Post-graduate Medical Institute, Myski Rehabilitation Centre «Topaz», Kemerovo State Medical University
Summary:

The problem of dementia in the modern medicine has been becoming one of the most actual nowadays. In the foundation of cognitive-mnestic dysfunction in the structure of vibration disease there is a biological action of industrial vibration on the central nervous system as well as on the whole body. The analysis of literature provides data on insufficient study of cognitive-mnestic aspect in the structure of vibration disease and also interaction with affective and anxious sphere in people working in the conditions of vibration impact.

AttachmentSize
201203-775-777.pdf278 KB

Clinical predictors of adverse course of nonspecific bacterial vulvovaginitis at girls born from mothers with dysplasia of connective tissue

Year: 2012, volume 8 Issue: №2 Pages: 214-218
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Kosykh S.L., Mozes V.G.
Organization: Kemerovo State Medical University, Kemerovo Children Hospital № 5
Summary:

Research objective: To define clinical predictors of adverse course of nonspecific bacterial vulvovaginitis (NBV) at girls born from mothers with the undifferentiated forms of dysplasia of connective tissue (UFDCT). Materials: At 157 girls clinical research, bacteriological and bacterioscopy research of leucorrhoea from vagina has been conducted, NBV has been diagnosed at 111 girls. At all girls and at their mothers the immunity has been investigated; at all mothers of girls with NBV phenotypic reveals of UFDCT have been found out. Results: At girls with NBV born from mothers with UFDCT severe course of a disease has been marked; and at mothers with UFDCT and at their children with NBV disorders of humoral immunity have been revealed. Presence of more than 5 stigmas of dysembryogenesis with prevalence of thoracodiaphragmatic, articular, cosmetic syndromes and pathology of organs of vision at mothers of girls with NBV is possible to use as predictors of adverse course of the disease

AttachmentSize
201202_214-218.pdf295.66 KB

Состояние фетоплацентарной системы у беременных с недифференцированными формами дисплазии соединительной ткани, носителей семейства герпес-вирусов

Year: 2010, volume 6 Issue: №3 Pages: 531-535
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Dorohova L.N., Shaboldin A.M., Narolenko L.N., Mozes V.G.
Organization: Kemerovo State Medical University, Kemerovo Clinical Hospital № 3 n.a. M.A. Podgorbunsky, Kemerovo Children Hospital № 5
Summary:

The research goal is to determine the risk of infectious process development in placenta of women with undifferenti-ated forms of dysplasia of connective tissue (UFDCT) by agents - herpes viruses (VHG - virus of herpes simplex and cytomegalovirus).
Persistent infection of VHG was revealed in 133 women in the 1 st trimester of pregnancy. All the patients had phe-notypic manifestations of UFDCT; in the 3d trimester of pregnancy immunogram of the second level, histological study of placenta, identification of antigens of VHG family, serological study of placental blood and isolation of DNA of VHG were carried out. All newborns were clinically and laboratory tested on VHG infection.
As pregnant women with UFDCT had high risk of VHG infection development in placenta, they suffered from placental insufficiency. It resulted in unfavourable perinatal outcomes. VHG infection development was caused by disturbances of cellular immunity.
Key words: undifferentiated forms of dysplasia of connective tissue, virus of herpes simplex, cytomegalovirus, cellular immunity, pregnancy

AttachmentSize
201003_531_535.pdf271.13 KB

Clinical and biochemical manifestations of undifferentiated forms of connective tissue dysplasia in pregnant women with varicose veins of small pelvis

Year: 2010, volume 6 Issue: №1 Pages: 056-060
Heading: Obstetrics and Gynecology Article type: Original article
Authors: N.M. Shibelgut, I.S. Zaharov, V.G. Mozes
Organization: Kemerovo State Medical University
Summary:

Research objective is to define the pathogenesis of varicous veins of small pelvis in women. at Ultrasonic investigation of venous system of small pelvis has been carried out in 290 pregnant women. It revealed 190 patients with varicose veins of small pelvis (VVSP). By means of V.M. Jakovleva's technique phenotypic menifestation of connective tissue dysplasia was determined in all pregnant women. Biochemical manifestations of connective tissue dysplasia were identified by sialic acid level in blood serum, daily excretion of glycosaminoglycans and oxyproline.
High frequency of clinical and biochemical manifestations of undifferentiated forms of connective tissue dysplasia was revealed in pregnant women with VVSP. Patients with VVSP developed tooth and jaw, facial and locomotor damages. Patients with VVSP characterized by visceral undifferentiated forms of connective tissue dysplasia demonstrated by refraction involvement, ventral hernias, flat feet, varicous veins of lower extremities, hypermobile syndrome, mitral valve prolapse of different degree. Biochemical manifestations of undifferentiated forms of connective tissue dysplasia in pregnant women with VVSP were insignificant

AttachmentSize
201001_056_060.pdf380.9 KB