Saratov JOURNAL of Medical and Scientific Research

Zagidullina A.Sh.

Bashkir State Medical University, Associate Professor of Department of Ophthalmology with the Course of Institute of Additional Professional Education, PhD.

Comorbidity of diseases of the cardiovascular system and primary open-angle glaucoma

Year: 2018, volume 14 Issue: №4 Pages: 949-953
Heading: Ophtalmology Article type: Review
Authors: Zagidullina A.Sh., Latypova Е.А., Nugmanova A.R.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

This literature review examines the potential diagnostic contribution of syndromes and cardiovascular diseases: hypertension, atherosclerosis, vascular dystonia, and cerebrovascular pathology in the development of primary open-angle glaucoma (POAG). The study of relationships is relevant due to the commonality of some pathogenetic factors of POAG and these diseases and syndromes. It is necessary to take into account the effect of comorbid pathology in the early diagnosis of POAG, which will improve its quality, and the correction of associated disorders will contribute to the effectiveness of complex treatment of the disease.

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Central retinal vein thrombosis in a patient with newly diagnosed congenital thrombophilia

Year: 2018, volume 14 Issue: №4 Pages: 872-875
Heading: Ophtalmology Article type: Case report
Authors: Latypova E.A., Zagidullina A.Sh., Yamlikhanov A.G., Arslanova A.l., Nugmanova A.R.
Organization: Bashkir State Medical University of the Russian Health Care, City clinical hospital 10 Ufa
Summary:

To date the etiology and pathogenesis of retinal vein thrombosis have not been fully studied despite a large body of scientific research. The article describes a rare clinical case of central retinal vein thrombosis in a 52-year-old man with newly diagnosed congenital thrombophilia.

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Glaucoma incidence analysis and prognosis in adult population of Bashkortostan Republic

Year: 2018, volume 14 Issue: №4 Pages: 825-828
Heading: Ophtalmology Article type: Original article
Authors: Aznabaev В.М., Zagidullina A.Sh., Fakhretdinova E.V.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Purpose: to analyze the general and primary incidence of glaucoma in the adult population in the Republic of Bashkortostan over the 2010-2017 period; make a medium-term forecast for five years. Material and Methods. The analyzed data was based on official statistics of the Ministry of Health of the Russian Federation over the 2010-2017 period. The level of general and primary incidence per 100 thousand population was estimated; the five-year forecast for glaucoma incidence was simulated using mathematical modeling. Results. The Republic of Bashkortostan had the highest rate of general and primary glaucoma incidence in the adult population as compared with the incidence rate in the Russian Federation. The Republic of Bashkortostan ranks first in the absolute number of patient with glaucoma and fourth ranks in general incidence per 100 thousand comparing with Volga Federal District data. The level of general glaucoma incidence in the adult population increased by 23.0% over the 2010-2017 period and primary incidence — by 47.0%. The five-year simulated forecast predicts possible further growth of general and primary glaucoma incidence in the republic by 2022. Conclusion. The performed analysis and simulated forecast of general and primary glaucoma incidence for the adult population in the Republic of Bashkortostan show growth trends.

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Main markers of vascular endothelium dysfunction in primary open-angle glaucoma

Year: 2018, volume 14 Issue: №4 Pages: 820-824
Heading: Ophtalmology Article type: Review
Authors: Nugmanova A.R., Zagidullina A.Sh.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

The review presents current literature data on the functions of the vascular endothelium, its role in the pathogen-esis of vascular pathologies, as well as the main markers of its dysfunction. Vascular endothelium plays a role in the development of thrombosis, angiogenesis, remodeling of the vascular wall. It is involved in the regulation of vascular tone, local hemostasis, proliferation. The results of clinical studies of the endothelium capacity, which disorders may accompany primary open-angle glaucoma and contribute to the progression of glaucomatous optic neuropathy, are presented here.

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