Saratov JOURNAL of Medical and Scientific Research

Russian State Medical University

Comparison of the efcacy and safety of the elaborated combined laser technology and «grid» laser photocoagulation in patients with the initial stages of the idiopathic epiretinal membrane

Year: 2019, volume 15 Issue: №2 Pages: 546-550
Heading: Ophtalmology Article type: Original article
Authors: Takhchidi K.P., Kachalina G.F., Kasmynina T.A., Tebina E.P.
Organization: Russian State Medical University
Summary:

Purpose: to evaluate the efectiveness and safety of the developed combined laser technology in comparison with «grid» laser photocoagulation in the treatment of patients with the initial stages of the idiopathic epiretinal membrane. Material and Methods. The analysis of two groups of patients was carried out. The frst group (32 patients (32 eyes)) was treated using the developed combined laser technology; the second group (30 patients (30 eyes)) was treated using grid» laser photocoagulation. The assessment uncorrected visual acuity, best corrected visual acuity, central retinal thickness and central retinal sensitivity was performed. The maximum follow-up is 5 years. Results. In the frst group of patients the maximum visual-functional results (UCVA, BCVA, CRS) were obtained from 3 to 12 months, followed by their stabilization until the end of the observation period. The CRT gradually decreasedduring all observation period. In the second group of patients a short-term positive efect was achieved up to 3 months of observation with an increase UCVA, BCVA, CRS. 12 months post op there was increasing of CRT with decreasing UCVA, BCVA, and CRS until the end of study. Conclusion. The technology of combined laser treatment showed high efciency in comparison with «grid» laser photocoagulation with stabilization / increase of UCVA, BCVA, CRS and stabilization / improvement of the morphological parameters of the retina — the decrease of CRT.

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Endothelial dysfunction in burn injury

Year: 2019, volume 15 Issue: №2 Pages: 377-379
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Morrison V.V., Bozhedomov A.Yu., Morrison A.V.
Organization: Russian State Medical University, Saratov State Medical University
Summary:

Objective: to estimate the level of markers of endothelial dysfunction in burn injury of various severities. Material and Methods. 57 patients were included in the study. The level of vascular endothelial growth factor (VEGF), endothe-lin, nitric oxide metabolites (NO), and the amount of circulating desquamated endothelial cells were determined in the dynamics of burn injury development. Results. In burn injury there was an increased amount of endothelial dysfunction markers in blood, which is highly expressed on the 7-15th day. Moreover on the 7th day in case of severe and extremely severe burn injury the level of VEGF was increased over 50 times while the amount of endothelin, nitric oxide metabolites and circulating desquamated endothelial cells becomes higher in 3–5 times. Conclusion. The research outcomes have proved the damage of endothelial lining in burn injury.

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Academic D.K. Zabolotny and his contribution to the development of medical science (to the 150th birth anniversary)

Summary:

The article presents biographical data of academician D. K. Zabolotny and his scientific and practical contribution to the fight against plague and cholera, to the research of germ and pathogenesis of syphilis and to the management of preventative disinfection department in Russia.

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Professor J.J. Plenk — founder of world scientific dermatology.

Year: 2016, volume 12 Issue: №3 Pages: 493-495
Heading: Dermatovenerology Article type: Author's opinion
Authors: Betechtin M.S., Zavyalov A.l.
Organization: Saratov State Medical University, Russian State Medical University
Summary:

The article presents the biography of Professor J. J. Plenck and his scientific and practical contribution to the development of European clinical medicine in the second half of the 18th century and in the establishment of world scientific dermatology.

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National calendar of preventive vaccination: problems, solutions and results in Saratov region

Year: 2013, volume 9 Issue: №2 Pages: 192-196
Heading: Infectious Diseases Article type: Review
Authors: Uchaikin V.F., Shamsheva O.V., Mikhailova ЕМ., Shvedova N.M
Organization: Saratov State Medical University, Russian State Medical University
Summary:

National immunization calendar of Russia includes 11 entities that are carried out against the mass vaccination of children. And at the present time there is a high incidence of tuberculosis, whooping cough, measles incidence is increasing. In the article the causes have been analyzed, some possible solutions have been drawn.

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Study of nerve fibers nature reinforcing duodenal contractions by electrical stimulation of sympathetic nerve

Year: 2011, volume 7 Issue: №3 Pages: 580-583
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Sveshnikov D.S., Kirichuk V.F., Smirnov V.M., Myasnikov I. L, Kuchuk A.M., Trofimova J.E., Trubetskaya M.A.
Organization: Saratov State Medical University, Russian State Medical University
Summary:

The subject of the article is to investigate the mechanism of increased reactions by electrical stimulation of the sympathetic nerve. Materials and methods: Experiments on dogs have shown that stimulant reactions during blockade of a-adrenergic by phentolamine and (3-adrenergic receptors with propranolol were completely eliminated by lizer-gol —the blocker of 5-HT12-receptors. Results: Infusion of lizergol did not influence on duodenal motor activity and the function of the vagus nerve. Conclusion: Effector neuron is found out to be serotonergic and its action is provided by 5-HT1 2 receptors

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Differentiated method of physiotherapy for patients with congenital hip dislocation in postoperative rehabilitation period

Year: 2011, volume 7 Issue: №2 Pages: 505-510
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Pozdniakova О.N., Kiselev D.A, Laisheva О.A., Gubanov V.V.
Organization: Russian State Medical University
Summary:

The aim of the research was to develop a new rehabilitation method for patients with congenital dislocation of hip in the late postoperative period. It is based on anatomical, physiological, pathogenetic, functional and ontogenetic foundations and prevents coxarthrosis development and progress. Materials. The data from examination and treatment of 71 patients are presented. The main group consisted of 48 children and the comparison group consisted of 23 children. Methods. Data processing was made by «Statistica 6,0» programme. Normalcy of distribution was estimated by the Shapiro-Wilktest. Hypothesis proof of two means equality was provided by the Wilcoxon signed-ranktest. Correlation analysis was made by definition of the Pearson correlation coefficient and the Spearman»s rank correlation coefficient. Rate difference was considered as a reliable rate if p

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Study of sympathetic trunk fibers nature for cause determination of increase of stomach contractions

Year: 2010, volume 6 Issue: №2 Pages: 392-395
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Smirnov V.М., Sveshnikov D.S., Kirich и к V.F., Myasnikov I. L, Kuchuk A.V.
Organization: Saratov State Medical University, Russian State Medical University
Summary:

The investigation has revealed that stimulation of sympathetic nerve in the thoracic cavity in dogs provides no inhibition but increase in stomach contractions in most cases. This effect is raised with the blockage of a-and (3-adrenergic receptors and it is removed by blockage of 5-HT12-receptors. It has been stated that there are serotonergic fibers that increase stomach contractility

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Efficacy evaluation of functional motor regulation method with mathematical analysis of EEG

Year: 2011, volume 7 Issue: №1 Pages: 039-044
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Balabanova V.A., Kiselev D.A., Laisheva О.А., Gubanov V.V.
Organization: Saratov State Medical University, Russian State Medical University, Moscow Children Clinical Hospital
Summary:

Effects of functional motor regulation method have been measured using the spectral and coherent EEG. Obtained results have fully confirmed the hypothesis that the clinical effectiveness of the method is associated with the formation of new regulatory links in the CNS with inclusion of such deep structures as the limbic and diencephalic systems

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Clinical features of nonspecific ulcerative colitis and Crohn's disease in children

Year: 2010, volume 6 Issue: №3 Pages: 650-653
Heading: Pediatrics Article type: Original article
Authors: Malakhinova N.A.
Organization: Russian State Medical University
Summary:

The article presents the data of age, manifestation, localization and clinical features of course of Crohn's disease and nonspecific ulcerative colitis. A total of 85 children with Crohn's disease and 101 children with nonspecific ulcerative colitis have been under study

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