Saratov JOURNAL of Medical and Scientific Research

diabetes II type

The treatment of gastroesophageal reflux disease in menopausal women suffering from diabetes mellitus type II

Year: 2016, volume 12 Issue: №4 Pages: 556-560
Heading: Internal Diseases Article type: Original article
Authors: Semikina Т.М., Kunitsyna M.A., Kashkina E.l.
Organization: Saratov State Medical University
Summary:

Purpose: to develop criteria for the selection of optimal tactics of supporting treatment of nonerosive gastroesophageal reflux disease with proton pump inhibitors in menopausal women suffering from diabetes mellitus type II. Material and Methods. 186 patients aged 45-59 who suffer from gastroesophageal reflux disease have been followed up, 46 of which suffer from diabetes mellitus type II as well. The climacteric syndrome's morbidity has been assessed in accordance with the modified menopause index; the level of glycated hemoglobin has been measured by the Abbott analyzer produced in the USA. Results. It is established that irrespective of the supporting treatment, the gastroesophageal reflux disease remittance was shorter in direct proportion with increase of the HbA1c level and the value of the modified menopause index in menopausal women suffering from diabetes mellitus type II. Conclusion. When the climacteric syndrome was mild or moderate, taking 20 mg Omeprazole once a day and "on demand" has comparable results, therefore this group of women prefer the "on demand" regimen as it lowers the risk of osteoporosis progression and further bone fracture. Taking 20 mg Omeprazole once a day, every other day, and "on demand" allows the disease remittance to prolong for a year and longer in less than 30% of women suffering from severe climacteric syndrome and having HbA1c>9.0%; however, this number may grow up to 70% of women in case they follow medical advice and reduce their carbohydrate input to 11 carbohydrate units and less.

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Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2

Year: 2014, volume 10 Issue: №3 Pages: 461-464
Heading: Endocrinology Article type: Original article
Authors: Rodionova T.l., Orlova M.M.
Organization: Saratov State Medical University
Summary:

Purpose: to estimate efficiency of treatment of analogues of insulin Glargin and insulin Detemir in patients with diabetes type 2. Material and methods. 147 patients with diabetes type 2 which have been initially receiving combined therapy by oral antihyperglycemic agent and NPH-insulin have been under the study. Level of glycated hemoglobin has been defined in 3 and 6 months for the general assessment of control of aglycemia. Results. According to the study the use of insulin analogues (Detemir, Glargin) versus NPH insulin for 6 months allowed to reach individual target values of glycemia in 70% of patients with diabetes type 2 with a low risk of hypoglycemia. Conclusion. The use in clinical practice of modern insulin analogues and simple algorithm for dose titration, allows simulating as closely as possible the physiological insulin secretion, helping to achieve compensation of carbohydrate metabolism in larger numbers of patients in comparison with NPH insulin.

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Dental implants as Treatment Option in Patients With Osteopenic Syndrome and Type II Diabetes

Year: 2009, volume 5 Issue: №2 Pages: 242-244
Heading: Stomatology Article type: Original article
Authors: D.R. Tovmasjan, A.M. Panin, A.M. Mkrtumjan, M.V. Kozlova
Organization: Moscow State Stomatological University
Summary:

One of the important problems in modern dentistry is the study of jaw bone changes associated with type II diabetes. The aim of this study is to evaluate the influence of osteopenic syndrome on osseointegration when using dental implants in patients with type II diabetes. 40 patients with type II diabetes have been evaluated and assigned to two different groups based on the duration of the disease. Including criteria in patients with compensated diabetes were fasting glucose test results

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