Saratov JOURNAL of Medical and Scientific Research

rheumatology

Rituximab treatment efficacy in a patient with systemic lupus erythematosus with severe thrombocytopenia

Year: 2018, volume 14 Issue: №3 Pages: 417-419
Heading: rheumatology Article type: Case report
Authors: Alexandrova O.L., Nikitina N.M., Magdeeva N.A., Shmelkova M.Yu., Grigoryeva S.N.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University
Summary:

The article presents a clinical case of systemic lupus erythematosus with severe thrombocytopenia in a 55 year old patient. The standard therapy of usage of high doses of glucocorticoids, cyclophosphamide and intravenous im-munoglobulin was not effective. Application of Rituximab improved the course of disease, decreased the severity of thrombocytopenia, led to disappearance of leucopenia and anemia.

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