Saratov JOURNAL of Medical and Scientific Research

Chlamydia trachomatis

Problems and ways to improve the laboratory diagnosis of chlamydial infection

Summary:

The review highlights the historical aspects and modern concepts of laboratory diagnosis of chlamydial infection. The studies on investigation of different strains of Chlamydia trachomatis performed in Russian Federation and abroad are summarized. The results of research of domestic and foreign scientists aimed at finding the perfect laboratory test for identification of C. trachomatis on the basis of molecular biological methods are analyzed and presented.

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Detection of Chlamydia trachomatis in blood samples as a diagnostic method for complicated and persistent forms of urogenital chlamydia infections

Summary:

Goal: the study of the effectiveness of the method for laboratory diagnostics of urogenital chlamydial infection in patients with chronic form of the disease. Material and methods. The presence of DNAof C. trachomatis was detected by PCR in either genital or extragenital (blood) sites in eighth patients (four men and four women). Results. It is established that in biological material taken from extragenital (blood) sites, C. trachomatis was detected in all patients examined (in 100% of cases), while in clinical samples obtained from genital sites, in seven patients only (87.5%). Conclusion. We found that specific chlamydial DNAcan be detected in extragenital (blood) site, despite the negative reaction in the clinical material from the genital tract of patients with genital chlamydial infection.

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THE EFFECTIVE TREATMENT OF UROGENITAL CLAMIDIOSIS

Year: 2006, volume 2 Issue: №4 Pages: 40-43
Heading: Urology Article type: Original article
Authors: Skripkin Yu.K., Dvornikov A.D., Skripkina P.A.
Organization: Russian State Medical University
Summary:

Infection of genito-urinary tract, caused by C. trachomatis are common worldwide and especially among childbearing age individuals. This infection is the most prevalent sexually transmitted bacterial infection and can cause considerable reproductive morbidity in women. The peculiarity of this infection to others is asymptomatic course and inclination to chronic inflammation and fibrotic disease of the urogenital tract. Based on a contemporary literature review, research work and own experience, the authors present data on the epidemiology, clinical picture and treatment of Chlamydia trachomatis urogenital infecnions.

THE EFFECTIVE TREATMENT OF UROGENITAL CLAMIDIOSIS

Year: 2006, volume 2 Issue: №3 Pages: 73-76
Heading: Urology Article type: Original article
Authors: Yu.K. Skripkin, A.S. Dvornikov, P.A. Skripkina
Organization: Russian State Medical University
Summary:

Infection of genitor-urinary tract, caused by C. trachomatis are common worldwide and especially among childbearing age individuals. This infection is the most prevalent sexually transmitted bacterial infection and can cause considerable reproductive morbidity in women. The peculiarity of this infection to others is asymptomatic course and inclination to chronic inflammation and fibrotic disease of the urogenital tract. Based on a contemporary literature review, research work and own experience, the authors present data on the epidemiology, clinical picture and treatment of Chlamydia trachomatis urogenital infections.