Saratov JOURNAL of Medical and Scientific Research

metabolic indices

About the influence of non-drug methods of treatment on reducing body weight in patients with metabolic syndrome

Summary:

The research aims to study influence of various medical complexes on a body weight reduction, the main clinical manifestations and metabolic violations at patients with metabolic syndrome. Material and methods. There had been organized a clinical-functional examination and treatment of 80 patients with various manifestations of metabolic syndrome, aged from 25 to 55 years (39,1 years on the average) with prescription of a metabolic syndrome from 2 to 5 years. Result. Medical complexes with application of physical factors are developed and approved, the efficiency was estimated on indicators of a lipid range (triglycerides, the general cholesterol, lipoproteids of low and high density, (3-proteids and aterogenecity coefficient), and also to level of a glycemia, alanin and asparagin transaminases, creati-nine and urea — to define an extent of violation of metabolic processes. Conclusion. The most expressed results on a reduction of body weight, correction of the main clinical manifestations, metabolic violations and lipid imbalance were received at application of a diet, electrostatic massage from the device "Hivamat", multifactorial polymodal hardware influence from the AlfaLedOxyLight-Spa installation, complex influence on the musculoskeletal device from the Hyuber installation and psychological correction from Shufrid system.

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Renal dysfunction and state of metabolic and hemodynamic factors in patients with arterial hypertension

Year: 2011, volume 7 Issue: №4 Pages: 837-842
Heading: Internal Diseases Article type: Original article
Authors: Kurkina T.V., Bogoslovskaya S.I., Svistunov А.А., Kodochigova A.L, Glybochko G.Kh., Klochkov V.A.
Organization: Saratov State Medical University, Saratov Regional Hospital for Veterans of Wars, Saratov Institute of Cardiology, Russia, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

The aim of the investigation is to carry out comparative evaluation of metabolic and hemodynamic indices in patients with arterial hypertension (AH) and renal dysfunction; to study the interrelation between arterial blood pressure level normalization and the presence or lack of microalbuminuria (MAU) in the morning urine portion of patients with AH after therapy with antihypertensive preparations (APs) of various groups. Methods. 121 persons have been investigated, 91 out — patients of both sexes, aged 33-55, with the diagnosis of arterial hypertension of stage II risk III, who have been taking Perindopril, Telmisartan and Bisoprolol for3 months. The control of arterial pressure level, biochemical analysis of metabolic indices and morning urine portion test for microalbuminuria has been carried out. Results. MAU has been revealed in 17,6% patients, occurring more frequently in men than in women. Microalbuminuria is accompanied by reliable decrease of total and ionized calcium and magnesium concentrations, an increase of potassium level in blood plasma, increase of cholesterol, triglycerides, glucose and levels. Patients with AH and renal dysfunction reliably demonstrate higher levels of systolic and diastolic arterial pressure in the morning and evening hours, their normalization effect after APs intake is significantly interconnected with MAU presence. Conclusion. In patients with AH and MAU the main risk factors of cardio-vascular diseases development are more expressed. Microalbuminuria is a risk factor in patients with arterial hypertension and may influence on the basic blood electrolyte balance. While carrying out antihypertensive therapy the presence of MAU should be taken into consideration

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Investigation Of Arterial Blood Pressure Level And Metabolic Indices In Patients With Arterial Hypertension At Pharmacotherapy With Antihypertensive Medicines Of Various Chemical Structure

Year: 2009, volume 5 Issue: №4 Pages: 500-505
Heading: Clinical Pharmacology Article type: Original article
Authors: T.V. Kurkina, A.A. Svistunov, S.I. Bogoslovskaya, V.A. Klochkov, E.V. Luchinina, G.Kh. Glybochko
Organization: Saratov Institute of Cardiology, Russia, Saratov State Medical University
Summary:

The research goal is to carry on the comparative analysis of medicines of various chemical structure, Telmisar-tan and Bisoprolol, and to reveal their effect on the arterial blood pressure level and the indices of various metabolic processes in patients with arterial hypertension. 60 out-patients with arterial hypertension (stage II risk III) both males and females aged 33-55 have been under study taking Telmisartan and Bisoprolol for 3 months. While treating the patients the arterial blood pressure level control and biochemical investigations for determination the indices of metabolic processes have been carried out. The investigated medications have provided the decrease of systolic and diastolic arterial pressure parameters, the increase of concentration of total and ionized calcium, chlorine ions, urea and total bilirubin in blood plasma. Therapy with Telmisartan has shown more significant increase of potassium level in erythro-cytes, decrease of levels of natrium, glucose, glycolized hemoglobin and triglycerides and increased contents of alani-naminotransferase and aspartataminotransferase. The course of therapy with Bisoprolol has restored the normal level of magnesium in blood plasma, has not have any influence on carbohydrate and lipid metabolism, increased the level of alaninaminotransferase and significantly increased the contents of total and ionized calcium, urea and creatinine. 3-months therapy with Telmisartan and Bisoprolol has proved the decrease of systolic and diastolic arterial pressure in patients with arterial hypertension. The medications under study have had active and variable effects on metabolic indices

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