Saratov JOURNAL of Medical and Scientific Research

vitreoretinal surgery

Light-induced total electrical activity of retina in models of particular disorders in vivo and in vitro

Year: 2018, volume 14 Issue: №4 Pages: 903-909
Heading: Ophtalmology Article type: Original article
Authors: Mukhamadeev T.R., Ahmadeev R.R.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Aim: to conduct an electrophysiological study of functional state of retina under the influence of ophthalmological surgical and typical pathogenic factors on various experimental models. Material and Methods. Experimental registration of electroretinogram (ERG) and total receptor potential (TRP) in vivo and in vitro under influence of various pathogenic factors. Results. It was shown that there is a slight decrease in the amplitude of the ERG in the early postoperative period after vitreoretinal surgery in rabbits followed by almost complete restoration of the electroretinogram to its original values. Registration of electrical activity of isolated retina of amphibians showed a rapid inhibition of a-, b- and d-waves of ERG during anoxia and their recovery during re-oxygenation. TRP inhibition during anoxia is developed more slowly than ERG inhibition, but its recovery does not occur during re-oxygenation. Preparations of isolated retinas with preserved pigment epithelium were much more resistant to oxygen deficiency. The results are discussed from a neurophysiological point of view and are consistent with the paradigm of retinal remodeling in experimental pathology with the leading role of neural mechanisms. Conclusion. The most adequate and effective methodological approach to assess the impact of typical and specific pathogenetic factors on the overall functional state of the retina is to register the total electrical activity of the retina in models in vivo. Studies of more subtle changes at the receptor, neuronal and interneuronal levels under the influence of various extreme factors on the retina are more expedient to carry out on in vitro models with registration of both total and local activity.

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Intraoperative OCT-assisted vitreoretinal surgery

Year: 2018, volume 14 Issue: №4 Pages: 849-855
Heading: Ophtalmology Article type: Original article
Authors: Aznabaev В.М., Dibaev T.l., Husniyarova A.R.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Purpose: comparative analysis of clinical and functional results of surgery of vitreomacular interface and rheg-matogenous retinal detachment with the use of intraoperative optical coherence tomography. Material and Methods. Clinical and morphofunctional data were analyzed in 102 patients with epiretinal fibrosis (ERF), idiopathic macular hole (IMH), and rhegmatogenous retinal detachment (RRD), who were divided into 2 groups. In the main group (n=52), the surgery was performed using intraoperative ОСТ control, in the control group without it. In the main group intraoperative control was performed at 4 stages of the surgery: before vitrectomy, after vitrectomy, during the main stage of the surgery and after completion of endotamponade of the vitreous cavity. During surgery for macular disorders intraoperative complications were assessed, in RRD the intraoperative screening for the detection of undiagnosed pathological changes was performed. In the postoperative period, clinical and functional results were assessed in up to 6 months. Results. The use of intraoperative ОСТ control allowed to reduce the frequency of intraoperative complications, such as capillary retinal bleeding (19.2% in the control group, 11.5% in the main group) and pinching of the inner retinal layers (not observed in the main group, in the control group its incidence was 23.1%) in macular surgery. Intraoperative ОСТ made it possible to better identify concomitant retinal pathology (secondary epiretinal membranes in the main group were found during the surgery in 11.5% of cases, in the control group in 4.2%, while in the postoperative period in 12.5%). In complicated cases of RDD, tomographic control allows to identify microstructural features of the posterior pole of the eye, which are important in achieving stability of the anatomical result, such as retinal defects over staphyloma of the posterior pole in high myopia cases. Conclusion. Intraoperative OCT-assisted vitreoretinal surgery reduces the rate of intraoperative complications during macular surgery and gives valuable diagnostic information in complicated retinal detachment cases.

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Primary surgical rehabilitation of children with posttraumatic endophthalmitis

Year: 2017, volume 13 Issue: №2 Pages: 369-372
Heading: Ophtalmology Article type: Original article
Authors: Yeremenko K.Yu., Alexandrova А.А., Tsypyashchuk A.F.
Organization: Saratov State Medical University
Summary:

Purpose: to analyze the results of microinvasive surgical treatment of children with post-traumatic endophthalmitis. Patients and Methods. Under our observation there were 5 children aged 9-13 years with penetrating wounds of the cornea. All children referred to the clinic with clinical manifestations of endophthalmitis. Visual acuity was reduced from 0,01 up to light perception with the correct projection. Results. Lensvitrectomy allowed to visually detect foreign bodies in vitreous and to remove them through the corneal access. Finished the operation by the intraocular introduction of antibiotics and corticosteroids. Criteria of efficiency of treatment: relief ofthe infectious process, the transparency of optical media, lack of subatrophy ofthe eyeball during the observation period of 3-5 months. Conclusion. Timely primary surgical rehabilitation of children with post-traumatic endophthalmitis appropriate, despite the severity of the injury.

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