Saratov JOURNAL of Medical and Scientific Research

Lim V.G.

Saratov State Medical University, Department of Narcology-Psychiatry and Traditional Medicine of Raising Skills Faculty, Assistant Professor, Doctor of Medical Science

Pharmacopuncture in complex treatment of alcoholic polyneuropathy

Year: 2012, volume 8 Issue: №1 Pages: 085-088
Heading: Neurology Article type: Original article
Authors: Beloglazov D.N., Lim V.G.
Organization: Saratov State Medical University, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

Treatment alcoholic polyneuropathy is one of the most important challenges of health care not only in Russia, but throughout the world. Material and methods. A comparison study of efficacy and tolerability ofthefarmacopuncture in 58 patients with alcoholic polyneuropathy [36 (62,1%) male, 22 (37,9%) female, mean age 41,5±12,4 years]. Introduction of thiamin (vitamin B1) in BAP of the cohort studied was accompanied by a positive dynamics of both subjective and objective clinical symptoms. By means of standard ENMG methods the study was made of motor fibrae of median, tibia, fibular and sensory fibrae of median nerves. Results. Farmacopuncture is tolerable and safe. Conclusions. The results of the study confirm an assumption of introduction of thiamin in БАТ efficacy in alcoholic polyneuropathy and allow to recommend the drug for a wide clinical application.

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Pathogenetic aspects of alcoholic encephalopathy treatment

Year: 2010, volume 6 Issue: №4 Pages: 796-799
Heading: Narcology Article type: Review
Authors: Shchetinin S.G., Barylnik Yu.B., Lim V.G.
Organization: Saratov State Medical University
Summary:

Alcohol is considered to be the most common exogenous toxins, causing encephalopathy. The defeat of almost all parts of the nervous system should be assigned to the special features of ethanol. Neurophysiological mechanisms of development of substance dependence are based in the stem and limbic structures of the brain that are involved in ensuring the regulation of emotional state, mood, motivation sphere, psychophysical tone of human behavior in general and its adaptation to the environment. Stress or disruption of the normal functioning of these structures can lead to the formation of abstinence syndrome, affective disorders in remission and craving for alcohol. Dopaminergic and opioid (endorphin) system play an important role in the genesis of various mental and motor disorders. In some way alcohol dependence can be regarded as an endorfinodefitsitnoe disease with a pathogenetic point of view. Activating of opioidereal system by trans-cranial electrical stimulation promotes the restoration of disturbed emotional, cognitive and autonomic functions, reduces craving for alcohol and in that way increases the effectiveness of rehabilitation treatment

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Transcranial electrostimulation in patients with alcoholic encephalopathy

Year: 2010, volume 6 Issue: №3 Pages: 625-628
Heading: Neurology Article type: Original article
Authors: Barylnik Yu.B., Lim V.G., Shchetinin S.G.
Organization: Saratov State Medical University
Summary:

The method of transcranial electrostimulation (TES) was used for treating patients with alcoholic encephalopathy against the background of the basic treatment, which includes nootropics, normotimics, soporifics, over-all strengthening therapy and other devices. The course of treatment consisted of 10 daily procedures lasting for 30 minutes. The TES influence was evaluated according to the clinical state, the neurologic status, including EEG (electroencephalogram), the psychometric scales were also used for evaluating the manifestation of depression, anxiety and working memory in comparison with appropriate indices in the control group of patients, who were being treated by the traditional method. TES led to normalization of health state, neurologic status and vegetative innervation, the reduction in pathologic inclination, which corresponded to general improvement of the state of patients, EEG indices and psychometric scales

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Rating system in evaluation of departments and teaching staff and its use in management of basic processes of quality of education at medical university

Year: 2010, volume 6 Issue: №2 Pages: 472-474
Heading: Pedagogics and Education Article type: Original article
Authors: A.A. Protopopov, V.G. Lim, Yu.V. Chernenkov, Yu.M. Spivakovsky
Organization: Saratov State Medical University
Summary:

The article presents the experience of departments and teaching staff rating at Saratov Medical University. Rating evaluation was carried out according to the criteria proposed by the staff and approved by the Quality and Rating Committee of the University. The rating evaluation is a type of quantitative and qualitative monitoring of teachers' activities and departments, which can be combined with other evaluating methods used in high schools

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Change in function of thl - and th2-lymphocytes and cytokine profile at chronic intoxication of ethanol

Year: 2010, volume 6 Issue: №2 Pages: 307-309
Heading: Anaesthesiology and Reanimatology Article type: Original article
Authors: A.A. Svistunov, P.F. Zabrodsky V.G. Lim, V.A. Grishin
Organization: Saratov State Medical University
Summary:

It has been established during the experiments carried on noninbred rats that chronic intoxication of ethanol (30 days, total dose - 6,0 LD50) essentially reduces concentration of cytokines (IFNy, IL-2, IL-4, IL-6,IL-10) in blood, reduces interrelation of IFNy/IL-4 in comparison with the control, suppresses immune reactions, indicating the greater lesion of Th1-cells in comparison with Th2-lymphocytes

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Alcoholic polyneuropathy

Year: 2010, volume 6 Issue: №1 Pages: 117-120
Heading: Neurology Article type: Review
Authors: D.N. Beloglazov, V.G. Lim, A.A. Svistunov
Organization: Saratov State Medical University
Summary:

Alcoholic polyneuropathy is one of the most important challenges of health care not only in Russia, but throughout the world. The problems concerning pathogenesis, clinical manifestations, diagnosis and treatment of the above clinical form of alcoholic polyneuropathy are discussed

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Activation of р-450-depended monooxygenases changing immunotoxicity of phosphoroorganic compounds due to their metabolism character

Year: 2010, volume 6 Issue: №1 Pages: 046-048
Heading: Physiology and Pathophysiology Article type: Original article
Authors: P.F. Zabrodsky, V.F. Kirichuk, V.G. Lim, I.Kh. Yafarova
Organization: Saratov State Medical University, Saratov Military Institute of Biological and Chemical Safety
Summary:

It was established that the application of the monooxygenase system inductors (MSI) of phenobarbital and benzonal up to acute poisoning of animals by trichlorfom in a dose of 1,0 LD50, metabolized in the organism till production of compounds with higher toxicity caused its immunotoxic properties increase. The experiment was carried out on outbred white rats. the acute dimethyldichlorvinylphosphate (1,0 LD50) poisoning, biotransformation of which proceeded with formation of less-toxic and non-toxic compounds after MSI introduction, caused its decrease of suppression influence on immunity system indices

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Realisation Experience And Monitoring Perspectives In The Educational Sphere At Saratov State Medical University

Year: 2009, volume 5 Issue: №4 Pages: 635-638
Heading: Pedagogics and Education Article type: Original article
Authors: А.А. Svistunov, V.G. Lim, Yu.V. Chernenkov, E.S. Koznova
Organization: Saratov State Medical University
Summary:

A great experience of various research instruments in the context of new complex of techniques on collecting and feedback interpretation between various subjects of educational process has been received. Realization experience has been generalized, analyzed and presented in the article

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EFFICACY OF OSTHEOREFLEXOTHERAPY IN THE TREATMENT OF NEUROLOGICAL DISORDERS OF LUMBAR OSTHEOCHONDROSIS

Year: 2008, volume 4 Issue: №2 Pages: 137-140
Heading: Stomatology Article type: Original article
Authors: D.N. Beloglazov, V.G. Lim, D.M. Puchinyan, A.A. Svistunov, V.G. Ninel
Organization: Saratov State Medical University, Saratov Scientific Research Institute of Traumatology and Orthopedics, Saratov Regional Children Clinical Hospital
Summary:

The article gives information about efficacy of osteoreflexotherapy in the treatment of patient with lumbar spine ostheochondrosis. Combination of ostheoreflexotherapywith introduction of homotoxic drug into reflexogenous zones of vertebral spinous processes ofL4-S1 vertebrae makes it possible after 10 seances to stop the pain in lumbosacral region, to restore superficial sensitivity, tendon reflexes.

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