Saratov JOURNAL of Medical and Scientific Research

cosmetic product "Mellisol"

Evaluation of the wound healing capacity of the gel form of the preparation "Mellisol" on the model of experimental planar wounds

Year: 2017, volume 13 Issue: №3 Pages: 635-640
Heading: Dermatovenerology Article type: Original article
Authors: Myl'nikov A.M., Nechaeva O.V., Zayarskiy D.A., Bespalova N.V., Mudrak D.A., Navolokin N.A.
Organization: Saratov State Medical University, Yuri Gagarin State Technical University of Saratov
Summary:

Objective: to study the wound healing activity of the gel form of the "Mellisol" preparation containing nanoaggregates of flavonoids stabilized with polyazolidine ammonium modified with iodine hydrate ions on a model of experimental planar wounds of rats. Material and Methods. An investigation of the wound healing activity of the gel form of the "Mellisol" preparation was carried out in vivo in 18 white laboratory rats of the Wistar line. Simulation of experimental planar wounds was performed according to the standard procedure described in the preclinical testing manual. Results. In the course of the studies, it was established that a statistically significant (p=0.045) acceleration of healing on the 12th day of the experiment occurred in animals of the experimental group on whose wounds the gel form of the cosmetic means "Mellisol" was applied, and the complete healing of the wound defect occurred on the 21st day after operation. Conclusion. The gel form of the preparation "Mellisol" is characterized by a high level of antimicrobial and regenerative activity reliably reducing the healing time for planar wounds without the development of microbial complications.

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Оценка затрат на лечение пациентов с разными формами псориаза в условиях круглосуточного стационара

Year: 2017, volume 13 Issue: №3 Pages: 612-616
Heading: Dermatovenerology Article type: Original article
Authors: Shnaider D.A., Utz S.R., Zayarskiy D.A., Nechaeva O.V., Guskova O.P.
Organization: Saratov State Medical University, Saratov State Technical University n.a. Yu.A. Gagarin, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

Aim: preliminary studies have made it possible to establish for the polymer a broad spectrum of antimicrobial activity and to attribute it to low-toxic compounds. Material and Methods, the paper presents a comparative evaluation of the treatment of mild and moderate acne with the standard preparation adapalen+clindamycin and cosmetic product Mellisol to change the indices of the dermatological acne index (DAI). Results. The use of the cosmetic product "Mel-lisol" contributed to a significant reduction in the indices of CFU of bacteria. Conclusions. Using of the cosmetic product "Mellisol" is effective in the treatment of acne and showed its high efficacy and safety in the treatment of patients with mild and moderate acne.

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