Saratov JOURNAL of Medical and Scientific Research

Krishtopenko S.V.

Deputy Director of Gastroenterological Centre of Volga Region Federal District of the Russian Federation, Nizhni Novgorod, Doctor of Medical Science, Professor

CROHN’S DISEASE DIAGNOSTICS IN ACUTE STAGE WITH THE USE OF HIGHLY EFFECTIVE LIQUID CHROMATOGRAPHY BLOOD SERUM

Summary:

15 patients with the endoscopically and morphologically verified diagnosis of the Crohn’s disease and 14 healthy humans at the age of 23- 24 years have been examined. The Crohn’s disease index activity was 235 - 310 units. The possibility highly effective liquid chromatography blood serum use for diagnosis of the disease has been studied. A blood serum dried extract has been investigated on the "Milichrome A 02" chromatograph (Novosibirsk, "Econova "joint-stock company). The chromatograms have been treated with the use of a multilevel cluster analysis with a pathologic three-measured state form, differing from a healthy human. A diagnostic sensitivity and accuracy of the method has achieved 100%.

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