Saratov JOURNAL of Medical and Scientific Research

Privolzhskiy Research Medical University

The role of chronic inflammation in the formation of dentigerous (follicular) cysts of the jaws in children

Year: 2018, volume 14 Issue: №4 Pages: 657-660
Heading: Stomatology Article type: Original article
Authors: Slesareva О.А., Potemina Т.Е.
Organization: Privolzhskiy Research Medical University, Nizhny Novgorod Regional Children's Hospital
Summary:

Purpose: to determine the role of chronic inflammation in deciduous teeth data in the formation of dentigerous (follicular) cysts of the jaws in children; to considerthe pathophysiological mechanism of follicular cysts formation. Material and Methods. Case histories of 134 patients of the department of maxillofacial surgery (dentistry) "Nizhny Novgorod regional children's hospital" from 2003 to 2013 with a diagnosis of "follicular jaw cyst" with different localization. Results. The dental status, specifically centers of chronic inflammation, in the area of follicular cyst formation was assessed. The connection with the ecological situation of the residence area of patients with the prevalence of follicular cysts of the jaws in children was found. Conclusion. The key role of chronic inflammation in the form of complicated forms of caries of temporary teeth for the development of follicular cysts of the jaws. The data of the study (the important role of chronic inflammation of the deciduous teeth in the formation of follicular cysts of the jaws in children) adverse environmental conditions of the place of residence will help to develop principles of prevention and examination for early detection of pathological changes.

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Тhe efficiency of complex treatment of different variants of myasthenia gravis

Year: 2018, volume 14 Issue: №1 Pages: 145-148
Heading: Neurology Article type: Original article
Authors: Lapshina O.V., Antipenko Е.А., Gustov A.V.
Organization: Privolzhskiy Research Medical University
Summary:

The aim: to evaluate the effect of complex restorative treatment on clinical manifestations and the state of oxidative homeostasis in patients with different variants of myasthenia gravis. Material and Methods. The analysis of indicators of biochemiluminescence, muscle strength according to the scales QMGS and MG-ADL, instrumental methods of research (ENMG and respiratory function) before and after treatment in 117 patients with myasthenia gravis is carried out. For comparative analysis of independent samples was used Mann — Whitney U-test, and for paired comparisons was used the Wilcoxon test. Results. The dynamics of oxidative homeostasis, clinical picture, indicators of instrumental methods of research (ENMG, respiratory function) in patients with myasthenia gravis, without thymoma and underwent thymectomy on the background of complex treatment with the use of antioxidant therapy is presented. In all studied groups against the background of complex treatment with application of antioxidant therapy increase in activity of antioxidant protection of organism and decrease in activity of free radical oxidation that correlates with clinical improvement in all groups of patients is noted. Conclusion. The use of antioxidant therapy in complex rehabilitation of patients with myasthenia gravis is pathogenetically justified, especially in patients without thymoma.

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