Saratov JOURNAL of Medical and Scientific Research

Mordovian State University

The clinical efficacy of extracorporeal and intravascular hemocorrection methods in psoriasis

Year: 2012, volume 8 Issue: №1 Pages: 081-084
Heading: Skin Diseases Article type: Original article
Authors: Baityakov V.V., Kurkina V.A.
Organization: Mordovian State University
Summary:

Purpose. The study of the influence of extracorporeal and intravascular hemocorrection methods (plasmapheresis, ultraviolet blood radiation, ozonetherapy and its combination) on skin process and life quality in patients with extensive psoriasis. Methods. 253 patients with extensive psoriasis from the age of 18 to 72 have been investigated. PASI (Psoriasis Area and Severity Index) and dermatological index of life quality (DILQ) have been used for treatment assessment. Results. The inclusion of efferent quantum and ozone therapy methods in the complex treatment of psoriasis has promoted to the more rapid and complete positive dynamics of skin process and the improvement of life quality. The use of plasmapheresis and its variations with photomodification or the ozone treatment of returning erythrocyte suspension has been the most effective. Plasmapheresis and its modifications are appropriateto be used in the complex treatment of the patients with severe forms of psoriasis. Conclusion: Further study of efferent quantum and ozone therapy methods and their wider use in psoriasis therapy and other chronic dermatosis seem to be promising.

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The peculiarities of the metabolism processes in patients with the exacerbation of extensive psoriasis

Year: 2011, volume 7 Issue: №3 Pages: 633-636
Heading: Skin Diseases Article type: Original article
Authors: Baityakov V. V.
Organization: Mordovian State University
Summary:

Purpose. The study of some indices of the metabolism in patients with the exacerbation of extensive psoriasis, the investigation of the revealed disorder dependence on the clinical peculiarities of the disease and anamnesis data. Methods. 253 patients with extensive psoriasis from the age of 18 to 72 have been investigated.Some indices of lipid and protein metabolism, medium molecular peptide content, lipid peroxidation and antioxidant protection processes in blood plasma have been studied. Results. Dysproteinemia, the increase of С — reactive protein level, seromucoid, medium molecular peptides, common lipids, triglycerides, the reduction of the level of lipid proteins of high density, the intensification of lipid peroxidation processes and the reduction of antioxidant activity have been marked in blood plasma in patients with the exacerbation of extensive psoriasis. The dependence of some indices of metabolism on the clinical picture and the severity of skin process, age, family history has been revealed. Conclusion. Metabolism disorders in patients with psoriasis are of systemic character. It seems appropriate to carry out a deep study of metabolism indices in patients with psoriasis with the following correction of the revealed disorders

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Effect of progesterone and utrogestan on functional liver condition in patients with dysfunctional uterine bleeding

Year: 2010, volume 6 Issue: №3 Pages: 549-552
Heading: Obstetrics and Gynecology Article type: Original article
Authors: Salekh R.Kh., Peshev L.P., Siprov A.V.
Organization: Mordovian State University
Summary:

The effect of progesterone and utrogestan on protein synthetical, fermentative and chromogenic functions of liver in patients with dysfunctional uterine bleedings (DUB) has been studied. 106 women ages 18 to 44 years with hormonal insufficiency of ovarial yellow bodies were examined. The functional condition of the liver was estimated through the content of protein, albumin, globulin, general bilirubin and its connective and free fractions, alanin - and aspartatami-notrasferase, gammaglutamiltranspeptidase, phosphatase alkaline, general and nonprotein sulfhydric groups in blood. The general and effective concentration of albumin was defined in blood serum. It is shown that the concentration of general protein, albumin, general and nonprotein sulfhydric groups decreased by the increased activity of indicated enzymes in patients. It was accompanied by endogenic intoxication. Progesterone treatment decreased the activity of protein synthetical function of liver reducing endocellular fermentative reactions and increasing the level of endogenic intoxication. Therapy by utrogestan resulted in hyperfermentation in patients with endotoxicosis and hypoproteinemia. Therefore patients with DUB suffered from disorders in metabolic function of liver

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SOME ASPECTS OF INFLUENCE OF DIGESTIVE ORGANS DISEASES ON CLINICAL COURSE OF ISCHEMIC HEART DISEASE

Year: 2008, volume 4 Issue: №1 Pages: 122-127
Heading: Internal Diseases Article type: Short message
Authors: E.U. Eremina, E.V. Shipalkina
Organization: Mordovian State University
Summary:

The article is devoted to some aspects of influence of digestive apparatus diseases (chronic gastritis, a stomach ulcer, chronic cholecystitis) on clinical course ofischemic heart disease. It is revealed, thatthe patients with clinical symptomatology are typically to have extra cardiac hue of painful heart attacks. The patients with influence ofischemic heartdisease and digestive apparatus disorders have sympathetic overbalance of the vegetative one against the background of the parasympathotonia.

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EFFICACY OF SICCINE ACID NITRATES AT ACUTE COMBINED PATHOLOGY

Year: 2008, volume 4 Issue: №1 Pages: 59-63
Heading: Anaesthesiology and Reanimatology Article type: Original article
Authors: S.S. Markiyanova, A.A. Kotlyarov, L.V. Vankova
Organization: Mordovian State University
Summary:

We’ve studied the efficacy of using siccine acid nitrates in clinical course of experimental myocardial infarction and pancreatitis. It was revealed thatanimals with myocardial injury and hypodinamia, siccine acid nitrates put obstacles in the way of increasing activity in the process of peroxide oxidation lipids, and cause moderate activation ofanti-oxidant protection.

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MEMBRANOUS INTESTINAL DIGESTION CHARACTERISTICS IN PATIENTS WITH CHRONIC PANCREATITIS

Year: 2009, volume 5 Issue: №1 Pages: 72-75
Heading: Internal Diseases Article type: Original article
Authors: О.А. Stгокоva, E.J. Eremina
Organization: Mordovian State University
Summary:

The study of enzymes activity of membranous intestinal digestion has been carried out. The condition of ultrastructure of mucous membrane of a small bowel in patients with chronic pancreatitis taking into account duration of disease is presented. It is shown, that signs of lesion of a small bowel in case of chronic pancreatitis are caused by disturbances in the first stage of membranous intestinal digestion, observed at early stages of disease and begin to progress with the disease duration.

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ENDOTOXICOSIS PROBLEM IN OBSTETRIC-GYNECOLOGIC PRACTICE

Year: 2009, volume 5 Issue: №1 Pages: 56-59
Heading: Obstetrics and Gynecology Article type: Original article
Authors: A.N. Chudaikin, M.A. Levina, S.L. Peshev, S.V. Ermolaeva, O.A. Kuzmina, R.Kh. Salekh
Organization: Mordovian State University
Summary:

The level of endogenous intoxication has been studied in 444 patients: with inflammation of uterine appendages (98), dysfunctional uterine bleeding (123); in pregnant women with hypertensive disease (107), with chronic tonsillitis (116). It has been established that the level of endotoxemia depends on nosologic type of pathology. Blood catalase activity may be considered as a universal sign of endogenous intoxication.

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