Midlenko V.I.

The research goal was to estimate efficiency of medicine phosphogliv by the directed administration in complex therapy for patients with biliary pancreatitis and НСV- infection. 62 patients with biliary pancreatitis and НСV-infection were examined. These patients were divided into 2 comparable groups: control group I (50 persons) and basic group II (12 persons). In group I traditional basic therapy of biliary pancreatitis was carried out with injection of phosphogliv intravenously. Patients of group II were given erythrocytes intravenously with average therapeutic dose of phosphogliv. Introduction of medicines in autologous erythrocytes was performed by hypotonic lysis.
Effective influence of directed administration of preparation phosphogliv demonstrated decrease in level of bilirubin in blood, activity of AlAt, AsAt in patients of research group. Side-effects were not revealed.
In conclusion the investigation proved that more effective influence of phosphogliv on level of bilirubin in blood and activity of AlAt, AsAt can be reached in combination with traditional basic therapy.

468 patients aged 14 to 88 years underwent surgery concerning perforative ulcer os stomach and duodenum. 10 patients had symptoms of stenosis including 10 patients with penetration. It is demonstrated that incision of ulcer with duodenoplasty or pyloduodenoplasty permit to treat successfully perforative ulcers and to achieve good functional results.

The analysis of the treatment results of 319 patients with complicated forms of gastroduodenal ulcer disease has been carried out. The group is formed by the 223 patients over 60 years old and 96 young and middle-aged patients. The description ofpreoperative and postoperative treatmentwith application of the controlled sympathetic medication denervation of the elderly and aged people with complicated forms of gastroduodenal ulcer disease in the preoperative period and the exposure of the abdominal nerve plexus to alternative magnetic field of “Magniter" device have been provided. . The treatment algorithm of elderly and aged people with such pathology has been introduced. The results of the research have revealed reliable decrease in postoperative complications development incidence, postoperative complication development relief, earlier improvement of the clinical, laboratory and instrumental indices in elderly and aged patients with complicated forms of gastroduodenal ulcer disease, and also postoperative mortality decrease and cuts of the patients' stay period in hospital.