Saratov JOURNAL of Medical and Scientific Research

Mukhamadeev T.R.

Bashkir State Medical University, Professor of Department of Ophthalmology with Postgraduate course, DSc; ZAO Optimedservis, Deputy General Director for Scientific and Clinical Work

Thermal imaging characteristics of ultrasonic and pneumatic guillotine 25 gauge vitrectors

Year: 2018, volume 14 Issue: №4 Pages: 916-919
Heading: Ophtalmology Article type: Original article
Authors: Aznabaev В.М., Dibaev T.N., Mukhamadeev T.R., Vafiev A.S., Shavaliev I.Kh.
Organization: Bashkir State Medical University of the Russian Health Care, ZAO Optimedservis
Summary:

Purpose: to analyze thermal characteristics of ultrasonic and pneumatic guillotine 25G vitrectors in the experiment. Materials and Methods. In vitro studies were performed using Testo 882 thermal imager under various conditions for a more complete assessment of thermal characteristics of 25G ultrasonic vitrector and 25G pneumatic guillotine vitrector. First experiment was carried out in normal saline solution of room temperature, second experiment was performed in air medium. Results. It was found that during operation of ultrasonic and pneumatic guillotine vitrectors, the temperature threshold of 45°C, which is critical for thermal damage to retinal tissue, was not reached in all experiments. Under severe conditions (working in the air medium without cooling of vitrector tip), different localization of the heating zone in ultrasonic (at proximal part of the needle) and pneumatic (at distal part, near the port) vitrectors was detected. Conclusion. In experimental conditions, the thermal safety of ultrasonic and pneumatic guillotine vitrectors of caliber 25G has been proved by the method of infrared thermal imaging.

AttachmentSize
2018_4-2_916-919.pdf716.51 KB

Autonomous device for registration of direct current potential of eye in experiment and clinic

Year: 2018, volume 14 Issue: №4 Pages: 910-913
Heading: Ophtalmology Article type: Author's opinion
Authors: Mukhamadeev T.R., Yamgutdinov R.R., Vafiev A.S., Kalmetyev A.Kh., Yamlikhanov A.G., Tumashinov V.N.
Organization: Bashkir State Medical University of the Russian Health Care, ZAO Optimedservis
Summary:

 The article presents an autonomous device for recording of direct current potential of eye at rest and at different illumination levels to assess the functional state of the photoreceptor— retinal pigment epithelium complex in experiments on laboratory animals and in clinical practice including vitreoretinal surgery.

AttachmentSize
2018_4-2_910-913_1.pdf532.15 KB

Light-induced total electrical activity of retina in models of particular disorders in vivo and in vitro

Year: 2018, volume 14 Issue: №4 Pages: 903-909
Heading: Ophtalmology Article type: Original article
Authors: Mukhamadeev T.R., Ahmadeev R.R.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Aim: to conduct an electrophysiological study of functional state of retina under the influence of ophthalmological surgical and typical pathogenic factors on various experimental models. Material and Methods. Experimental registration of electroretinogram (ERG) and total receptor potential (TRP) in vivo and in vitro under influence of various pathogenic factors. Results. It was shown that there is a slight decrease in the amplitude of the ERG in the early postoperative period after vitreoretinal surgery in rabbits followed by almost complete restoration of the electroretinogram to its original values. Registration of electrical activity of isolated retina of amphibians showed a rapid inhibition of a-, b- and d-waves of ERG during anoxia and their recovery during re-oxygenation. TRP inhibition during anoxia is developed more slowly than ERG inhibition, but its recovery does not occur during re-oxygenation. Preparations of isolated retinas with preserved pigment epithelium were much more resistant to oxygen deficiency. The results are discussed from a neurophysiological point of view and are consistent with the paradigm of retinal remodeling in experimental pathology with the leading role of neural mechanisms. Conclusion. The most adequate and effective methodological approach to assess the impact of typical and specific pathogenetic factors on the overall functional state of the retina is to register the total electrical activity of the retina in models in vivo. Studies of more subtle changes at the receptor, neuronal and interneuronal levels under the influence of various extreme factors on the retina are more expedient to carry out on in vitro models with registration of both total and local activity.

AttachmentSize
2018_4-2_903-909.pdf863.3 KB

Evidence of the safe period intravitreal tamponade by perfluorodecalin in clinical practice

Year: 2018, volume 14 Issue: №4 Pages: 862-866
Heading: Ophtalmology Article type: Original article
Authors: Arslanov G.M., Aznabaev В.М., Mukhamadeev T.R., Dibaev T.I.
Organization: Saratov State Medical University, The Eye Clinic «Zrenie» (Saint Petersburg)
Summary:

 Purpose: to perform clinical testing of perfluorocarbon liquid on the basis of perfluorodecalin with the possibility of intravitreal postoperative tamponade in patients with vitreoretinal pathology and explain the effectiveness of this practice. Material and Methods. Were evaluated anatomical and clinical results of vitrectomy with PFCL intravitreal tamponade in 105 (113 eyes) patients with severe vitreoretinal pathology. Three observation groups were distinguished: group I (in-traoperative and postoperative intravitreal tamponade by perfluorodecalin, national sample); group II (only intraopera-tive use of perfluorodecalin, foreign sample); group III (only intraoperative use of perfluoro-1.3- dimethylcyclohexane). Results. Retinal attachment in the group of patients with postoperative intravitreal tamponade was 97.1% (visual acuity increased in 71.5% cases). All cases of failure or redetachment, postoperative complications and cataract progression did not have a statistically significant association with postoperative intravitreal tamponade as risk factor (x2=0,316; X2=0,068; x2=0.061; x2=0.403, p>0.05). Conclusion. Clinical testing of perfluorocarbon liquid intravitreal tamponade on the basis of perfluorodecalin in patients with vitreoretinal pathology showed high anatomical and clinical results with a high probability of retinal attachment.

AttachmentSize
2018_4-2_862-866.pdf264.27 KB

Clinical and functional results of surgical treatment of regmatogenous retinal detachment by ultrasonic vitrectomy 25G

Year: 2018, volume 14 Issue: №4 Pages: 841-845
Heading: Ophtalmology Article type: Original article
Authors: Aznabaev В.M., Dibaev T.I., Mukhamadeev T.R., Shatunova A.S.
Organization: Bashkir State Medical University of the Russian Health Care, ZAO Optimedservis
Summary:

Objective: to analyze clinical and functional outcomes of surgical treatment regmatogenic retinal detachment by ultrasound vitrectomy. Material and methods. Clinical and functional results of treatment of 70 patients (70 eyes) with regmatogenous retinal detachment (ROS) who received surgical care in the clinic OPTIMIZED from 2015 to 2018 In the main group (n=33) operations were performed by ultrasound vitrectomy 25G, in the control group (n=37) — by traditional guillotine pneumatic vitrectomy using the tools of the same caliber. During surgery, were analyzed: time of vitrectomy stage (sec), total duration of operation (min), achievement planned anatomical result (%). In the postoperative period (up to 12 months) analyzed: stability of anatomical result (%), maximum corrected visual acuity, intraocular pressure, morphometric criteria retinal conditions (OCT, OCT-angiography), incidence of complicated cataract (%). Results. Average value of vitrectomy stage time in the main group (378.3±125.2 sec) lower than in the control (490.9±175.5 sec), p<0.05. Total duration operations in both groups did not differ, but on average was somewhat shorter in the main group. group (53.6±9.4 and 64.2±23.5 min, respectively). Planned anatomical result in retinal adhesion in all sectors was achieved at the end of the operation in 100% of cases in both groups. No intraoperative complications were recorded in any of the cases. Ultrasonic vitrectomy permits the use of smaller values of the vacuum as on the stage initiation of posterior vitreous detachment (333.3±40.1 mm Hg).St) and at the stage of peripheral vitrectomy (203.2±51.5 mm Hg.art.) compared with traditional vitrectomy, where high vacuum was required: 600 mm Hg.art. at the stage of initiation of ZOST, 305,4±66,4 mm Hg.article on stage of peripheral vitrectomy. The anatomical result remained stable in all terms of the postoperative period in the main group in 100% of cases. In control group relapses of retinal detachment were registered in 8.1% of patients and successfully eliminated conducting an audit of the vitreous cavity. In the late postoperative period the most frequent complication was the development of complicated cataracts (27.1 % in the main group, 40.5% in the control). In both groups, by the 12th month of follow-up, high maximum corrected visual acuity (0.5 and higher in 66.6% of patients and in the main 47.3% of patients in the control group). Conclusion. Comparative study conducted the method of ultrasonic vitrectomy in the surgical treatment of rhegmatogenous detachment the retina has shown that this technique is an effective method that provides and stable anatomical and functional result.

AttachmentSize
2018_4-2_841-845.pdf263.35 KB

Clinical performance of system for ultrasonic cortex aspiration during phacoemulsification

Year: 2018, volume 14 Issue: №4 Pages: 811-815
Heading: Ophtalmology Article type: Original article
Authors: Aznabaev В.М., Dibaev T.I., Mukhamadeev T.R., Idrisova G.M.
Organization: Bashkir State Medical University of the Russian Health Care, ZAO Optimedservis
Summary:

Purpose: to study the performance and safety of the use of system for cortex aspiration with the possibility of additional dosed low power ultrasound during phacoemulsification. Material and Methods. The comparative evaluation of developed system for cortex aspiration with the possibility of additional dosed low power ultrasound (main group, n=36, ophthalmological surgical platform Optimed Profi) and the traditional system for cortex aspiration (control group, n=40, ophthalmological surgical platform Centurion Vision System) were performed. Results. Using the system for cortex aspiration decreases mean time of cortex aspiration. In the main group the mean time of cortex aspiration was 72.6±24.3 s, in the control group 93.9±48.0 s (p<0.05). Intraoperative complications were not observed in the main group. Posterior capsule rupture was detected during the cortex aspiration in 1 patient (2.5%) in the control group. Conclusion. The system for cortex aspiration with the possibility of additional dosed low power ultrasound allows decrease the time of cortex aspiration, to create conditions for a safer removal of cortex, compared with traditional technology.

AttachmentSize
2018_4-2_811-815.pdf636.91 KB