Saratov JOURNAL of Medical and Scientific Research

Yudina G.K.

Saratov State Medical University n.a. V. I. Razumovsky, Associate Professor of Department of Neurology n.a. K.N. Tretiakoff, PhD

Clinical case of the manifestation of Parkinson's disease in a patient with neuro-leptic-induced parkinsonism

Year: 2019, volume 15 Issue: №1 Pages: 199-202
Heading: Neurology Article type: Case report
Authors: Yudina V.V., Makarov N.S., Yudina G.K.
Organization: Saratov State Medical University
Summary:

The article presents data on the mechanisms of development of drug-induced parkinsonism in patients taking neu-roleptic drugs, as well as on specifics of the development of Parkinson's disease in these patients. A clinical case of Parkinson's disease development in a patient with drug-induced parkinsonism who has been taken antipsychotics for a long time is described.

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Konstantin Nikolaevitch Tretiakoff: some of the biography pages (the 125th anniversary of the birth)

Year: 2017, volume 13 Issue: №1 Pages: 123-127
Heading: Neurology Article type: Short message
Authors: Kolokolov O.V., Razdorskaya V.V., Yudina G.K.
Organization: Saratov State Medical University
Summary:

Konstantin Tretiakov is one of the founders of Neurological science schools in Sao Paulo (Brazil) and in Saratov. Carrying out the analysis of the materials of the State archive of Saratov, the Russian State Library, the Russian National Library, the library of Saratov Medical University, Internet resources. The information about the K.N. Tretiakov's life, career and scientific work Tretiakov is presented.

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Parkinson's disease in Russia: prevalence and incidence

Year: 2016, volume 12 Issue: №3 Pages: 379-384
Heading: Neurology Article type: Review
Authors: Razdorskaya V.V., Voskresenskaya O.N., Yudina G.K.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The results of the regional studies on the frequency of Parkinson's disease (PD) and the incidence of it in Russia have been generalized, the main factors that determine the quality of the estimates of this disease epidemiological indicators have been identifyd. The article summarizes data from 19 original studies on the epidemiology of parkinsonism and Parkinson's disease in Russia published between 2005-2015. Due to the statistical heterogeneity of the primary results computational analytics was not applied to the data; however, data consolidation allowed to perform a trend analysis of epidemiological indicators. The methodological basis of the majority of studies was medical aid appealabil-ity; two of the studies used door-to-door surveys. One of the studies returned questionably low epidemiological indicators obtained from the medical records, and the rest showed the standardized prevalence of 30.0-139.9/100,000 and incidence of 7.63-21.8/100,000 per year. Contribution of Parkinson's disease to the nosological structure of parkinsonism was >61.3%. Estimate of the number of patients with PD in Russia is approximately 210,000 people. Conclusions are made regarding the prevalence of PD in Russia according to the cross-cutting research on the level of indicators in the Western countries. The prevalence of PD by appealability is 2-3 times less than the prevalence in continuous research, both national and foreign. The incidence of PD, demonstrated in half of the studies, is stable from region to region and is comparable with the universally recognized values.

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Parkinsonism accompanying the left frontal lobe tumor

Year: 2016, volume 12 Issue: №2 Pages: 285-287
Heading: Neurology Article type: Case report
Authors: Razdorskaya V.V., Kolokolov O.V., Lomakin A.l., Yudina G.K.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University
Summary:

Objective: to draw the attention of experts on rare cause of secondary parkinsonism — a brain tumor. Material and methods. The clinical observation of the patient 52 years with Parkinson's syndrome. Brain MRI. Results. In parallel the patient had classical progressing clinic bilateral parkinsonism in combination with progressive cognitive decline. MRI research revealed the left frontal lobe tumor. Conclusions. Secondary parkinsonism as a result of intracerebral neoplasms are caused mostly by compression of basal ganglia or mesencephalon increasing tumors. Hemiparkinsonism in these cases usually precedes the other focal neurological symptoms.

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The diagnostic reliability of outpatient neurological care to patients with Parkinson’s disease

Year: 2012, volume 8 Issue: №2 Pages: 513-517
Heading: Neurology Article type: Original article
Authors: Razdorskaya V.V., Voskresenskaya O.N., Yudina G.K.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

Goal: discussion of the revealing aspects of Parkinson’s disease (PD) by ambulatory neurologists. Techniques: a longitudinal epidemiological survey on applications to a specialized clinic. Results. 603 patients with Parkinsonism suspicions were examined for a four-year period. The syndromal diagnosis of Parkinsonism/extra pyramidal syndrome was correctly recognized by ambulatory neurologists in ca. ¾ of the whole contingent of patients. Hypodiagnostics of PD was the most frequent mistake (71 of 146 corrected diagnoses). Hyperdiagnostics of PD followed by frequency (57 of 146 corrected diagnoses). Every ffth patient applied for consultation caused diffculties in the ambulatory chain. Conclusion. The diagnostic mistakes, no provisional diagnosis for every tenth PD patient cause justifed anxiety in the patients regarding the quality of guaranteed medical aid and force them to apply for specialized consulting reception individually.

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Diagnostics and treatment of vascular parkinsonism

Year: 2010, volume 6 Issue: №1 Pages: 120-123
Heading: Neurology Article type: Review
Authors: V.V. Yudina, O.N. Voskresenskaya, G.K. Yudina
Organization: Saratov State Medical University
Summary:

The article presents clinical syndromic classification of parkinsonism in relation to etiological factors. It also studies epidemiologic and historical aspects of vascular parkinsonism. the research work demonstrates clinical patterns, clinical pathologico-morphological criteria and clinical neurovisualizing correlations of postinsult and noninsult variants of vascular parkinsonism. the principles of basic and symptomatic treatment of vascular parkinsonism are considered. the observation of patients suffering from postinsult and noninsult variants of vascular parkinsonism have been carried out

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Ninetieth Anniversary of Parkinson’s Disease «Substantia Nigra» Theory

Year: 2009, volume 5 Issue: №2 Pages: 279-282
Heading: History of Medicine. Anniversary Dates Article type: Review
Authors: V.V. Yudina, N.S. Makarov, G.K. Yudina, L.A. Kabanova, O.N. Voskresenskaya
Organization: Saratov State Medical University
Summary:

Article is devoted to the Ninetieth Anniversary of Creation of the «substantia nigra» theory of Parkinson’s disease by famous Saratov scientist K. N. Tretjakov.

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