Saratov JOURNAL of Medical and Scientific Research

Orenburg State Medical University

Effectiveness of neure-protective therapy in patients with glaucoma

Year: 2018, volume 14 Issue: №4 Pages: 828-831
Heading: Ophtalmology Article type: Case report
Authors: Aprelev А.Е., Barbos Yu.A., Mukhanko I.Zh., Cherednichenko N.L., Abdulgazizova Z.F., Kataganova A.A., Bernovskaya A.A.
Organization: Mineralovodsky district hospital, Orenburg Regional Clinical Hospital, Orenburg State Medical University, Regional Clinical Diagnostic Center in Stavropol City, Stavropol Regional Clinical Hospital, Stavropol State Medical University

The results of clinical evaluation of three patients who were included in the multicenter study of the
effectiveness of neuroprotective treatment and its impact on the quality of life of patients with POAG are
presented in the article. Dynamics of visual acuity, intraocular pressure, total visual fields, photostress
test, contrast sensitivity and quality of life (according to the NEIVFQ-25 questionnaire) in patients
treated with neuroprotective study drug with 10 intramuscular injections administered 5mg once a day
are presented. Data on the improvement of visual functions and quality of life in patients with Stage I, II
and III of POAG who had undergone treatment with the study drug are demonstrated.

Keywords: quality of life
2018_4-2_828-831.pdf261.13 KB

Adaptation to periodic pressure chamber hypoxia and its influence on systolic and diastolic functions in chronic heart failure

Year: 2012, volume 8 Issue: №2 Pages: 247-251
Heading: Internal Diseases Article type: Original article
Authors: Dmitrieva М.К.
Organization: Orenburg State Medical University

Research objective is to determine the influence of adaptation method to periodic pressure chamber hypoxia on dynamics of systolic and diastolic functions of myocardium in patients with early stages of chronic heart failure. Materials and Methods: 100 men with post-infarction cardiosclerosis at the age of 40-65 years with I and IIA stages and l-ll functional classes (NYHA) of chronic heart failure have been examined. Results: Positive dynamics of systolic and diastolic cardiac functions and other parameters of echocardioscopy under the influence of the hypoxic therapy in comparison with classical physical rehabilitation have been obtained. Furthermore, a more significant effect has been observed in patients with CHF IIA. Conclusion: Improvement in the geometry of the heart has proved that adaptation method to periodic pressure chamber hypoxia could be recommended for rehabilitation of patients with heart failure of early stages.

201202_247-251.pdf264.89 KB

Features of neurological and neuropsychological changes in the initial stages of encephalopathy in patients with idiopathic epilepsy

Year: 2011, volume 7 Issue: №4 Pages: 870-874
Heading: Neurology Article type: Original article
Authors: Burdakov V.V. Gumalatova N.V.
Organization: Orenburg State Medical University, Municipal health clinic Municipal Clinical Hospital № 3, Orenburg

Aim. The study was undertaken to identify the features of neurological and cognitive changes in idiopathic epilepsy based on neurological and neuropsychological research. Methods. A total of 105 patients with idiopathic epilepsy at the age of 16 to 45 years. In orderto identify features neuropsychological disturbances, all patients were systematized by the nature and frequency of seizures. Results. As a result of the work identified major the nature neurological and neuropsychological symptoms and syndromes of primary stages of encephalopathy in patients with idiopathic epilepsy

201104_870-874.pdf328.82 KB


Year: 2007, volume 3 Issue: №4 Pages: 133-137
Heading: Surgery Article type: Original article
Authors: A.M. Gurianov
Organization: Orenburg State Medical University

Prophylaxis of infection in the case of burns includes a number of surgical and antiepidemic precautions, including the use of antibiotics. Unfortunately, antibiotics are often causing allergic reactions, dysbacteriosis and contribute to appearance of antibiotic resistant strains of microorganisms. In this article the results of treating of 190 patients with thermal burns are described. In order to prevent pyoinflammatory complications, 100 patients from the total of 190 ones were given the medicine “Sporobacterin fluidum” and 90 patints of the same 190 ones were given antibiotics. The medical effect of “Sporobacterin fluidum” is based on translocation of Bacillus subtilis from the bowels into the wound when they produce antibiotics, enzymes, immunomodulator.
It is found out that derangements, which appear after burns lead to dysfunction of all organs and systems, buildup of intoxication and change of the composition of biocenose of intestines. The research results prove that “Sporobacterin fluidum” is an effective medicine for prophylaxis of infectious complications and contributed to correction of biocenose of intestines, reduction intoxication and cutting down the period of wound healing and period of in-patient treatment of burnt.


Year: 2007, volume 3 Issue: №4 Pages: 93-98
Heading: Traumatology and Orthopedics Article type: Original article
Authors: D.V. Alimov, A.A. Safronov, M.B. Litvak, S.A. Nemolyaev, H.M.F. Sakalla
Organization: Orenburg State Medical University

The scientific research deals with the application of probiotic “Sporpbacterin liquid” as method for preventive treatment of the infectious complications using the method of transosseous osteosyntesis.