Saratov JOURNAL of Medical and Scientific Research

Batischeva Yu.S.

Saratov State Medical University n.a. V.I. Razumovsky, Department of Eye Diseases, Assistant

Modern aspects of diagnostics and monitoring of tape-toretinal degeneration

Year: 2017, volume 13 Issue: №2 Pages: 422-426
Heading: Ophtalmology Article type: Original article
Authors: Nekhorosheva А.А., Popova T.S., Batishcheva Yu.S., Kolbenev I.O.
Organization: Saratov State Medical University
Summary:

Objective: to evaluate the informativity of clinical and instrumental methods of examining patients with tapetoretinal abiotrophy (TRA). Material and Methods. 45 patients with a diagnosis ofTRA, divided into 3 groups: 1) 8 people (under 18 years); 2) 20 people (19-40 years); 3) 17 people (over 41 years). Performed: standard ophthalmological examination, computer perimetry (kinetic, static perimetry in the "Macula threashold 24-2bs" mode, OCULUS Twinfield device), fundus shots (TOPCON device), EPS* (Neuro-MEP device). Results. The average total value of the visual fields of the first group patients amounted to 394±23°, the second group has 173±26° result and the third group has 86±15° result. Mean deviation of the bacillary component of electroretinogram in the first group has reached 53.8±10.4%, 70.2±4.3% in the second group and 84.7±7.3% in the third group. As for the rhythmic component, the indicators were following: 20.3±4.3%, 41.6±5.2%, 62.3±6.4% in the first, second and the third groups respectively. The data of static perimetry showed a decrease in the average photosensitivity in the central parts with respect to the population's age. According to the data of ophthalmoscopy the bony bodies' remoteness of the location from the center of the fundus corresponds to the degree of narrowing of the field of vision. Conclusion. There is a significant relationship between the total value of the peripheral boundaries of the visual field, electroretinogram data and perimetry.

AttachmentSize
2017_02-1_422-426.pdf702.79 KB

Development of ophthalmic training simulator for cataract surgery

Year: 2017, volume 13 Issue: №2 Pages: 417-420
Heading: Ophtalmology Article type: Original article
Authors: Kumova S.V., Lunev I.A., Gasparyan E.A., Virsta A.M., Batishcheva Yu.S., Kamenskikh T.G., Dolinina O.N.
Organization: Saratov State Medical University, Saratov state university, Yuri Gagarin State Technical University of Saratov
Summary:

Purpose: development of interactive simulator for the development of phacoemulsification. Material and Methods. Material and methods: the Software developed by the authors ophthalmic virtual simulator has several modules that can also be complemented by depending on put before the students the task. Testing the virtual simulator "Phacoemulsification" held at the Department of ophthalmology with the participation of 20 interns and 18 residents. Results. The development of residents and interns of ophthalmological profile of the theoretical foundations of cataract surgery using developed by the authors of the publication virtual interactive simulator demonstrated the effectiveness of this technique in comparison with passive viewing of video recording operations and the familiarity with the course of phacoemulsification in the operating room. Conclusion. The application of the developed simulator with the purpose of optimization of educational process of residents and interns of ophthalmic profile is a very effective tool in the world today.

AttachmentSize
2017_02-1_417-420.pdf501.59 KB

Experience of antiangiogenic and corticosteroid therapy of a diabetic macular edema

Year: 2017, volume 13 Issue: №2 Pages: 383-388
Heading: Ophtalmology Article type: Original article
Authors: Kamenskikh T.G., Batishcheva Yu.S., Kolbenev I.O., Tsipyashchyk A.F., Andreychenko O.A., Gileva E.M., Vasil'yeva T.V., Zakharova N.B.
Organization: Saratov State Medical University
Summary:

Diabetic macular edema (DME) is a leading cause of blindness in patients with diabetes. The purpose of the research is to evaluate the effectiveness of treatment of patients with DMOs resistant to the administration of ranibi-zumab, using the intrauritreal implant "Ozurdex". Material and Methods. 66 patients (98 eyes) are examined. All of the patients were divided, into three groups, depending on a stage of a diabetic retinopathy. The patients underwent a complex of examinations: along with traditional methods, optical coherence tomography, fluorescence angiography of the fundus, multifocal electroretinography, determination of the content of VEGF-Aand cytokines in serum were used. Results. According to ОСТ of a retina and a visometry there are differences in efficiency of treatment depending on a condition balance of cytokine. Conclusion. The use of the intrauretic implant "Ozurdex" was more effective in patients with DMO in the stage of p re-pro I iterative diabetic retinopathy and in patients resistant to anti-VEGF therapy.

AttachmentSize
2017_02-1_383-388.pdf2.1 MB

Computer analysis of epiretinal membrane parameters

Year: 2017, volume 13 Issue: №2 Pages: 350-358
Heading: Ophtalmology Article type: Original article
Authors: Daurov S.K., Dolinina O.N., Kamenskikh T.G., Batischeva Yu.S., Kolbenev I.O., Andreychenko O.A., Potemkin S.A., Proskudin R.A.
Organization: Yuri Gagarin State Technical University of Saratov, Saratov State Medical University
Summary:

Objective: to develop algorithms of processing of video images of optical slices of the eye retina to quantify the degree of folding of the epiretinal membranes and of the central fossa. Material and methods. The object of the study was the video image of the retina obtained by optical coherence tomography. To develop methods of determining the degree of folding epiretinal membrane was formed mathematical model of the profile consisting of a base profile (low frequency component) and folding (high frequency part). Results. There had been developed two alternative methods of estimation of folding epiretinal membrane: retinal-averaging method and the method using the wavelet transform. The algorithm of geometrical parameters of the central fossa: the height, width and line shape. These algorithms are implemented in a software system. Conclusion. The practical application of the developed system showed its adequacy, as well as an introduction into medical practice the use of quantitative estimates of some parameters of the retina condition.

AttachmentSize
2017_02-1_350-358.pdf3.21 MB